Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
Reads0
Chats0
TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
Citations
More filters
Journal ArticleDOI
Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes
Andrew J McGuigan,Paul Kelly,Richard C. Turkington,C. Jones,Helen G. Coleman,R Stephen McCain +5 more
TL;DR: This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy.
Journal ArticleDOI
European evidence-based guidelines on pancreatic cystic neoplasms
Marco Del Chiaro,Marc G. Besselink,Lianne Scholten,Marco J. Bruno,Djuna L. Cahen,Thomas M. Gress,Jeanin E. van Hooft,Markus M. Lerch,Julia Mayerle,Thilo Hackert,Sohei Satoi,Alessandro Zerbi,David Cunningham,Claudio De Angelis,Marc Giovanni,Enrique de-Madaria,Péter Hegyi,Jonas Rosendahl,Helmut Friess,Riccardo Manfredi,Philippe Lévy,Francisco X. Real,Alain Sauvanet,Mohammed Abu Hilal,Giovanni Marchegiani,Irene Esposito,Paula Ghaneh,Marc R. W. Engelbrecht,Paul Fockens,Nadine C.M. van Huijgevoort,Christopher L. Wolfgang,Claudio Bassi,Natalya Gubergrits,Caroline S. Verbeke,Günter Klöppel,Aldo Scarpa,Giuseppe Zamboni,Anne Marie Lennon,Malin Sund,Nikolaos Kartalis,Lars Grenacher,Massimo Falconi,Urban Arnelo,Kostantin V. Kopchak,Kofi Oppong,Colin J. McKay,Truls Hauge,Kevin C. Conlon,Mustapha Adham,Güralp O. Ceyhan,Roberto Salvia,Christos Dervenis,Peter J. Allen,François Paye,Detlef K. Bartsch,Matthias Löhr,Massimiliano Mutignani,Johanna Laukkarinen,Richard D. Schulick,Roberto Valente,Thomas Seufferlein,Gabriele Capurso,Ajith K. Siriwardena,John P. Neoptolemos,Aldis Pukitis,Ralf Segersvärd,Ali A. Aghdassi,Stefano Andrianello,Peter Bossuyt,Robin Bülow,Karina Cárdenas-Jaén,P. Cortegoso,Martina Fontana,Lena Haeberle,M. Heckler,Andrey Litvin,Kulbir Mann,Christoph W. Michalski,Patrick Michl,Gennaro Nappo,Giampaolo Perri,S. Persson,F. Scheufele,Francesco Sclafani,Manuel Schmidt,L. Venezia,F. Volker,M-P Vullierm,L. Wusten +88 more
TL;DR: A conservative approach is recommended for asymptomatic MCN and IPMN, and Lifelong follow-up of IPMN is recommended in patients who are fit for surgery.
Journal ArticleDOI
Pancreatic adenocarcinoma, Version 2.2021
Margaret A. Tempero,Mokenge P. Malafa,Mahmoud M. Al-Hawary,Stephen W. Behrman,Al B. Benson,Dana Backlund Cardin,E. Gabriela Chiorean,Vincent Chung,Brian G. Czito,Marco Del Chiaro,Mary Dillhoff,Timothy R. Donahue,Efrat Dotan,Cristina R. Ferrone,Christos Fountzilas,Jeffrey M. Hardacre,William G. Hawkins,Kelsey Klute,Andrew H. Ko,John W. Kunstman,Noelle K. LoConte,Andrew M. Lowy,Cassadie Moravek,Eric K. Nakakura,Amol Narang,Jorge Obando,Patricio M. Polanco,Sushanth Reddy,Marsha Reyngold,Courtney L. Scaife,Jeanne Shen,Charles M. Vollmer,Robert A. Wolff,Brian M. Wolpin,Beth Lynn,Giby V. George +35 more
Abstract: Pancreatic cancer is the fourth leading cause of cancer-related death among men and women in the United States. A major challenge in treatment remains patients' advanced disease at diagnosis. The NCCN Guidelines for Pancreatic Adenocarcinoma provides recommendations for the diagnosis, evaluation, treatment, and follow-up for patients with pancreatic cancer. Although survival rates remain relatively unchanged, newer modalities of treatment, including targeted therapies, provide hope for improving patient outcomes. Sections of the manuscript have been updated to be concordant with the most recent update to the guidelines. This manuscript focuses on the available systemic therapy approaches, specifically the treatment options for locally advanced and metastatic disease.
Journal ArticleDOI
Early Detection of Pancreatic Cancer: Opportunities and Challenges
TL;DR: Current and emerging imaging modalities that are critical to identifying early, potentially curable PDAC in high-risk cohorts on surveillance are discussed.
Journal ArticleDOI
Single-Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression.
Vincent Bernard,Alexander Semaan,Jonathan Huang,F. Anthony San Lucas,Feven C Mulu,Bret M. Stephens,Paola A. Guerrero,Yanqing Huang,Jun Zhao,Nabiollah Kamyabi,Subrata Sen,Paul Scheet,Cullen M. Taniguchi,Michael P. Kim,Ching Wei D. Tzeng,Matthew Harold Katz,Aatur D. Singhi,Anirban Maitra,Hector A Alvarez +18 more
TL;DR: The ability to perform high-resolution profiling of the transcriptomic changes that occur during multistep progression of cystic PDAC precursors to cancer is demonstrated and might be a useful substrate to identify targets for cancer interception.
