B
Barbara Heude
Researcher at University of Paris
Publications - 291
Citations - 14729
Barbara Heude is an academic researcher from University of Paris. The author has contributed to research in topics: Pregnancy & Medicine. The author has an hindex of 46, co-authored 224 publications receiving 11672 citations. Previous affiliations of Barbara Heude include Harvard University & University of Oviedo.
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Journal ArticleDOI
A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek,Ghislain Rocheleau,Johan Rung,Christian Dina,Lishuang Shen,David Serre,Philippe Boutin,Daniel Vincent,Alexandre Belisle,Samy Hadjadj,Beverley Balkau,Barbara Heude,Guillaume Charpentier,Thomas J. Hudson,Thomas J. Hudson,Alexandre Montpetit,Alexey V. Pshezhetsky,Marc Prentki,Barry I. Posner,David J. Balding,David Meyre,Constantin Polychronakos,Philippe Froguel,Philippe Froguel +23 more
TL;DR: Four loci containing variants that confer type 2 diabetes risk are identified and constitute proof of principle for the genome-wide approach to the elucidation of complex genetic traits.
Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
David Meyre,Jérôme Delplanque,Jean-Claude Chèvre,Cécile Lecoeur,Stéphane Lobbens,Sophie Gallina,Emmanuelle Durand,Vincent Vatin,Franck Degraeve,Christine Proença,Stefan Gaget,Antje Körner,Peter Kovacs,Wieland Kiess,Jean Tichet,Michel Marre,Anna-Liisa Hartikainen,Fritz F. Horber,Natascha Potoczna,Serge Hercberg,Claire Levy-Marchal,Claire Levy-Marchal,François Pattou,Barbara Heude,Maithé Tauber,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Alexandra I. F. Blakemore,Alexandre Montpetit,Constantin Polychronakos,Jacques Weill,Lachlan J. M. Coin,Julian E. Asher,Paul Elliott,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Sophie Visvikis-Siest,Beverley Balkau,Robert Sladek,David J. Balding,Andrew Walley,Christian Dina,Philippe Froguel,Philippe Froguel +44 more
TL;DR: In addition to FTO and MC4R, genome-wide association data from 1,380 Europeans with early-onset and morbid adult obesity and 1,416 age-matched normal-weight controls detected significant association of obesity with three new risk loci in NPC1, near MAF and near PTER.
Journal ArticleDOI
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
Nabila Bouatia-Naji,Amélie Bonnefond,Amélie Bonnefond,Christine Cavalcanti-Proença,Christine Cavalcanti-Proença,Thomas Sparsø,Johan Holmkvist,Marion Marchand,Marion Marchand,Jérôme Delplanque,Jérôme Delplanque,Stéphane Lobbens,Stéphane Lobbens,Ghislain Rocheleau,Emmanuelle Durand,Emmanuelle Durand,Franck De Graeve,Franck De Graeve,Jean-Claude Chèvre,Jean-Claude Chèvre,Knut Borch-Johnsen,Anna-Liisa Hartikainen,Aimo Ruokonen,Jean Tichet,Michel Marre,Michel Marre,Jacques Weill,Barbara Heude,Barbara Heude,Maithé Tauber,Katleen Lemaire,Frans Schuit,Paul Elliott,Torben Jørgensen,Guillaume Charpentier,Samy Hadjadj,Stéphane Cauchi,Stéphane Cauchi,Martine Vaxillaire,Martine Vaxillaire,Robert Sladek,Sophie Visvikis-Siest,Beverley Balkau,Beverley Balkau,Claire Levy-Marchal,Claire Levy-Marchal,François Pattou,David Meyre,David Meyre,Alexandra I. F. Blakemore,M. R. Järvelin,M. R. Järvelin,Andrew Walley,Torben Hansen,Christian Dina,Christian Dina,Oluf Pedersen,Oluf Pedersen,Philippe Froguel,Philippe Froguel,Philippe Froguel +60 more
TL;DR: The data suggest a possible link between circadian rhythm regulation and glucose homeostasis through the melatonin signaling pathway and show MT2 expression in human pancreatic islets and beta cells.
Journal ArticleDOI
Ambient air pollution and low birthweight: a European cohort study (ESCAPE)
Marie Pedersen,Lise Giorgis-Allemand,Claire Bernard,Inmaculada Aguilera,Anne-Marie Nybo Andersen,Ferran Ballester,Rob Beelen,Leda Chatzi,Marta Cirach,Asta Danileviciute,Audrius Dedele,Manon van Eijsden,Marisa Estarlich,Ana Fernández-Somoano,Mariana F. Fernández,Francesco Forastiere,Ulrike Gehring,Regina Grazuleviciene,Olena Gruzieva,Barbara Heude,Barbara Heude,Gerard Hoek,Kees de Hoogh,Edith H. van den Hooven,Siri E. Håberg,Vincent W. V. Jaddoe,Claudia Klümper,Michal Korek,Ursula Krämer,Aitana Lerchundi,Johanna Lepeule,Johanna Lepeule,Per Nafstad,Wenche Nystad,Evridiki Patelarou,Evridiki Patelarou,Daniela Porta,Dirkje S. Postma,Ole Raaschou-Nielsen,Peter Rudnai,Jordi Sunyer,Euripides G. Stephanou,Mette Sørensen,Elisabeth Thiering,Derek Tuffnell,Mihály J. Varró,Tanja G. M. Vrijkotte,Alet H. Wijga,Michael Wilhelm,John Wright,Mark J. Nieuwenhuijsen,Göran Pershagen,Göran Pershagen,Bert Brunekreef,Bert Brunekreef,Manolis Kogevinas,Rémy Slama +56 more
TL;DR: Exposure to ambient air pollutants and traffic during pregnancy is associated with restricted fetal growth and a substantial proportion of cases of low birthweight at term could be prevented in Europe if urban air pollution was reduced.