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Anders Mellemgaard
Researcher at Copenhagen University Hospital
Publications - 93
Citations - 8215
Anders Mellemgaard is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 35, co-authored 88 publications receiving 7569 citations.
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Journal ArticleDOI
Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer
Giorgio V. Scagliotti,Purvish M. Parikh,Joachim von Pawel,Bonne Biesma,Johan Vansteenkiste,Christian Manegold,Piotr Serwatowski,Ulrich Gatzemeier,Raghunadharao Digumarti,Mauro Zukin,Jin S. Lee,Anders Mellemgaard,Keunchil Park,Shehkar Patil,Janusz Rolski,Tuncay Göksel,Filippo de Marinis,Lorinda Simms,Katherine P. Sugarman,David R. Gandara +19 more
TL;DR: This is the first prospective phase III study in NSCLC to show survival differences based on histologic type and cisplatin/pemetrexed provides similar efficacy with better tolerability and more convenient administration than cis platin/gemcitabine.
Journal ArticleDOI
Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial
Martin Reck,Rolf Kaiser,Anders Mellemgaard,Jean-Yves Douillard,Sergey Orlov,Maciej Krzakowski,Joachim von Pawel,Maya Gottfried,Igor Bondarenko,Meilin Liao,Claudia-Nanette Gann,José Barrueco,Birgit Gaschler-Markefski,Silvia Novello +13 more
TL;DR: Overall survival was significantly improved for patients with adenocarcinoma histology who progressed within 9 months after start of first-line treatment in the docetaxel plus nintedanib group, compared with those in theDocetaxe plus placebo group.
Journal ArticleDOI
Obesity and cancer risk: a danish record-linkage study
TL;DR: Overall, the incidence of cancer was increased by 16% in the cohort and the results were essentially unchanged by restriction to the subcohort of 8207 persons in whom obesity was the primary discharge diagnosis, and were also similar in the first year of follow-up after hospital discharge.
Journal ArticleDOI
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
James D. McKay,Rayjean J. Hung,Younghun Han,Xuchen Zong,Robert Carreras-Torres,David C. Christiani,Neil E. Caporaso,Mattias Johansson,Xiangjun Xiao,Yafang Li,Jinyoung Byun,Alison M. Dunning,Karen A. Pooley,David C. Qian,Xuemei Ji,Geoffrey Liu,Maria Timofeeva,Stig E. Bojesen,Stig E. Bojesen,Stig E. Bojesen,Xifeng Wu,Loic Le Marchand,Demetrios Albanes,Heike Bickeböller,Melinda C. Aldrich,William S. Bush,Adonina Tardón,Gad Rennert,M. Dawn Teare,John K. Field,Lambertus A. Kiemeney,Philip Lazarus,Aage Haugen,Stephen Lam,Matthew B. Schabath,Angeline S. Andrew,Hongbing Shen,Yun Chul Hong,Jian-Min Yuan,Pier Alberto Bertazzi,Angela Cecilia Pesatori,Yuanqing Ye,Nancy Diao,Li Su,Ruyang Zhang,Yonathan Brhane,Natasha B. Leighl,Jakob S Johansen,Anders Mellemgaard,Walid Saliba,Christopher A. Haiman,Lynne R. Wilkens,Ana Fernández-Somoano,Guillermo Fernández-Tardón,Henricus F. M. van der Heijden,Jin Hee Kim,Juncheng Dai,Zhibin Hu,Michael P.A. Davies,Michael W. Marcus,Hans Brunnström,Jonas Manjer,Olle Melander,David C. Muller,Kim Overvad,Antonia Trichopoulou,Rosario Tumino,Jennifer A. Doherty,Matt P Barnett,Chu Chen,Gary E. Goodman,Angela Cox,Fiona Taylor,Penella J. Woll,Irene Brüske,H-Erich Wichmann,H-Erich Wichmann,Judith Manz,Thomas Muley,Angela Risch,Albert Rosenberger,Kjell Grankvist,Mikael Johansson,Frances A. Shepherd,Ming-Sound Tsao,Susanne M. Arnold,Eric B. Haura,Ciprian Bolca,Ivana Holcatova,Vladimir Janout,Milica Kontic,Jolanta Lissowska,Anush Mukeria,Simona Ognjanovic,Tadeusz M Orlowski,Ghislaine Scelo,Beata Swiatkowska,David Zaridze,Per Bakke,Vidar Skaug,Shanbeh Zienolddiny,Eric J. Duell,Lesley M. Butler,Woon-Puay Koh,Yu-Tang Gao,Richard S. Houlston,John McLaughlin,Victoria L. Stevens,Philippe Joubert,Maxime Lamontagne,David C. Nickle,Ma'en Obeidat,Wim Timens,Bin Zhu,Lei Song,Linda Kachuri,María Soler Artigas,María Soler Artigas,Martin D. Tobin,Martin D. Tobin,Louise V. Wain,Louise V. Wain,Thorunn Rafnar,Thorgeir E. Thorgeirsson,Gunnar W Reginsson,Kari Stefansson,Dana B. Hancock,Laura J. Bierut,Margaret R. Spitz,Nathan C. Gaddis,Sharon M. Lutz,Fangyi Gu,Eric O. Johnson,Ahsan Kamal,Claudio W. Pikielny,Dakai Zhu,Sara Lindstroem,Xia Jiang,Rachel F. Tyndale,Rachel F. Tyndale,Georgia Chenevix-Trench,Jonathan Beesley,Yohan Bossé,Stephen J. Chanock,Paul Brennan,Maria Teresa Landi,Christopher I. Amos +146 more
TL;DR: 18 susceptibility loci achieving genome-wide significance are identified, including 10 new loci linked with lung cancer overall and six loci associated with lung adenocarcinoma, highlighting the striking heterogeneity in genetic susceptibility across the histological subtypes of lung cancer.
Journal ArticleDOI
Age at first birth, parity and risk of breast cancer: a meta-analysis of 8 studies from the Nordic countries.
Marianne Ewertz,Stephen W. Duffy,Hans-Olov Adami,Gunnar Kvåle,Eiliv Lund,O. Meirik,Anders Mellemgaard,Irma Soini,Hrafn Tulinius +8 more
TL;DR: A meta‐analysis of population‐based studies of breast cancer and reproductive variables in the Nordic countries confirmed that low parity and late age at first birth are significant and independent determinants of breast‐cancer risk, and suggested that several individual Nordic studies may have had too little power to detect the weak effect of age atFirst birth observed in the meta-analysis.