Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TLDR
There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.About:
This article is published in Journal of Hepatology.The article was published on 2008-02-01. It has received 1172 citations till now. The article focuses on the topics: HBeAg & Hepatitis B.read more
Citations
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Infections at the nexus of metabolic-associated fatty liver disease.
Joost Boeckmans,Matthias Rombaut,Thomas Demuyser,Baptist Declerck,Denis Pierard,Vera Rogiers,Joery De Kock,Luc Waumans,K. Magerman,Reinoud Cartuyvels,Jean-Luc Rummens,Robim Marcelino Rodrigues,Tamara Vanhaecke +12 more
TL;DR: In this article, the molecular and cellular mechanisms by which the most relevant viral, bacterial and parasitic infections influence the progression of fatty liver disease and steatohepatitis are discussed.
Journal ArticleDOI
Demographics and outcomes of hepatitis B and D: A 10-year retrospective analysis in a Swiss tertiary referral center.
Joana Vieira Barbosa,Joana Vieira Barbosa,Roland Sahli,Vincent Aubert,Aziz Chaouch,Darius Moradpour,Montserrat Fraga +6 more
TL;DR: In this article, the demographic and clinical characteristics, treatment rates and outcomes of adult patients with chronic hepatitis B infection with or without HDV coinfection examined at Lausanne University Hospital, Switzerland over a 10-year period were retrospectively analyzed using logistic regression.
Journal Article
Epidemiological and laboratory features of chronic hepatitis B cases in the interval 2010-2013.
Alexandru Luca,Carmen Dorobăţ,Ramona Gabriela Ursu,Mihaela Catalina Luca,A Vâţă,Luminiţa Smaranda Iancu +5 more
TL;DR: The correlation between the level of viral load and fibrosis shows that there are significant differences between viremia and the status of HBeAg-positive or negative patients, and the increasing fibrosis prevalence was correlated with low viral load.
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Does hepatitis B virus therapy reduce the risk of hepatocellular carcinoma
TL;DR: This review highlights the results of previous studies conducted on HCC prevention with long-term NUC therapy and shows that they can be safely and effectively used for this purpose.
Journal ArticleDOI
Hepatitis C virus and hepatitis B virus in patients with schizophrenia.
TL;DR: In this article, the authors evaluated the severe hepatic outcome (SHO) in patients with schizophrenia and viral hepatitis who received antipsychotics and found that the SHO risk increased by 3.58 (95% confidence interval [CI]: 1.859-6.754; P < 0.0001).
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
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Chronic hepatitis B
Anna S. Lok,Brian J. McMahon +1 more
TL;DR: These guidelines have been written to assist physicians and other health care providers in the recognition, diagnosis, and management of patients chronically infected with the hepatitis B virus (HBV).
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The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
TL;DR: HBV and HCV infections account for the majority of cirrhosis and primary liver cancer throughout most of the world, highlighting the need for programs to prevent new infections and provide medical management and treatment for those already infected.
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Hepatocellular carcinoma in cirrhosis: incidence and risk factors.
TL;DR: Further studies are needed to investigate other viral factors (eg, HBV genotype/mutant, occult HBV, HIV coinfection) and preventable or treatable comorbidities ( eg, obesity, diabetes) in the HCC risk in cirrhosis.