Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
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TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
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High-risk lesions in the remnant pancreas: fate of the remnant pancreas after pancreatic resection for pancreatic cancer and intraductal papillary mucinous neoplasms.
Yoshihiro Miyasaka,Yoshihiro Miyasaka,Takao Ohtsuka,Ryota Matsuda,Yasuhisa Mori,Kohei Nakata,Kenoki Ohuchida,Masafumi Nakamura +7 more
TL;DR: Although it is difficult to distinguish between local recurrence and a new primary lesion, comparison of genetic alterations between two lesions may help with this distinction, and life-long surveillance of the remnant pancreas is recommended after partial pancreatic resection for pancreatic cancer or IPMN.
Journal ArticleDOI
Advances in the management of pancreatic cystic neoplasms.
R. Matthew Walsh,Breanna Perlmutter,Volkan Adsay,Michelle D. Reid,Mark E. Baker,Tyler Stevens,Jonathan J. Hue,Jeffrey M. Hardacre,Gong-Qing Shen,Robert Simon,Essa M. Aleassa,Toms Augustin,Austin Eckhoff,Peter J. Allen,Brian K. P. Goh +14 more
Journal ArticleDOI
Diagnostic performance of current guidelines and postoperative outcome following surgical treatment of cystic pancreatic lesions - a 10-year single center experience.
Bojan Kovacevic,Mariana Fernanda Cordoba Hansen,Thomas S. Kristensen,John Gásdal Karstensen,Pia Klausen,Jan H Storkholm,Carsten Palnæs Hansen,Peter Vilmann +7 more
TL;DR: There is a need for new diagnostic tools and strategies in order to decrease the amount of overtreatment in patients with PCL, although European guidelines had a slightly higher mean specificity.
Journal ArticleDOI
Noninvasive risk stratification of intraductal papillary mucinous neoplasia with malignant potential by serum apolipoprotein-A2-isoforms.
Klaus Felix,Kazufumi Honda,Kengo Nagashima,Ayumi Kashiro,Keiko Takeuchi,Takashi Kobayashi,Sascha Hinterkopf,Matthias M. Gaida,Hien Dang,Niall Brindl,Jörg Kaiser,Markus W. Büchler,O. Strobel,O. Strobel +13 more
TL;DR: In this article, the concentrations of apoA2-i were retrospectively determined in 523 patient sera specimen, composed of 305 IPMNs with pre-invasive lesions with different grades of dysplasia and invasive cancer.
Journal ArticleDOI
A Comprehensive Review of the Current and Future Role of the Microbiome in Pancreatic Ductal Adenocarcinoma
Nabeel Merali,Tarak Chouari,Kayani Kayani,Carl J. Rayner,José I. Jiménez,Jonathan Krell,Elisa Giovannetti,Izhar Bagwan,Kate Relph,Timothy Rockall,Tony Dhillon,Hardev Pandha,Nicola E. Annels,Adam E Frampton +13 more
TL;DR: The role of the microbiome in PDAC and how it may alter survival outcomes is examined and the possibility of employing microbiomic signatures as biomarkers of PDAC is evaluated.
References
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Journal ArticleDOI
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Masao Tanaka,Carlos Fernandez-del Castillo,Volkan Adsay,Suresh T. Chari,Massimo Falconi,Jin-Young Jang,Wataru Kimura,Philippe Lévy,Martha B. Pitman,C. Max Schmidt,Michio Shimizu,Christopher L. Wolfgang,Koji Yamaguchi,Kenji Yamao +13 more
TL;DR: The present guidelines include recent information and recommendations based on the current understanding, and highlight issues that remain controversial and areas where further research is required.
Journal ArticleDOI
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Masao Tanaka,Suresh T. Chari,Volkan Adsay,Carlos Fernandez-del Castillo,Massimo Falconi,Michio Shimizu,Koji Yamaguchi,Kenji Yamao,Seiki Matsuno +8 more
TL;DR: Ovarian-type stroma has been proposed as a requisite to distinguish MCN from IPMN, and some other distinct features to characterize IPMN and MCN have been identified, but there remain ambiguities between the two diseases.
Journal ArticleDOI
Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.
William R. Brugge,Kent B. Lewandrowski,Elizabeth Lee-Lewandrowski,Barbara A. Centeno,Tara E. Szydlo,Susan Regan,Carlos Fernandez-del Castillo,Andrew L. Warshaw +7 more
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
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