GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
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The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
Citations
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Micronutrient fortification of food and its impact on woman and child health: a systematic review
TL;DR: The results for fortification in women showed that calcium and vitamin D fortification had significant impacts in the post-menopausal age group, and iron fortification led to a significant increase in serum ferritin and hemoglobin levels in women of reproductive age and pregnant women.
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Dual equipoise shared decision making: definitions for decision and behaviour support interventions
TL;DR: Decision and behaviour support interventions have divergent aims, different relationships to equipoise, and form two classes of interventions that have relevant and important consequences for those who are considering behaviour change.
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Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations
Steven H. Woolf,Holger J. Schünemann,Martin P Eccles,Jeremy M. Grimshaw,Jeremy M. Grimshaw,Paul G. Shekelle,Paul G. Shekelle +6 more
TL;DR: Issues of identifying and synthesizing evidence: deciding what type of evidence and outcomes to include in guidelines; integrating values into a guideline; incorporating economic considerations; synthesis, grading, and presentation of evidence; and moving from evidence to recommendations are discussed.
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Supporting the delivery of cost-effective interventions in primary health-care systems in low-income and middle-income countries: an overview of systematic reviews.
Simon Lewin,Simon Lewin,John N. Lavis,Andrew D Oxman,Gabriel Bastías,Mickey Chopra,Agustín Ciapponi,Signe Flottorp,Sebastián García Martí,Tomas Pantoja,Gabriel Rada,Nathan M Souza,Shaun Treweek,Charles Shey Wiysonge,Andy Haines +14 more
TL;DR: This overview summarises the evidence from systematic reviews of health systems arrangements and implementation strategies, with a particular focus on evidence relevant to primary health care in low-income and middle-income countries.
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Opioid agonist treatment for pharmaceutical opioid dependent people.
Suzanne Nielsen,Briony Larance,Louisa Degenhardt,Linda Gowing,Chyanne Kehler,Nicholas Lintzeris +5 more
TL;DR: Low to moderate quality evidence supporting the use of maintenance agonist pharmacotherapy for pharmaceutical opioid dependence is found, and maintenance treatment with buprenorphine appeared more effective than detoxification or psychological treatments.
References
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David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
TL;DR: The objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach.