Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
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TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
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Journal ArticleDOI
S6 ribosomal protein phosphorylation is associated with malignancy of intraductal papillary mucinous neoplasm of the pancreas.
Teijiro Hirashita,Yuka Hirashita,Yukio Iwashita,Yuichi Endo,Maki Kiyonaga,Shunro Matsumoto,Naoki Hijiya,Masatsugu Moriyama,Kazunari Murakami,Masafumi Inomata +9 more
TL;DR: The aim of this study was to investigate the role of S6 phosphorylation and the significance of glucose metabolic changes in IPMN.
Journal ArticleDOI
Pancreatic Cancer Surveillance: Who, When, and How.
Beth Dudley,Randall E. Brand +1 more
TL;DR: Current indications for PC surveillance are explored, as well as options for surveillance modality and timing, and data regarding surveillance outcomes suggest that individuals undergoing surveillance who develop PC are more likely to be diagnosed with resectable disease, which improves survival.
Journal ArticleDOI
Automated Detection of Pancreatic Cystic Lesions on CT Using Deep Learning.
Lorraine Abel,Jakob Wasserthal,Thomas Weikert,Alexander W. Sauter,Ivan Nesic,Marko Obradovic,Shan Yang,Sebastian Manneck,Carl G Glessgen,Johanna M. Ospel,Bram Stieltjes,Daniel T. Boll,Björn Friebe +12 more
TL;DR: In this paper, a two-step nnU-net architecture was proposed for automated detection of pancreatic cystic lesions on CT scans. But, the algorithm's performance was comparable to human readers and the number of false positive detections for cysts ≥ 220 mm3 was 0.1 per case.
Posted ContentDOI
Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection.
Ann Morgell,Julie A. Reisz,Zeeshan Ateeb,Haleh Davanian,Susanne E Reinsbach,Asif Halimi,Asif Halimi,Rogier Aäron Gaiser,Roberto Valente,Roberto Valente,Urban Arnelo,Urban Arnelo,Marco Del Chiaro,Margaret Chen,Angelo D'Alessandro +14 more
TL;DR: The validation of previous markers and identification of novel small molecule signatures of IPMN and disease progression further fuel the provoking debate as to whether bacterial infections may represent an etiological contributor to the development and severity of the disease in pancreatic cancer.
Journal ArticleDOI
McCune Albright syndrome is a genetic predisposition to intraductal papillary and mucinous neoplasms of the pancreas associated pancreatic cancer in relation with GNAS somatic mutation - a case report.
Sébastien Gaujoux,Eric Pasmant,Caroline Silve,Nadia Mehsen-Cetre,Romain Coriat,Alexandre Rouquette,Bertrand Douset,Bertrand Douset,Frédéric Prat,Karen Leroy +9 more
TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to foreign substance abuse.
References
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Journal ArticleDOI
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Masao Tanaka,Carlos Fernandez-del Castillo,Volkan Adsay,Suresh T. Chari,Massimo Falconi,Jin-Young Jang,Wataru Kimura,Philippe Lévy,Martha B. Pitman,C. Max Schmidt,Michio Shimizu,Christopher L. Wolfgang,Koji Yamaguchi,Kenji Yamao +13 more
TL;DR: The present guidelines include recent information and recommendations based on the current understanding, and highlight issues that remain controversial and areas where further research is required.
Journal ArticleDOI
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Masao Tanaka,Suresh T. Chari,Volkan Adsay,Carlos Fernandez-del Castillo,Massimo Falconi,Michio Shimizu,Koji Yamaguchi,Kenji Yamao,Seiki Matsuno +8 more
TL;DR: Ovarian-type stroma has been proposed as a requisite to distinguish MCN from IPMN, and some other distinct features to characterize IPMN and MCN have been identified, but there remain ambiguities between the two diseases.
Journal ArticleDOI
Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.
William R. Brugge,Kent B. Lewandrowski,Elizabeth Lee-Lewandrowski,Barbara A. Centeno,Tara E. Szydlo,Susan Regan,Carlos Fernandez-del Castillo,Andrew L. Warshaw +7 more
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
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