Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TLDR
There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.About:
This article is published in Journal of Hepatology.The article was published on 2008-02-01. It has received 1172 citations till now. The article focuses on the topics: HBeAg & Hepatitis B.read more
Citations
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Journal ArticleDOI
Clinical performance of a new hepatitis B surface antigen quantitative assay with automatic dilution.
Ta-Wei Liu,Ming-Lun Yeh,Chung-Feng Huang,I.-Ling Lin,Jee-Fu Huang,Chia-Yen Dai,Yao-Li Chen,Wan-Long Chuang,Ming-Lung Yu +8 more
TL;DR: The Abbott automatic dilution Architect assay provided a good clinical performance with regard to the HBsAg levels and showed good reproducibility and linearity, particularly in the HBeAg‐negative and low DNA groups.
Journal ArticleDOI
Laparoscopic findings of reddish markings predict hepatocellular carcinoma in patients with hepatitis B virus-related liver disease
Bon Shoji,Fusao Ikeda,Shin Fujioka,Haruhiko Kobashi,Tetsuya Yasunaka,Yasuhiro Miyake,Hidenori Shiraha,Akinobu Takaki,Kazuhiro Nouso,Yoshiaki Iwasaki,Kazuhide Yamamoto +10 more
TL;DR: In this article, a systematic cohort analysis of 303 consecutive patients with hepatitis B e-antigen, receiving laparoscopic examination for assessment of liver disease, was performed to predict hepatocellular carcinoma (HCC) development.
Journal ArticleDOI
Application strategies of serum HBV DNA detection in HBV infection patients: A retrospective study of 5611 specimens
Can Liu,Wennan Wu,Shongyan Shang,Er Huang,Zhen Xun,Jinpiao Lin,Tianbin Chen,Bin Yang,Jing Chen,Qishui Ou +9 more
TL;DR: In this paper, the dynamic changes of hepatitis B virus (HBV) DNA and surface antigen (HBsAg), hepatitis B e-antigen (HBeAg), alanine transaminase (ALT), aspartate transaminases (AST), and liver enzymes (HEAs) were reviewed in 5611 cases with suspected hepatitis B infection.
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
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Chronic hepatitis B
Anna S. Lok,Brian J. McMahon +1 more
TL;DR: These guidelines have been written to assist physicians and other health care providers in the recognition, diagnosis, and management of patients chronically infected with the hepatitis B virus (HBV).
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The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
TL;DR: HBV and HCV infections account for the majority of cirrhosis and primary liver cancer throughout most of the world, highlighting the need for programs to prevent new infections and provide medical management and treatment for those already infected.
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Hepatocellular carcinoma in cirrhosis: incidence and risk factors.
TL;DR: Further studies are needed to investigate other viral factors (eg, HBV genotype/mutant, occult HBV, HIV coinfection) and preventable or treatable comorbidities ( eg, obesity, diabetes) in the HCC risk in cirrhosis.