Journal ArticleDOI
Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors
TLDR
There is a growing understanding of viral, host and environmental factors influencing disease progression, which ultimately could improve the management of chronic hepatitis B.About:
This article is published in Journal of Hepatology.The article was published on 2008-02-01. It has received 1172 citations till now. The article focuses on the topics: HBeAg & Hepatitis B.read more
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Journal ArticleDOI
Virological profile of hepatitis B infection in Black African HBsAg chronic carriers
Koffi Alain Attia,Stanislas Doffou,Ya Henriette Kissi,Demba Bangoura,Seka Mondesir Pianiza,Kouame Alassan Mahassadi,Fulgence Yao Bathaix,Mohamed Sayegh,Thérèse N'Dri-Yoman +8 more
TL;DR: The virological profile of patients followed-up for chronic Hepatitis B virus (HBV) was dominated by HBeAg-negative chronic HBV and HBV inactive chronic carriage, and the risk of having cirrhosis was multiplied by 8.6 in case of active chronic hepatitis compared with HBV active chronic carriage.
Journal ArticleDOI
Diagnostic Approach to Hepatitis B Virus (HBV) Infection
TL;DR: The various tests utilized in the diagnosis of HBV infection are reviewed and their roles in the identification of the different phases of infection and in the determination of the need for further management are reviewed.
Journal ArticleDOI
Analysis of clinical and virologic features in Hepatitis B e Antigen (HbeAg)-negative and HbeAg-positive Egyptian chronic hepatitis B patients.
TL;DR: HBeAg-negative patients compared with H beAg-positive patients had older age, lower ALT and serum HBVDNA levels, but more incidence of HCC.
Journal ArticleDOI
Liver fibrosis scores and risk of liver-related mortality in young adults with chronic hepatitis B: A cohort study
TL;DR: In this article, the authors examined the association of liver fibrosis scores with liver-related mortality in young (<40 years) and older adults with hepatitis B virus (HBV) infection.
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
Chien-Jen Chen,Hwai I. Yang,Jun Su,C.-L. Jen,San Lin You,Sheng-Nan Lu,Guan-Tarn Huang,Uchenna H. Iloeje +7 more
TL;DR: Elevated serum HBV DNA level (> or =10,000 copies/mL) is a strong risk predictor of hepatocellular carcinoma independent of HBeAg, serum alanine aminotransferase level, and liver cirrhosis.
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Chronic hepatitis B
Anna S. Lok,Brian J. McMahon +1 more
TL;DR: These guidelines have been written to assist physicians and other health care providers in the recognition, diagnosis, and management of patients chronically infected with the hepatitis B virus (HBV).
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The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
TL;DR: HBV and HCV infections account for the majority of cirrhosis and primary liver cancer throughout most of the world, highlighting the need for programs to prevent new infections and provide medical management and treatment for those already infected.
Journal ArticleDOI
Hepatocellular carcinoma in cirrhosis: incidence and risk factors.
TL;DR: Further studies are needed to investigate other viral factors (eg, HBV genotype/mutant, occult HBV, HIV coinfection) and preventable or treatable comorbidities ( eg, obesity, diabetes) in the HCC risk in cirrhosis.