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Sarcopenia: Revised European consensus on definition and diagnosis

TLDR
An emphasis is placed on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarc Openia diagnosis, and provides clear cut-off points for measurements of variables that identify and characterise sarc openia.
Abstract
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

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Quantitative features of intramuscular adipose tissue of the quadriceps and their association with gait independence in older inpatients: A cross-sectional study

TL;DR: The results from the present study suggested that intramuscular adipose tissue of the quadriceps of older inpatients was increased to ~1.7 times that of healthy older individuals matched for demographic characteristics.
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Sarcopenia and low muscle radiodensity associate with impaired FEV1 in allogeneic haematopoietic stem cell transplant recipients.

TL;DR: Quantification of skeletal muscle using computed tomography (CT) is accessible using cancer patients' standard oncologic images, and the impact of this on lung functional parameters is not characterized in adult allogeneic haematopoietic stem cell transplant (alloHCT) recipients.
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Sarcopenia is associated with non-alcoholic fatty liver disease in men with type 2 diabetes.

TL;DR: Sarcopenia is independently associated with non-alcoholic fatty liver disease in men with T2DM, which suggests that sarcopenia may be a risk factor for NAFLD in men without type 2 diabetes mellitus.
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Preoperative Treatment of Malnutrition and Sarcopenia in Cardiac Surgery: New Frontiers

TL;DR: Current evidence and potential effects of preoperative optimization of nutrition and physical status before cardiac surgery suggest that prehabilitation before elective surgery might be an opportunity to optimize the state of the patient.
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Malnutrition and sarcopenia are prevalent among inflammatory bowel disease patients with clinical remission.

TL;DR: A considerable proportion of IBD patients in clinical remission are revealed to be malnourished or at risk of malnutrition along with a high rate of sarcopenia, emphasizing the need for concomitant screening for nutritional status and body composition analysis in patients with IBD for provision of appropriate nutritional support, even during the remission period.
References
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Frailty in Older Adults Evidence for a Phenotype

TL;DR: This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition, and finds that there is an intermediate stage identifying those at high risk of frailty.
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The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons

TL;DR: This study evaluated a modified, timed version of the “Get‐Up and Go” Test (Mathias et al, 1986) in 60 patients referred to a Geriatric Day Hospital and suggested that the timed “Up & Go’ test is a reliable and valid test for quantifying functional mobility that may also be useful in following clinical change over time.
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Frailty in elderly people

TL;DR: Developing more efficient methods to detect frailty and measure its severity in routine clinical practice would greatly inform the appropriate selection of elderly people for invasive procedures or drug treatments and would be the basis for a shift in the care of frail elderly people towards more appropriate goal-directed care.
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