Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TLDR
There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.About:
This article is published in Journal of Hepatology.The article was published on 2008-02-01. It has received 1172 citations till now. The article focuses on the topics: HBeAg & Hepatitis B.read more
Citations
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Journal ArticleDOI
Investigation of the risk factors associated with the failure of hepatitis B vaccination of neonates in Yunnan province, China.
TL;DR: It was very important to improve the HBV vaccine inoculation rates and delivering babies in hospital and timely inoculation withHBV vaccine were efficient ways to prevent HBV vertical transmission.
Journal ArticleDOI
Systematic review of hepatocellular carcinoma mortality rates among hepatitis B virus-infected renal transplant recipients, with supplemental analyses of liver failure and all-cause mortality.
TL;DR: Mortality due to HCC was increased in low and intermediate seroprevalence areas, but the evidence was inconclusive for high serop revalent areas.
Journal ArticleDOI
Validation of risk prediction scores for hepatocellular carcinoma in patients with chronic hepatitis B treated with entecavir or tenofovir.
Jin Won Chang,Jae Seung Lee,Hye Won Lee,Beom Kyung Kim,Jun Yong Park,Do Young Kim,Sang Hoon Ahn,Yeon Seok Seo,Han Ah Lee,Mi Na Kim,Yu Rim Lee,Seong Gyu Hwang,Kyu Sung Rim,Soon Ho Um,Won Young Tak,Young Oh Kweon,Soo-Young Park,Seung Up Kim +17 more
TL;DR: In conclusion, four HCC prediction scores were assessed in Korean CHB patients treated with ETV or TDF and the AASL score showed the highest predictive accuracy.
Journal ArticleDOI
The impact of the CB2-63 polymorphism on the histological presentation of chronic hepatitis B
Nicola Coppola,Rosa Zampino,Giulia Bellini,Maria Stanzione,Nicolina Capoluongo,Aldo Marrone,Margherita Macera,Giuseppe Pasquale,Adriana Boemio,Sabatino Maione,Le Adinolfi,E. Miraglia del Giudice,Evangelista Sagnelli,F. Rossi +13 more
TL;DR: The observation that the CB2-63 RR variant is an independent predictor of extensive necroinflammation opens up new prospects in the study of CHB.
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Assessment of liver fibrosis by ultrasound elastography and contrast-enhanced ultrasound: a randomized prospective animal study.
TL;DR: Both CEUS and pSWE had the potential to be complementary imaging tools in the evaluation of liver fibrosis and may be better than CEUS, and PV-Imax and LSV displayed better diagnostic performance than PV-RT, PV-TTP, PV -MTT.
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
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Chronic hepatitis B
Anna S. Lok,Brian J. McMahon +1 more
TL;DR: These guidelines have been written to assist physicians and other health care providers in the recognition, diagnosis, and management of patients chronically infected with the hepatitis B virus (HBV).
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The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
TL;DR: HBV and HCV infections account for the majority of cirrhosis and primary liver cancer throughout most of the world, highlighting the need for programs to prevent new infections and provide medical management and treatment for those already infected.
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Hepatocellular carcinoma in cirrhosis: incidence and risk factors.
TL;DR: Further studies are needed to investigate other viral factors (eg, HBV genotype/mutant, occult HBV, HIV coinfection) and preventable or treatable comorbidities ( eg, obesity, diabetes) in the HCC risk in cirrhosis.