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Erwin W. Gelfand
Researcher at University of Colorado Denver
Publications - 679
Citations - 37565
Erwin W. Gelfand is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Immunoglobulin E & T cell. The author has an hindex of 99, co-authored 675 publications receiving 36059 citations. Previous affiliations of Erwin W. Gelfand include University of Colorado Hospital & University of Virginia.
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Journal ArticleDOI
Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography
Eckard Hamelmann,Jürgen Schwarze,Katsuyuki Takeda,A. Oshiba,Gary L. Larsen,Charles G. Irvin,Erwin W. Gelfand +6 more
TL;DR: Measurement of AR to inhaled methacholine by barometric whole-body plethysmography is a valid indicator of airway hyperresponsiveness after allergic sensitization in mice, and it is shown that AR measured as Penh was associated with increased IgE production and eosinophil lung infiltration.
Journal ArticleDOI
Vβ-specific stimulation of human T cells by staphylococcal toxins
John W. Kappler,Brian L. Kotzin,Lynne Herron,Erwin W. Gelfand,Robert D. Bigler,Arthur Boylston,Stefan Carrel,David N. Posnett,Yongwon Choi,Philippa Marrack +9 more
TL;DR: The specificity of these toxins for V beta s puts them in the recently described class of superantigens and may account for the differential sensitivity of different individuals to the toxic effects of these proteins.
Journal ArticleDOI
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
TL;DR: Accumulating evidence is reviewed suggesting that histamine indeed has roles in inflammation and immune function modulation in such diseases and a possible synergy between H1 and H4-receptor antagonists in targeting various inflammatory conditions is reviewed.
Journal ArticleDOI
Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States
Antonia Kwan,Roshini S. Abraham,Robert Currier,Amy Brower,Karen Andruszewski,Jordan K. Abbott,Mei W. Baker,Mark Ballow,Louis Bartoshesky,Francisco A. Bonilla,Charles D. Brokopp,Edward G. Brooks,Michele Caggana,Jocelyn Celestin,Joseph A. Church,Anne Marie Comeau,James A. Connelly,Morton J. Cowan,Charlotte Cunningham-Rundles,Trivikram Dasu,Nina Dave,Maria Teresa de la Morena,Ulrich A. Duffner,Chin-To Fong,Lisa R. Forbes,Lisa R. Forbes,Debra Freedenberg,Erwin W. Gelfand,Jaime E. Hale,I. Celine Hanson,I. Celine Hanson,Beverly N. Hay,Diana Hu,Anthony J. Infante,Daisy Johnson,Neena Kapoor,Denise M. Kay,Donald B. Kohn,Rachel Lee,Heather K. Lehman,Zhili Lin,Fred Lorey,Aly Abdel-Mageed,Adrienne Manning,Sean A. McGhee,Sean A. McGhee,Theodore B. Moore,Stanley J. Naides,Luigi D. Notarangelo,Jordan S. Orange,Jordan S. Orange,Sung-Yun Pai,Matthew H. Porteus,Matthew H. Porteus,Ray Rodriguez,Neil Romberg,John M. Routes,Mary Ruehle,Arye Rubenstein,Carlos A. Saavedra-Matiz,Ginger Scott,Patricia M. Scott,Elizabeth Secord,Christine M. Seroogy,William T. Shearer,William T. Shearer,Subhadra Siegel,Stacy K. Silvers,E. Richard Stiehm,Robert W. Sugerman,John L. Sullivan,Susan Tanksley,Millard L. Tierce,James W. Verbsky,Beth Vogel,Rosalyn Walker,Kelly Walkovich,Jolan E. Walter,Richard L. Wasserman,Michael S. Watson,Geoffrey A. Weinberg,Leonard B. Weiner,Heather Wood,Anne B. Yates,Jennifer M. Puck +84 more
TL;DR: Newborn screening in 11 programs in the United States identified SCID in 1 in 58,000 infants, with high survival, and the usefulness of detection of non-SCID T-cell lymphopenia by the same screening remains to be determined.
Journal ArticleDOI
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma.
James J. Lee,Michael P. McGarry,S. Farmer,Karen L. Denzler,Kirsten A. Larson,Patricia E. Carrigan,I Brenneise,Margaret A. Horton,Angela Franciska Haczku,Erwin W. Gelfand,George D. Leikauf,Nancy A. Lee +11 more
TL;DR: It is demonstrated that lung-specific IL-5 expression can induce pathologic changes characteristic of asthma and may provide useful models to evaluate the efficacy of potential respiratory disease therapies or pharmaceuticals.