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Sarcopenia: Revised European consensus on definition and diagnosis

TLDR
An emphasis is placed on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarc Openia diagnosis, and provides clear cut-off points for measurements of variables that identify and characterise sarc openia.
Abstract
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

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Sarcopenia

Yu-fei Li, +1 more
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Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association.

TL;DR: Evidence is provided to support recommendations for successful resistance training in older adults related to 4 parts: program design variables, physiological adaptations, functional benefits, and considerations for frailty, sarcopenia, and other chronic conditions.
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International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management

Elsa Dent, +38 more
TL;DR: Evidence-based clinical practice guidelines for screening, diagnosis and management of sarcopenia from the task force of the International Conference on Sarcopenia and Frailty Research (ICSFR) are presented.
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Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis

TL;DR: The positive association between sarcopenia with falls and fractures in older adults strengthens the need to invest in sarc Openia prevention and interventions to evaluate its effect on falls and fracture.
References
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Journal ArticleDOI

Investigation into the reliability and validity of the measurement of elderly people's clinical walking speed: A systematic review

TL;DR: Both habitual and maximum walking speeds are valid instruments, and they predict death, hospitalization/institutionalization, and decline in mobility.
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Clinical outcomes related to muscle mass in humans with cancer and catabolic illnesses

TL;DR: This review discusses the emergence of muscle mass measurement using diagnostic imaging and the relationship between muscle mass and clinical outcome, and the efficacy of different therapies developed for the treatment of muscle wasting.
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Performance of SARC-F in Regard to Sarcopenia Definitions, Muscle Mass and Functional Measures.

TL;DR: The findings suggest that SARC-F is an excellent test to exclude muscle function impairment and sarcopenia and is relatively a good screening test for functional measures.
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Relation between whole-body and regional measures of human skeletal muscle

TL;DR: Although thigh measures of SM are better predictors of whole-body SM, a single image within the abdomen routinely used to estimate abdominal fat may also be a useful marker of whole -body SM.
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The multiple dimensions of frailty: physical capacity, cognition, and quality of life.

TL;DR: In addition to the reduced physical capacity, frailty might affect selective components of cognition and quality of life, which should be investigated in intervention programs designed for frail older adults.
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