Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TLDR
There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.About:
This article is published in Journal of Hepatology.The article was published on 2008-02-01. It has received 1172 citations till now. The article focuses on the topics: HBeAg & Hepatitis B.read more
Citations
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Journal ArticleDOI
Mass spectrometry-based plasma peptide profiling of acute exacerbation in HBeAg-positive chronic hepatitis B.
Eric C. Han,Ying Shiung Lee,Yu Ching Liu,Hsin Yi Liao,Wen Sin Liao,Hsueh Chou Lai,Cheng Yuan Peng,Long Bin Jeng +7 more
TL;DR: It is demonstrated that HIC C18 fractionation coupled with MALDI-TOF mass spectrometry can be used for differentiating AE with and without decompensation in patients with HBeAg-positive CHB.
Journal ArticleDOI
Mathematical investigation of HBeAg seroclearance.
Sarah Kadelka,Stanca M. Ciupe +1 more
TL;DR: Quantification of the time between antibody expansion and hepatitis B e antigen seroclearance in the presence and absence of treatment shows that potent short-term treatment speeds up the time around antibody expansion.
Dissertation
Chronic Liver Diseases: With a Focus on Hepatitis B, Type 2 Diabetes and Statins
TL;DR: This book aims to provide a history of co-authorship in the field of literature and investigates its roots in the fields of criticism, criticism and criticism.
Journal ArticleDOI
Tenofovir monotherapy after achieving complete viral suppression on entecavir plus tenofovir combination therapy.
Lily H. Kim,Kevin T. Chaung,Nghiem B. Ha,Kevin C. Kin,Vinh D. Vu,Huy N. Trinh,Huy A. Nguyen,Mindie H. Nguyen +7 more
TL;DR: TDF monotherapy may be considered for some ETV partial responders who have achieved CVS with combination therapy, given the financial advantage and convenience of monotherapy.
Journal ArticleDOI
The correlations between hepatitis B virus infection and hepatocellular carcinoma with portal vein tumor thrombus or extrahepatic metastasis.
TL;DR: HBV infection and replication status are associated with the formation of PVTT or extrahepatic metastasis in patients with HCC.
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
Journal ArticleDOI
Chronic hepatitis B
Anna S. Lok,Brian J. McMahon +1 more
TL;DR: These guidelines have been written to assist physicians and other health care providers in the recognition, diagnosis, and management of patients chronically infected with the hepatitis B virus (HBV).
Journal ArticleDOI
The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
TL;DR: HBV and HCV infections account for the majority of cirrhosis and primary liver cancer throughout most of the world, highlighting the need for programs to prevent new infections and provide medical management and treatment for those already infected.
Journal ArticleDOI
Hepatocellular carcinoma in cirrhosis: incidence and risk factors.
TL;DR: Further studies are needed to investigate other viral factors (eg, HBV genotype/mutant, occult HBV, HIV coinfection) and preventable or treatable comorbidities ( eg, obesity, diabetes) in the HCC risk in cirrhosis.