Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
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TLDR
The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.About:
This article is published in Pancreatology.The article was published on 2017-09-01. It has received 1104 citations till now.read more
Citations
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Iconographies supplémentaires de l'article : American Gastroenterological Association guidelines are inaccurate in detecting pancreatic cysts with advanced neoplasia: a clinicopathologic study of 225 patients with supporting molecular data
Aatur D. Singhi,Herbert J. Zeh,Randall E. Brand,Marina N. Nikiforova,Jennifer Chennat,Kenneth E. Fasanella,Asif Khalid,Georgios I. Papachristou,Adam Slivka,Melissa Hogg,Kenneth K. Lee,Allan Tsung,Amer H. Zureikat,Kevin McGrath +13 more
TL;DR: The AGA guidelines were inaccurate in detecting pancreatic cysts with advanced neoplasia and because the AGA guidelines manage all neoplastic cysts similarly, patients with SCAs will continue to undergo unnecessary MRI surveillance.
Journal ArticleDOI
A multimodality test to guide the management of patients with a pancreatic cyst
Simeon Springer,Simeon Springer,David L. Masica,Marco Dal Molin,Christopher Douville,Christopher J. Thoburn,Christopher J. Thoburn,Bahman Afsari,Lu Li,Lu Li,Joshua D. Cohen,Joshua D. Cohen,Elizabeth D. Thompson,Peter J. Allen,David S. Klimstra,Mark A. Schattner,C. Max Schmidt,Michele T. Yip-Schneider,Rachel E. Simpson,Carlos Fernandez-del Castillo,Mari Mino-Kenudson,William R. Brugge,Randall E. Brand,Aatur D. Singhi,Aldo Scarpa,Rita T. Lawlor,Roberto Salvia,Giuseppe Zamboni,Seung-Mo Hong,Dae Wook Hwang,Jin-Young Jang,Wooil Kwon,Niall Swan,Justin Geoghegan,Massimo Falconi,Stefano Crippa,Claudio Doglioni,Jorge Paulino,Richard D. Schulick,Barish H. Edil,Walter G. Park,Shinichi Yachida,Susumu Hijioka,Jeanin E. Van Hooft,Jin He,Matthew J. Weiss,Richard A. Burkhart,Martin A. Makary,Marcia I. Canto,Michael Goggins,Janine Ptak,Janine Ptak,Lisa Dobbyn,Lisa Dobbyn,Joy Schaefer,Joy Schaefer,Natalie Sillman,Natalie Sillman,Maria Popoli,Maria Popoli,Alison P. Klein,Alison P. Klein,Cristian Tomasetti,Rachel Karchin,Nickolas Papadopoulos,Nickolas Papadopoulos,Kenneth W. Kinzler,Kenneth W. Kinzler,Bert Vogelstein,Bert Vogelstein,Christopher L. Wolfgang,Ralph H. Hruban,Anne Marie Lennon +72 more
TL;DR: A machine-learning method that integrates high-dimensional clinical, imaging, and molecular data to diagnose and determine the likely best course of action for patients with pancreatic cysts found that clinical management informed by the CompCyst test was more accurate than the management dictated by conventional clinical and imaging criteria alone.
Journal ArticleDOI
Usefulness of Deep Learning Analysis for the Diagnosis of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas.
Takamichi Kuwahara,Kazuo Hara,Nobumasa Mizuno,Nozomi Okuno,Shimpei Matsumoto,Masahiro Obata,Yusuke Kurita,Hiroki Koda,Kazuhiro Toriyama,Sachiyo Onishi,Makoto Ishihara,Tsutomu Tanaka,Masahiro Tajika,Yasumasa Niwa +13 more
TL;DR: Artificial intelligence via deep learning algorithm may be a more accurate and objective method to diagnose malignancies of IPMNs in comparison to human diagnosis and conventional EUS features.
