Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance
A-P Magiorakos,Arjun Srinivasan,R B Carey,Yehuda Carmeli,Matthew E. Falagas,Matthew E. Falagas,Christian G. Giske,Stéphan Juergen Harbarth,Janet F. Hindler,Gunnar Kahlmeter,Barbro Olsson-Liljequist,David L. Paterson,Louis B. Rice,John Stelling,Marc Struelens,Alkiviadis Vatopoulos,J T Weber,Dominique L Monnet +17 more
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A group of international experts came together through a joint initiative by the European Centre for Disease Prevention and Control and the Centers for Disease Control and Prevention, to create a standardized international terminology with which to describe acquired resistance profiles in Staphylococcus aureus, Enterococcus spp.About:
This article is published in Clinical Microbiology and Infection.The article was published on 2012-03-01 and is currently open access. It has received 8695 citations till now. The article focuses on the topics: Extensively drug resistant bacteria & Multiple drug resistance.read more
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Virulence Factors and Antibiotic Susceptibility of Staphylococcus aureus Isolates in Ready-to-Eat Foods: Detection of S. aureus Contamination and a High Prevalence of Virulence Genes
TL;DR: The high rate of S. aureus contamination in the sampled sushi and sashimi indicates the need for food safety guidelines and identifies a high incidence of virulence genes.
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The highly synergistic, broad spectrum, antibacterial activity of organic acids and transition metals
TL;DR: It is demonstrated that organic acids shuttle transition metals through the permeability barrier of the bacterial membrane, leading to increased influx of transition metals into bacterial cells, and this synergy can be effectively used to inhibit the growth of a broad range of plant and human bacterial pathogens.
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Antimicrobial resistance and resistance mechanisms of Enterobacteriaceae in ICU and non-ICU wards in Europe and North America: SMART 2011–2013
TL;DR: Antimicrobial resistance was higher in Europe than North America, especially in ICUs, and further surveillance at the country, hospital and even patient ward level, would be useful for the development of effective strategies to reduce antimicrobial resistance in ICU.
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A Hydrogel-Based Localized Release of Colistin for Antimicrobial Treatment of Burn Wound Infection
Chongyu Zhu,Jinxin Zhao,Kristian Kempe,Kristian Kempe,Paul Wilson,Paul Wilson,Jiping Wang,Tony Velkov,Jian Li,Thomas P. Davis,Michael R. Whittaker,David M. Haddleton,David M. Haddleton +12 more
TL;DR: It is believed the colistin-loaded hydrogel to be a potential localized wound-healing formulation to treat burn wounds against microbial infection and the biodegradability of the product is believed.
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Clinically relevant antimicrobial resistance at the wildlife-livestock-human interface in Nairobi: an epidemiological study.
James M. Hassell,James M. Hassell,Melissa J. Ward,Melissa J. Ward,Dishon Muloi,Dishon Muloi,Judy M. Bettridge,Judy M. Bettridge,Timothy P. Robinson,S. Kariuki,Allan Ogendo,John Kiiru,Titus Imboma,Erastus K. Kang'ethe,Elin M. Öghren,Nicola J. Williams,Michael Begon,Mark E. J. Woolhouse,Eric M. Fèvre,Eric M. Fèvre +19 more
TL;DR: Urban wildlife carry a high burden of clinically relevant antimicrobial-resistant E coli in Nairobi, exhibiting resistance to drugs considered crucial for human medicine by WHO, and results provide novel insight into the broader epidemiology of antimicrobial resistance in complex urban environments.
References
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Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
Helen W. Boucher,George H. Talbot,John S. Bradley,John S. Bradley,John E. Edwards,John E. Edwards,David N. Gilbert,Louis B. Rice,Louis B. Rice,Michael Scheld,Brad Spellberg,Brad Spellberg,John G. Bartlett +12 more
TL;DR: An update on potentially effective antibacterial drugs in the late-stage development pipeline is provided, in the hope of encouraging collaboration between industry, academia, the National Institutes of Health, the Food and Drug Administration, and the Centers for Disease Control and Prevention work productively together.
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Antimicrobial-Resistant Pathogens Associated with Healthcare- Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010
Dawn M. Sievert,Philip Ricks,Jonathan R. Edwards,Amy Schneider,Jean B. Patel,Arjun Srinivasan,Alex Kallen,Brandi Limbago,Scott K. Fridkin +8 more
TL;DR: The frequency of selected antimicrobial resistance patterns among pathogens causing device-associated and procedure-associated healthcare-associated infections reported by hospitals in the National Healthcare Safety Network (NHSN) is described.
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Comparison of mortality associated with methicillin-resistant and methicillin-susceptible staphylococcus aureus bacteremia: A meta-analysis
Sara E. Cosgrove,George Sakoulas,Eli N. Perencevich,Mitchell J. Schwaber,Adolf W. Karchmer,Yehuda Carmeli,Yehuda Carmeli +6 more
TL;DR: A meta-analysis was performed to summarize the impact of methicillin-resistance on mortality in Staphylococcus aureus bacteremia and explored the reasons for heterogeneity by means of subgroup analyses.
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Extended-spectrum β-lactamase-producing Enterobacteriaceae: an emerging public-health concern
TL;DR: More rapid diagnostic testing of ESBL-producing bacteria and the possible modification of guidelines for community-onset bacteraemia associated with UTIs are required.
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The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting
TL;DR: The data suggest that clinical efforts should be aimed at reducing the administration of inadequate antimicrobial treatment to hospitalized patients with bloodstream infections, especially individuals infected with antibiotic-resistant bacteria and Candida species.