Sarcopenia: Revised European consensus on definition and diagnosis
Alfonso J. Cruz-Jentoft,Gulistan Bahat,Jürgen M. Bauer,Yves Boirie,Olivier Bruyère,Tommy Cederholm,Cyrus Cooper,Francesco Landi,Yves Rolland,Avan Aihie Sayer,Stéphane M. Schneider,Cornel C. Sieber,Eva Topinkova,Maurits Vandewoude,Marjolein Visser,Mauro Zamboni +15 more
TLDR
An emphasis is placed on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarc Openia diagnosis, and provides clear cut-off points for measurements of variables that identify and characterise sarc openia.Abstract:
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.read more
Citations
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Muscle Wasting and Sarcopenia in Heart Failure—The Current State of Science
TL;DR: The purpose of this review is to illustrate the current knowledge in terms of pathogenesis, diagnosis, and treatment of sarcopenia in order to provide a better understanding of wasting disorders occurring in chronic heart failure.
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Handgrip Strength Asymmetry and Weakness Are Associated with Lower Cognitive Function: A Panel Study.
Ryan McGrath,Peggy M. Cawthon,Peggy M. Cawthon,Matteo Cesari,Matteo Cesari,Soham Al Snih,Brian C. Clark +6 more
TL;DR: The purpose of this study was to determine the associations of HGS asymmetry and weakness on lower cognitive functioning in a national sample of aging Americans.
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Prevalence and Associated Factors of Sarcopenia in Singaporean Adults-The Yishun Study.
Benedict Wei Jun Pang,Shiou Liang Wee,Lay Khoon Lau,Khalid Abdul Jabbar,Wei Ting Seah,Daniella Hui Min Ng,Queenie Lin Ling Tan,Kenneth Kexun Chen,Mallya Ullal Jagadish,Tze Pin Ng +9 more
TL;DR: This is the first study to provide reference values of muscle mass, strength, and gait speed across the adult lifespan of Singaporeans, and indicates sarcopenia is prominent in older age, but it is already nontrivial among young and middle-age persons.
Journal ArticleDOI
The Gut-Muscle Axis in Older Subjects with Low Muscle Mass and Performance: A Proof of Concept Study Exploring Fecal Microbiota Composition and Function with Shotgun Metagenomics Sequencing.
Andrea Ticinesi,Leonardo Mancabelli,Sara Tagliaferri,Antonio Nouvenne,Christian Milani,Daniele Del Rio,Fulvio Lauretani,Marcello Maggio,Marco Ventura,Tiziana Meschi +9 more
TL;DR: The hypothesis of an association between microbiota and sarcopenia is supported, indicating novel possible mediators, whose clinical relevance should be investigated in future studies.
Journal ArticleDOI
Comparison of revised EWGSOP criteria and four other diagnostic criteria of sarcopenia in Chinese community-dwelling elderly residents.
Lei Yang,Xuemei Yao,Jing Shen,Gaofeng Sun,Qi Sun,Xiaoli Tian,Xiaoxia Li,Xue Li,Ledan Ye,Zhanlin Zhang,Jianghong Dai,Hui Xiao +11 more
TL;DR: The EW GSOP2 criteria did not agree with the EWGSOP1, AWGS, IWGA, and FNIH criteria defining sarcopenia, and risk factors associated with theEWGSOP2-defined sarc Openia have no consistent patterns with the Eagle Group on Sarcopenia in Older People criteria.
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Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
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