References
More filters
Journal ArticleDOI
Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreas
Thomas Schnelldorfer,Michael G. Sarr,David M. Nagorney,Lizhi Zhang,Thomas C. Smyrk,Rui Qin,Suresh T. Chari,Michael B. Farnell +7 more
TL;DR: Even with negative resection margins, the pancreatic remnant harbors a risk of recurrence and, thus, careful long-term surveillance is warranted.
Journal ArticleDOI
Branch duct intraductal papillary mucinous neoplasms: does cyst size change the tip of the scale? A critical analysis of the revised international consensus guidelines in a large single-institutional series.
Klaus Sahora,Mari Mino-Kenudson,William R. Brugge,Sarah P. Thayer,Cristina R. Ferrone,Dushyant V. Sahani,Martha B. Pitman,Andrew L. Warshaw,Keith D. Lillemoe,Carlos Fernandez-del Castillo +9 more
TL;DR: Expectant management of BD-IPMN following the old guidelines is safe, whereas caution is advised for larger lesions, even in the absence of worrisome features.
Journal ArticleDOI
Cystic neoplasm of the pancreas: a Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor.
Yutaka Suzuki,Yutaka Atomi,Masanori Sugiyama,Shuji Isaji,Kazuo Inui,Wataru Kimura,Makoto Sunamura,Toru Furukawa,Akio Yanagisawa,Akio Yanagisawa,Jo Ariyama,Tadahiro Takada,Hidenobu Watanabe,Koichi Suda +13 more
TL;DR: A multiinstitutional, retrospective study of 1379 cases of intraductal papillary mucinous tumor (IPMT) and 179 cases of mucinous cystic tumor (MCT) of the pancreas found IPMT and MCT show distinct clinicopathologic and prognostic differences.
Journal ArticleDOI
Intraductal Papillary-Mucinous Tumor of the Pancreas Concomitant with Ductal Carcinoma of the Pancreas
TL;DR: Clinicians should pay attention to the possible presence of DC of the pancreas in male patients with intraductal papillary-mucinous adenoma of the Pancreas of branch type in their 6th to 8th decades.
Journal ArticleDOI
Pancreatic Cysts: Pathologic Classification, Differential Diagnosis, and Clinical Implications
TL;DR: An overview of the current concepts in classification, differential diagnosis, and clinical/biologic behavior of pancreatic cystic tumors is provided.
Related Papers (5)
European evidence-based guidelines on pancreatic cystic neoplasms
Marco Del Chiaro,Marc G. Besselink,Lianne Scholten,Marco J. Bruno,Djuna L. Cahen,Thomas M. Gress,Jeanin E. van Hooft,Markus M. Lerch,Julia Mayerle,Thilo Hackert,Sohei Satoi,Alessandro Zerbi,David Cunningham,Claudio De Angelis,Marc Giovanni,Enrique de-Madaria,Péter Hegyi,Jonas Rosendahl,Helmut Friess,Riccardo Manfredi,Philippe Lévy,Francisco X. Real,Alain Sauvanet,Mohammed Abu Hilal,Giovanni Marchegiani,Irene Esposito,Paula Ghaneh,Marc R. W. Engelbrecht,Paul Fockens,Nadine C.M. van Huijgevoort,Christopher L. Wolfgang,Claudio Bassi,Natalya Gubergrits,Caroline S. Verbeke,Günter Klöppel,Aldo Scarpa,Giuseppe Zamboni,Anne Marie Lennon,Malin Sund,Nikolaos Kartalis,Lars Grenacher,Massimo Falconi,Urban Arnelo,Kostantin V. Kopchak,Kofi Oppong,Colin J. McKay,Truls Hauge,Kevin C. Conlon,Mustapha Adham,Güralp O. Ceyhan,Roberto Salvia,Christos Dervenis,Peter J. Allen,François Paye,Detlef K. Bartsch,Matthias Löhr,Massimiliano Mutignani,Johanna Laukkarinen,Richard D. Schulick,Roberto Valente,Thomas Seufferlein,Gabriele Capurso,Ajith K. Siriwardena,John P. Neoptolemos,Aldis Pukitis,Ralf Segersvärd,Ali A. Aghdassi,Stefano Andrianello,Peter Bossuyt,Robin Bülow,Karina Cárdenas-Jaén,P. Cortegoso,Martina Fontana,Lena Haeberle,M. Heckler,Andrey Litvin,Kulbir Mann,Christoph W. Michalski,Patrick Michl,Gennaro Nappo,Giampaolo Perri,S. Persson,F. Scheufele,Francesco Sclafani,Manuel Schmidt,L. Venezia,F. Volker,M-P Vullierm,L. Wusten +88 more
American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts.
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Olca Basturk,Seung-Mo Hong,Laura D. Wood,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Lodewijk A.A. Brosens,Noriyoshi Fukushima,Michael Goggins,Ralph H. Hruban,Yo Kato,David S. Klimstra,Günter Klöppel,Alyssa M. Krasinskas,Daniel S. Longnecker,Hanno Matthaei,G. Johan A. Offerhaus,Michio Shimizu,Kyoichi Takaori,Benoit Terris,Shinichi Yachida,Irene Esposito,Toru Furukawa +22 more