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Corinne Miceli-Richard

Researcher at University of Paris-Sud

Publications -  117
Citations -  6821

Corinne Miceli-Richard is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Rheumatoid arthritis & B-cell activating factor. The author has an hindex of 41, co-authored 100 publications receiving 5905 citations. Previous affiliations of Corinne Miceli-Richard include French Institute of Health and Medical Research & Université Paris-Saclay.

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Journal ArticleDOI

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Yukinori Okada, +115 more
- 20 Feb 2014 - 
TL;DR: A genome-wide association study meta-analysis in a total of >100,000 subjects of European and Asian ancestries provides empirical evidence that the genetics of RA can provide important information for drug discovery, and sheds light on fundamental genes, pathways and cell types that contribute to RA pathogenesis.
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Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

Christopher J. Lessard, +67 more
- 01 Nov 2013 - 
TL;DR: The results highlight the importance of genes that are involved in both innate and adaptive immunity in Sjögren's syndrome, including TNFAIP3, PTTG1, PRDM1, DGKQ, FCGR2A, IRAK1BP1, ITSN2 and PHIP, among others.
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B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome.

TL;DR: Demonstrating the capacity of SGECs to express and secrete BAFF after IFN stimulation adds further information to the pivotal role of these epithelial cells in the pathogenesis of pSS, possibly after stimulation by innate immunity.
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Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndrome.

TL;DR: BAFF may be expressed by T cells at the site of autoimmune damage and could play a role in the pathogenesis of pSS, particularly by triggering the activation of self‐antigen‐driven autoimmune B cells.
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Association of an IRF5 gene functional polymorphism with Sjögren's syndrome.

TL;DR: This study is the first to demonstrate a significant association between primary SS and the IRF5 rs2004640 T allele, and suggests that primarySS and SLE share IRF gene polymorphisms as a common genetic susceptibility factor.