Sarcopenia: Revised European consensus on definition and diagnosis
Alfonso J. Cruz-Jentoft,Gulistan Bahat,Jürgen M. Bauer,Yves Boirie,Olivier Bruyère,Tommy Cederholm,Cyrus Cooper,Francesco Landi,Yves Rolland,Avan Aihie Sayer,Stéphane M. Schneider,Cornel C. Sieber,Eva Topinkova,Maurits Vandewoude,Marjolein Visser,Mauro Zamboni +15 more
TLDR
An emphasis is placed on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarc Openia diagnosis, and provides clear cut-off points for measurements of variables that identify and characterise sarc openia.Abstract:
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.read more
Citations
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Impact of using the updated EWGSOP2 definition in diagnosing sarcopenia: A clinical perspective.
Jeanine M. Van Ancum,Julian Alcazar,Julian Alcazar,Carel G. M. Meskers,Barbara Rubæk Nielsen,Charlotte Suetta,Andrea B. Maier +6 more
TL;DR: The prevalence of sarcopenia in males is significantly lower compared to the EWGSOP definition, whereas the prevalence among women is slightly higher, and the lower cut-off points for handgrip strength result in fewer adults being diagnosed with sarc Openia.
Journal ArticleDOI
Sarcopenia and peripheral arterial disease: a systematic review
Mégane Pizzimenti,Alain Meyer,Anne-Laure Charles,Margherita Giannini,Nabil Chakfe,Anne Lejay,Bernard Geny +6 more
TL;DR: Sarcopenia and lower extremity PAD have musculoskeletal consequences that directly impair patients' quality of life and prognosis and approaches targeting the underlying mechanisms still deserve further studies.
Journal ArticleDOI
Mouse models of sarcopenia: classification and evaluation
TL;DR: A review of mouse models that can be used in the study of sarcopenia can be found in this paper, including ageing models, genetically engineered models, hindlimb suspension models, chemical induction models, denervation models, and immobilization models.
Journal ArticleDOI
Association between dietary nutrient intake and sarcopenia in the SarcoPhAge study
TL;DR: The results suggest that a poorly balanced diet may be associated with sarcopenia and poor musculoskeletal health, although prospective studies are needed to confirm these findings.
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Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
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