GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
Reads0
Chats0
TLDR
The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.Abstract:
Guidelines are inconsistent in how they rate the quality of evidence and the strength of recommendations. This article explores the advantages of the GRADE system, which is increasingly being adopted by organisations worldwideread more
Citations
More filters
Journal ArticleDOI
A systematic review of the global prevalence of low back pain
Damian G Hoy,Chris Bain,Gail M. Williams,Lyn March,Peter Brooks,Fiona M. Blyth,Anthony D. Woolf,Theo Vos,Rachelle Buchbinder +8 more
TL;DR: As the population ages, the global number of individuals with low back pain is likely to increase substantially over the coming decades, with the highest prevalence among female individuals and those aged 40-80 years.
Journal ArticleDOI
2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis
Jasvinder A. Singh,Kenneth G. Saag,S. Louis Bridges,Elie A. Akl,Raveendhara R. Bannuru,Matthew C. Sullivan,Elizaveta E. Vaysbrot,Christine McNaughton,Mikala C. Osani,Robert H. Shmerling,Jeffrey R. Curtis,Daniel E. Furst,Deborah Parks,Arthur Kavanaugh,James R. O'Dell,Charles H. King,Amye Leong,Eric L. Matteson,John T. Schousboe,Barbara E. Drevlow,Seth Ginsberg,James Grober,E. William St. Clair,Elizabeth A. Tindall,Amy S. Miller,Timothy E. McAlindon +25 more
TL;DR: To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid arthritis (RA), a large number of patients with RA are referred to a single clinic for treatment with these medications.
Journal ArticleDOI
GRADE guidelines: A new series of articles in the Journal of Clinical Epidemiology △
TL;DR: This article introduces a 20-part series providing guidance for the use of GRADE methodology that will appear in the Journal of Clinical Epidemiology.
Journal ArticleDOI
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU
John W. Devlin,John W. Devlin,Yoanna Skrobik,Céline Gélinas,Dale M. Needham,Arjen J. C. Slooter,Pratik P. Pandharipande,Paula L. Watson,Gerald L. Weinhouse,Mark E. Nunnally,Bram Rochwerg,Michele C. Balas,Mark van den Boogaard,Karen J. Bosma,Karen J. Bosma,Nathaniel E. Brummel,Gerald Chanques,Linda Denehy,Xavier Drouot,Gilles L. Fraser,Jocelyn E. Harris,Aaron M. Joffe,Michelle E. Kho,John P. Kress,Julie A. Lanphere,Sharon McKinley,Karin J. Neufeld,Margaret A. Pisani,Jean François Payen,Brenda T. Pun,Kathleen Puntillo,Richard R. Riker,Bryce R.H. Robinson,Yahya Shehabi,Paul M. Szumita,Chris Winkelman,John Centofanti,Carrie Price,Sina Nikayin,Cheryl Misak,Pamela Flood,Ken Kiedrowski,Waleed Alhazzani +42 more
TL;DR: Substantial agreement was found among a large, interdisciplinary cohort of international experts regarding evidence supporting recommendations, and the remaining literature gaps in the assessment, prevention, and treatment of Pain, Agitation/sedation, Delirium, Immobility (mobilization/rehabilitation), and Sleep (disruption) in critically ill adults.
References
More filters
Journal ArticleDOI
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
Jacques E. Rossouw,Garnet L. Anderson,Ross L. Prentice,Andrea Z. LaCroix,Charles Kooperberg,Marcia L. Stefanick,Rebecca D. Jackson,Shirley A.A. Beresford,Barbara V. Howard,Karen C. Johnson,Jane Morley Kotchen,Judith K. Ockene +11 more
TL;DR: Overall health risks exceeded benefits from use of combined estrogen plus progestin for an average 5.2-year follow-up among healthy postmenopausal US women, and the results indicate that this regimen should not be initiated or continued for primary prevention of CHD.
Journal ArticleDOI
Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women
Stephen B. Hulley,Deborah Grady,Trudy L. Bush,Curt D Furberg,David M. Herrington,Betty Riggs,Eric Vittinghoff +6 more
TL;DR: Treatment with oral conjugated equine estrogen plus medroxyprogesterone acetate did not reduce the overall rate of CHD events in postmenopausal women with established coronary disease and the treatment did increase the rate of thromboembolic events and gallbladder disease.
Journal ArticleDOI
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.
Echt Ds,Philip R. Liebson,Mitchell Lb,Robert W. Peters,Obias-Manno D,Barker Ah,Arensberg D,Baker A,Lawrence S. Friedman,Greene Hl +9 more
TL;DR: There was an excess of deathsDue to arrhythmia and deaths due to shock after acute recurrent myocardial infarction in patients treated with encainide or flecainide.
Journal ArticleDOI
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.
TL;DR: Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Journal ArticleDOI
Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches The GRADE Working Group.
David Atkins,Martin P Eccles,Signe Flottorp,Gordon H. Guyatt,David Henry,Suzanne Hill,Alessandro Liberati,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Holger J. Schünemann,Tessa Tan-Torres Edejer,Gunn Elisabeth Vist,John W Williams +14 more
TL;DR: The objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach.