Sarcopenia: Revised European consensus on definition and diagnosis
Alfonso J. Cruz-Jentoft,Gulistan Bahat,Jürgen M. Bauer,Yves Boirie,Olivier Bruyère,Tommy Cederholm,Cyrus Cooper,Francesco Landi,Yves Rolland,Avan Aihie Sayer,Stéphane M. Schneider,Cornel C. Sieber,Eva Topinkova,Maurits Vandewoude,Marjolein Visser,Mauro Zamboni +15 more
TLDR
An emphasis is placed on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarc Openia diagnosis, and provides clear cut-off points for measurements of variables that identify and characterise sarc openia.Abstract:
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.read more
Citations
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Assessment of Malnutrition, Sarcopenia and Frailty in Patients with Cirrhosis: Which Tools Should We Use in Clinical Practice?
TL;DR: The definition of malnutrition was adapted to patients with cirrhosis based on the assessment of sarcopenia together with reduced food intakes and the relevance of frailty and sarc Openia in the course of liver diseases was shown.
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Sarcopenia: Current treatments and new regenerative therapeutic approaches
TL;DR: A review of the potential pros and cons associated with various stem cell types/secretome in sarcopenia treatment and the regulatory and production barriers that need to be overcome to translate such novel therapeutic agents into bedside application and propose therapeutic potential of stem cell therapy and bioactive secretome for sarc Openia.
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Guidance for assessment of the muscle mass phenotypic criterion for the Global Leadership Initiative on Malnutrition (GLIM) diagnosis of malnutrition.
Rocco Barazzoni,Gordon L. Jensen,Maria Isabel Toulson Davisson Correia,María Cristina González,Takashi Higashiguchi,Han Ping Shi,Stephan C. Bischoff,Yves Boirie,Fernando Carrasco,Alfonso J. Cruz-Jentoft,Vanessa Fuchs-Tarlovsky,Ryoji Fukushima,Steven B. Heymsfield,Marina Mourtzakis,Maurizio Muscaritoli,Kristina Norman,Ibolya Nyulasi,Veeradej Pisprasert,Carla M. Prado,Marian de van der Schuren,Sadao Yoshida,Yanchun Yu,Tommy Cederholm,Charlene Compher +23 more
TL;DR: The Global Leadership Initiative on Malnutrition (GLIM) provides consensus criteria for the diagnosis of malnutrition that can be widely applied as discussed by the authors , which is based on the assessment of three phenotypic (weight loss, low body mass index, and low skeletal muscle mass) and two etiologic (low food intake and presence of disease with systemic inflammation).
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Calf circumference: cutoff values from the NHANES 1999-2006.
Maria Cristina Gonzalez,Maria Cristina Gonzalez,Ali Mehrnezhad,Nariman Razaviarab,Thiago G Barbosa-Silva,Steven B. Heymsfield +5 more
TL;DR: In this paper, the authors developed CC cutoff points and identified relevant confounding factors from the large and diverse NHANES 1999-2006 population sample, and used these cutoff points to diagnose low skeletal muscle (SM) and sarcopenia.
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Physical activity guidelines for older people: knowledge gaps and future directions
TL;DR: It is essential to help health-care systems to more efficiently implement evidence-based exercise programmes for frail older adults in all community and care settings to promote healthy and dignified ageing.
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Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
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