scispace - formally typeset
Open AccessJournal ArticleDOI

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

Reads0
Chats0
TLDR
The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Abstract
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwide

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

ACG clinical guideline: diagnosis and management of achalasia

TL;DR: This ACG guideline presents an evidence-based approach in patients with achalasia based on a comprehensive review of the pertinent evidence and examination of relevant published data.
Journal ArticleDOI

Visualizing Uncertainty About the Future

TL;DR: This review of current practice for communicating uncertainties visually, using examples drawn from sport, weather, climate, health, economics, and politics, shows how the effectiveness of some graphics clearly depends on the relative numeracy of an audience.
Journal ArticleDOI

Adiposity and cancer at major anatomical sites: umbrella review of the literature.

TL;DR: Obesity is becoming one of the biggest problems in public health; evidence on the strength of the associated risks may allow finer selection of those at higher risk of cancer, who could be targeted for personalised prevention strategies.
Journal ArticleDOI

EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.

TL;DR: The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction, however, it refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease.
Journal ArticleDOI

Guidelines for the management of tracheal intubation in critically ill adults

TL;DR: These guidelines describe a comprehensive strategy to optimize oxygenation,Airway management, and tracheal intubation in critically ill patients, in all hospital locations, and stress the role of the airway team, a shared mental model, planning, and communication throughout airway management.
References
More filters
Journal ArticleDOI

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial

TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI

Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women

TL;DR: Treatment with oral conjugated equine estrogen plus medroxyprogesterone acetate did not reduce the overall rate of CHD events in postmenopausal women with established coronary disease and the treatment did increase the rate of thromboembolic events and gallbladder disease.
Journal ArticleDOI

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.

TL;DR: There was an excess of deathsDue to arrhythmia and deaths due to shock after acute recurrent myocardial infarction in patients treated with encainide or flecainide.
Journal ArticleDOI

A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.

TL;DR: Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Related Papers (5)