MicroRNAs in Cardiovascular Disease
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TLDR
An introduction to miRNA biology and research methodology is provided, and advances in cardiovascular research to date are highlighted, including the potential of miRNAs as therapeutic targets in cardiac and vascular disease, and their use as novel biomarkers.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2016-12-13 and is currently open access. It has received 362 citations till now. The article focuses on the topics: Gene silencing.read more
Citations
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MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
TL;DR: Recent advances in the understanding of miRNAs in cancer and in other diseases are described and the challenge of identifying the most efficacious therapeutic candidates is discussed and a perspective on achieving safe and targeted delivery of miRNA therapeutics is provided.
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Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity.
TL;DR: A contemporary view is provided of the instigators of diabetic cardiomyopathy, as well as mechanistically based strategies for the prevention and treatment of diabetic CARDIomyopathy.
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miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
Shanshan Zhou,Jingpeng Jin,Jiqun Wang,Jiqun Wang,Zhiguo Zhang,Zhiguo Zhang,Jonathan H. Freedman,Yang Zheng,Lu Cai +8 more
TL;DR: The effects of several CVD; including heart failure, acute myocardial infarction, arrhythmias and pulmonary hypertension; on levels of circulating miRNAs are provided, as well as challenges and recommendations in their use in the diagnosis of CVD.
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Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases
Ana L. Cardoso,Adelaide Fernandes,Juan Antonio Aguilar-Pimentel,Martin Hrabé de Angelis,Joana R. Guedes,Maria Alexandra Brito,Saida Ortolano,Giovambattista Pani,Sophia Athanasopoulou,Efstathios S. Gonos,Markus Schosserer,Johannes Grillari,Pärt Peterson,Bilge Guvenc Tuna,Soner Dogan,Angelika Meyer,Ronald van Os,Anne-Ulrike Trendelenburg +17 more
TL;DR: Biomarker panels for frailty would be of high value and better than single markers.
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Interplay between miRNAs and human diseases
Prosenjit Paul,Anindya Chakraborty,Debasree Sarkar,Malobika Langthasa,Musfhia Rahman,Minakshi Bari,Rk. Sanamacha Singha,Arup Kumar Malakar,Supriyo Chakraborty +8 more
TL;DR: This review summarized the current understanding of interactions between miRNAs and different diseases and their role in disease diagnosis and therapy.
References
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Sequence the Human Genome
TL;DR: This book aims to provide a history of Chinese modern art from 17th Century to the present day through the lens of 20th Century critics, practitioners, journalists, and mediaeval and modern-day critics.
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