Posted ContentDOI
Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression
Vincent Bernard,Alexander Semaan,Jonathan Huang,F. Anthony San Lucas,Feven C Mulu,Bret M. Stephens,Paola A. Guerrero,Yanqing Huang,Jun Zhao,Nabiollah Kamyabi,Subrata Sen,Paul Scheet,Cullen M. Taniguchi,Michael P. Kim,Ching Wei D. Tzeng,Matthew Harold Katz,Aatur D. Singhi,Anirban Maitra,Hector A Alvarez +18 more
TL;DR: The ability to perform high resolution profiling of the transcriptomic changes that occur during multistep progression of cystic PDAC precursors to cancer is demonstrated and might be a useful substrate to identify targets for cancer interception.
Journal ArticleDOI
Pancreatic cancer: French clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, AFC)
Cindy Neuzillet,Sébastien Gaujoux,Nicolas Williet,Jean-Baptiste Bachet,Lucile Bauguion,Laurianne Colson Durand,Thierry Conroy,Laetitia Dahan,Marine Gilabert,Florence Huguet,Lysiane Marthey,Julie Meilleroux,Louis de Mestier,Bertrand Napoléon,Fabienne Portales,Antonio Sa Cunha,L. Schwarz,Julien Taieb,Benoist Chibaudel,Olivier Bouché,Pascal Hammel,Société Nationale Française de Gastroentérologie,Fédération Francophone de Cancérologie Digestive,Groupe Coopérateur multidisciplinaire en Oncologie,Fédération Nationale des Centres de Lutte Contre le Cancer,Société Française de Chirurgie Digestive,Société Française d’Endoscopie Digestive,Société Française de Radiothérapie Oncologique +27 more
TL;DR: These guidelines for management of PA are continuously evolving and need to be regularly updated, as each individual case is particular, they cannot substitute to multidisciplinary tumor board discussion.
References
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Journal ArticleDOI
International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas
Masao Tanaka,Carlos Fernandez-del Castillo,Volkan Adsay,Suresh T. Chari,Massimo Falconi,Jin-Young Jang,Wataru Kimura,Philippe Lévy,Martha B. Pitman,C. Max Schmidt,Michio Shimizu,Christopher L. Wolfgang,Koji Yamaguchi,Kenji Yamao +13 more
TL;DR: The present guidelines include recent information and recommendations based on the current understanding, and highlight issues that remain controversial and areas where further research is required.
Journal ArticleDOI
International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas.
Masao Tanaka,Suresh T. Chari,Volkan Adsay,Carlos Fernandez-del Castillo,Massimo Falconi,Michio Shimizu,Koji Yamaguchi,Kenji Yamao,Seiki Matsuno +8 more
TL;DR: Ovarian-type stroma has been proposed as a requisite to distinguish MCN from IPMN, and some other distinct features to characterize IPMN and MCN have been identified, but there remain ambiguities between the two diseases.
Journal ArticleDOI
Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study.
William R. Brugge,Kent B. Lewandrowski,Elizabeth Lee-Lewandrowski,Barbara A. Centeno,Tara E. Szydlo,Susan Regan,Carlos Fernandez-del Castillo,Andrew L. Warshaw +7 more
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
Journal ArticleDOI
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
Ralph H. Hruban,Kyoichi Takaori,David S. Klimstra,N. Volkan Adsay,Jorge Albores-Saavedra,Andrew V. Biankin,Sandra A. Biankin,Carolyn C. Compton,Noriyoshi Fukushima,Toru Furukawa,Michael Goggins,Yo Kato,Günter Klöppel,Daniel S. Longnecker,Jutta Lüttges,Anirban Maitra,G. Johan A. Offerhaus,Michio Shimizu,Suguru Yonezawa +18 more
TL;DR: The purpose of this meeting was to define an international acceptable set of diagnostic criteria for PanINs and IPMNs and to address a number of ambiguities that exist in the previously reported classification systems for these neoplasms.
Journal ArticleDOI
Increased Risk of Cancer in the Peutz–Jeghers Syndrome
Francis M. Giardiello,Steven B. Welsh,Stanley R. Hamilton,G. J. A. Offerhaus,A. M. Gittelsohn,Susan V. Booker,Anne J. Krush,John H. Yardley,Gordon D. Luk +8 more
TL;DR: It is suggested that patients with the Peutz-Jeghers syndrome have an increased risk for the development of cancer at gastrointestinal and nongastrointestinal sites.
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