Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
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TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
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Journal ArticleDOI
A Systematic Comparative Study on the Diagnostic Value of Transabdominal Ultrasound in Patients with Pancreatic Cystic Lesions
Viktoria Hentschel,Jennice Beckmann,Wolfgang Kratzer,Frank Arnold,Thomas Seufferlein,B. Walter,Alexander Kleger,Martin Müller +7 more
TL;DR: Analysis of cyst detection rates of latest-generation ultrasound machines compared to magnetic resonance imaging, computed tomography, and endosonographic ultrasound and to determine inter-rater reliability showed that large cysts facilitate their visualization by transabdominal ultrasound while detection rates are independent of the anatomical part of the pancreas in which they were sited.
Journal ArticleDOI
Clinical Outcomes of Intraductal Papillary Mucinous Neoplasms With Dilatation of the Main Pancreatic Duct.
Tsuyoshi Hamada,Hiroki Oyama,Yousuke Nakai,Shuichi Tange,Junichi Arita,Ryunosuke Hakuta,Hideaki Ijichi,Kazunaga Ishigaki,Sachiko Kanai,Yoshikuni Kawaguchi,Hirofumi Kogure,Suguru Mizuno,Kei Saito,Tomotaka Saito,Tatsuya Sato,Yasunori Suzuki,Naminatsu Takahara,Mariko Tanaka,Keisuke Tateishi,Tetsuo Ushiku,T. Hasegawa,Mitsuhiro Fujishiro +21 more
TL;DR: In this article , the authors investigated the long-term outcomes of intraductal papillary mucinous neoplasms (IPMNs) with MPD dilatation, and they found that those with the MPD = 5-9.9 mm had cumulative incidence rates of pancreatic carcinoma diagnosis of 8.1% (95% confidence interval [CI], 4.3-13.5%) and 10.0% ( 95% CI, 5.5-15.9%) at 2 and 5 years, respectively; and the patients with theMPD ≥10 mm had the corresponding rates of 16.0%.
Journal ArticleDOI
Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas
Jasmina Kuvendjiska,Felix Müller,Peter Bronsert,Sylvia Timme-Bronsert,Stefan Fichtner-Feigl,Birte Kulemann +5 more
TL;DR: In this article , size-based isolation of circulating epithelial cells (CECs) was performed on 27 patients with Intraductal Papillary Mucinous Neoplasm (IPMN) and showed a hybrid pattern of surface markers involving both epithelial and mesenchymal markers, suggesting a possible EMT process of the cells.
Journal ArticleDOI
Uncinate Duct Dilatation Predicts Additional Risk for High-Grade Dysplasia or Invasive Carcinoma Among Fukuoka-Positive Intraductal Papillary Mucinous Neoplasms
Alan Z. Yang,Sasiprang Kongboonvijit,Carlos Fernandez-del Castillo,Zhi Ven Fong,Piotr Zelga,Cristina R. Ferrone,Keith D. Lillemoe,Avinash K. Kambadakone,Motaz Qadan +8 more
TL;DR: In this paper , uncinate duct dilatation (UDD) was found to increase the risk of high grade dysplasia or invasive carcinoma (HGD/IC) in Fukuoka-positive intraductal papillary mucinous neoplasms (IPMNs).
Journal ArticleDOI
Intraductal Papillary Mucinous Neoplasm of the Pancreas: A Challenging Diagnosis
TL;DR: In this paper , the authors present recent imaging advances in the diagnosis and characterization of different types of IPMNs, as well as imaging tools available for early recognition of worrisome features for malignancy.
References
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Journal ArticleDOI
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Masao Tanaka,Carlos Fernandez-del Castillo,Volkan Adsay,Suresh T. Chari,Massimo Falconi,Jin-Young Jang,Wataru Kimura,Philippe Lévy,Martha B. Pitman,C. Max Schmidt,Michio Shimizu,Christopher L. Wolfgang,Koji Yamaguchi,Kenji Yamao +13 more
TL;DR: The present guidelines include recent information and recommendations based on the current understanding, and highlight issues that remain controversial and areas where further research is required.
Journal ArticleDOI
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Masao Tanaka,Suresh T. Chari,Volkan Adsay,Carlos Fernandez-del Castillo,Massimo Falconi,Michio Shimizu,Koji Yamaguchi,Kenji Yamao,Seiki Matsuno +8 more
TL;DR: Ovarian-type stroma has been proposed as a requisite to distinguish MCN from IPMN, and some other distinct features to characterize IPMN and MCN have been identified, but there remain ambiguities between the two diseases.
Journal ArticleDOI
Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.
William R. Brugge,Kent B. Lewandrowski,Elizabeth Lee-Lewandrowski,Barbara A. Centeno,Tara E. Szydlo,Susan Regan,Carlos Fernandez-del Castillo,Andrew L. Warshaw +7 more
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
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