Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
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TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
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Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines
Nadine C.M. van Huijgevoort,Marco Del Chiaro,Christopher L. Wolfgang,Jeanin E. van Hooft,Marc G. Besselink +4 more
TL;DR: Uniform guidelines for diagnosis, treatment and follow-up of pancreatic cysts are urgently required and evidence on the best surveillance interval is lacking.
Journal ArticleDOI
Enrichment of Oral Microbiota in Early Cystic Precursors to Invasive Pancreatic Cancer
Rogier Aäron Gaiser,Asif Halimi,Hassan Alkharaan,Liyan Lu,Liyan Lu,Haleh Davanian,Katie Healy,Luisa W. Hugerth,Zeeshan Ateeb,Roberto Valente,Carlos Fernández Moro,Marco Del Chiaro,Margaret Chen,Margaret Chen +13 more
TL;DR: The findings warrant further investigation into the role of oral bacteria in cystic precursors to pancreatic cancer and have added values on the aetiopathology as well as the management of pancreatic cysts.
Journal ArticleDOI
Microbiota in pancreatic health and disease: the next frontier in microbiome research
Ryan M. Thomas,Christian Jobin +1 more
TL;DR: The authors examine the literature implicating microorganisms in diseases of the pancreas as well as the evidence of an inherent pancreatic microbiota to address pitfalls in the current literature and areas of investigation needed to advance a developing field of research.
Journal ArticleDOI
Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features
Yuko Omori,Yusuke Ono,Mishie Tanino,Hidenori Karasaki,Hiroshi Yamaguchi,Toru Furukawa,Katsuro Enomoto,Jun Ueda,Atsuko Sumi,Jin Katayama,Miho Muraki,Kenzui Taniue,Kuniyuki Takahashi,Yoshiyasu Ambo,Toshiya Shinohara,Hiroshi Nishihara,Junpei Sasajima,Hiroyuki Maguchi,Yusuke Mizukami,Toshikatsu Okumura,Shinya Tanaka +20 more
TL;DR: Detailed histologic and genetic analysis of PDAs and concurrent IPMNs identified 3 different pathways by which IPMNs progress to PDAs-the authors call these the sequential, branch-off, and de novo subtypes.
Journal ArticleDOI
Systematic review and meta-analysis: Prevalence of incidentally detected pancreatic cystic lesions in asymptomatic individuals.
Giulia Zerboni,Marianna Signoretti,Stefano Crippa,Massimo Falconi,Paolo Giorgio Arcidiacono,Gabriele Capurso +5 more
TL;DR: Mucinous lesions are the most common incidentally detected PCLs, although they rarely present with potential indication for surgery, and the observed different rates in the US and other geographic Areas suggest that different protocols might be necessary to help balancing costs and effectiveness of follow-up investigations in asymptomatic subjects.
References
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Journal ArticleDOI
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Masao Tanaka,Carlos Fernandez-del Castillo,Volkan Adsay,Suresh T. Chari,Massimo Falconi,Jin-Young Jang,Wataru Kimura,Philippe Lévy,Martha B. Pitman,C. Max Schmidt,Michio Shimizu,Christopher L. Wolfgang,Koji Yamaguchi,Kenji Yamao +13 more
TL;DR: The present guidelines include recent information and recommendations based on the current understanding, and highlight issues that remain controversial and areas where further research is required.
Journal ArticleDOI
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Masao Tanaka,Suresh T. Chari,Volkan Adsay,Carlos Fernandez-del Castillo,Massimo Falconi,Michio Shimizu,Koji Yamaguchi,Kenji Yamao,Seiki Matsuno +8 more
TL;DR: Ovarian-type stroma has been proposed as a requisite to distinguish MCN from IPMN, and some other distinct features to characterize IPMN and MCN have been identified, but there remain ambiguities between the two diseases.
Journal ArticleDOI
Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.
William R. Brugge,Kent B. Lewandrowski,Elizabeth Lee-Lewandrowski,Barbara A. Centeno,Tara E. Szydlo,Susan Regan,Carlos Fernandez-del Castillo,Andrew L. Warshaw +7 more
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
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