J
Janine Altmueller
Researcher at University of Cologne
Publications - 35
Citations - 2212
Janine Altmueller is an academic researcher from University of Cologne. The author has contributed to research in topics: Cancer & Exome sequencing. The author has an hindex of 16, co-authored 35 publications receiving 1454 citations. Previous affiliations of Janine Altmueller include Max Delbrück Center for Molecular Medicine & Charité.
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Journal ArticleDOI
A genomics-based classification of human lung tumors
Danila Seidel,Thomas Zander,Lukas C. Heukamp,Martin Peifer,Marc Bos,Lynnette Fernandez-Cuesta,Frauke Leenders,Xin Lu,Sascha Ansén,Masyar Gardizi,Chau Nguyen,Chau Nguyen,Johannes Berg,Prudence A. Russell,Zoe Wainer,Hans-Ulrich Schildhaus,Hans-Ulrich Schildhaus,Toni-Maree Rogers,Benjamin Solomon,William Pao,Scott L. Carter,Gad Getz,D. Neil Hayes,Matthew D. Wilkerson,Erik Thunnissen,William D. Travis,Sven Perner,Gavin M. Wright,Elisabeth Brambilla,Reinhard Buettner,Juergen Wolf,Roman K. Thomas,Franziska Gabler,Ines Wilkening,Christian Mueller,Ilona Dahmen,Roopika Menon,Katharina Koenig,Kerstin Albus,Sabine Merkelbach-Bruse,Jana Fassunke,Katja Schmitz,Helen Kuenstlinger,Michaela Angelika Kleine,Elke Binot,Silvia Querings,Janine Altmueller,Ingelore Boessmann,Peter Nuemberg,Peter M. Schneider,Magdalena Bogus,Alex Soltermann,Holger Moch,Odd Terje Brustugun,Steinar Solberg,Marius Lund-Iversen,Åslaug Helland,Thomas Muley,Hans Hoffmann,Philipp A. Schnabel,Yuan Chen,Harry J.M. Groen,Wim Timens,Hannie Sietsma,Joachim H. Clement,Walter Weder,Joerg Saenger,Erich Stoelben,Corinna Ludwig,Walburga Engel-Riedel,Egbert F. Smit,Danille A. M. Heideman,Peter J.F. Snijders,Lucia Nogova,Martin L. Sos,Christian Mattonet,Karin Toepelt,Matthias Scheffler,Eray Goekkurt,Eray Goekkurt,Rainer Kappes,Stefan Krueger,Kato Kambartel,Dirk Behringer,Wolfgang Schulte,Wolfgang Galetke,Winfried Randerath,Matthias Heldwein,Andreas Schlesinger,Monika Serke,Khosro Hekmat,Konrad Frank,Roland Schnell,Marcel Reiser,Ali-Nuri Huenerlituerkoglu,Stephan Schmitz,Lisa Meffert,Yon-Dschun Ko,Markus Litt-Lampe,Ulrich Gerigk,Rainer Fricke,Benjamin Besse,Christian Brambilla,Sylvie Lantuejoul,Philippe Lorimier,Denis Moro-Sibilot,Federico Cappuzzo,C. Ligorio,Stefania Damiani,John K. Field,Russell Hyde,Pierre Validire,Philippe Girard,Lucia Anna Muscarella,Vito Michele Fazio,Michael Hallek,Jean-Charles Soria,Viktor Achter,Ulrich Lang +118 more
TL;DR: Support is provided for broad implementation of genome-based diagnosis of lung cancer by demonstrating the correlation between lung tumor subtype and its predominant mutations, and the benefit of genetic testing and targeted therapy in these patients.
Journal ArticleDOI
Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study.
Max Augustin,Philipp Schommers,Melanie Stecher,Felix Dewald,Lutz Gieselmann,Henning Gruell,Carola Horn,Kanika Vanshylla,Veronica Di Cristanziano,Luise Osebold,Maria Roventa,Toqeer Riaz,Nikolai Tschernoster,Janine Altmueller,Leonard Rose,Susanne Salomon,Vanessa Priesner,Jan Christoffer Luers,Christian Albus,Stephan Rosenkranz,Birgit S. Gathof,Gerd Fätkenheuer,Michael Hallek,Florian Klein,Isabelle Suárez,Clara Lehmann +25 more
TL;DR: The on-going presence of either shortness of breath, anosmia, ageusia or fatigue as long-lasting symptoms even in non-hospitalised patients was observed at four and seven months post-infection and summarised as post-COVID syndrome (PCS).
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
Florence Demenais,Patricia Margaritte-Jeannin,Kathleen C. Barnes,William O.C.M. Cookson,Janine Altmueller,Wei Ang,R. Graham Barr,Terri H. Beaty,Allan B. Becker,John Beilby,Hans Bisgaard,Unnur S. Bjornsdottir,Eugene R. Bleecker,Klaus Bønnelykke,Dorret I. Boomsma,Emmanuelle Bouzigon,Christopher E. Brightling,Myriam Brossard,Guy Brusselle,Esteban G. Burchard,Kristin M. Burkart,Andrew Bush,Moira Chan-Yeung,Kian Fan Chung,Alexessander Couto Alves,John A. Curtin,Adnan Custovic,Denise Daley,Johan C. de Jongste,Blanca E. Del-Rio-Navarro,Kathleen M. Donohue,Liesbeth Duijts,Celeste Eng,Johan G. Eriksson,Martin Farrall,Yuliya Fedorova,Bjarke Feenstra,Manuel A. R. Ferreira,Maxim B. Freidin,Zofia K. Z. Gajdos,Jim Gauderman,Ulrike Gehring,Frank Geller,Jon Genuneit,Sina A. Gharib,Frank D. Gilliland,Raquel Granell,Penelope E. Graves,Daniel F. Gudbjartsson,Tari Haahtela,Susan R. Heckbert,Dick Heederik,Joachim Heinrich,Markku Heliövaara,John Henderson,Blanca E. Himes,Hiroshi Hirose,Joel N. Hirschhorn,Albert Hofman,Patrick G. Holt,Jouke J. Hottenga,Thomas J. Hudson,Jennie Hui,Medea Imboden,Vladimir P. Ivanov,Vincent W. V. Jaddoe,Alan James,Christer Janson,Marjo-Riitta Järvelin,Deborah Jarvis,Graham Jones,Ingileif Jonsdottir,Pekka Jousilahti,Michael Kabesch,Mika Kähönen,David B. Kantor,A. S. Karunas,Elza Khusnutdinova,Gerard H. Koppelman,Anita L. Kozyrskyj,Eskil Kreiner,Michiaki Kubo,Rajesh Kumar,Ashok Kumar,Mikko Kuokkanen,Lies Lahousse,Tarja Laitinen,Catherine Laprise,Mark Lathrop,Susanne Lau,Young-Ae Lee,Terho Lehtimäki,Sébastien Letort,Albert M. Levin,Guo Li,Liming Liang,Laura R. Loehr,Stephanie J. London,Daan W. Loth,Ani Manichaikul,Ingo Marenholz,Fernando J. Martinez,Melanie C. Matheson,Rasika A. Mathias,Kenji Matsumoto,Hamdi Mbarek,Wendy L. McArdle,Mads Melbye,Erik Melén,Deborah A. Meyers,Sven Michel,Hamida Mohamdi,Arthur W. Musk,Rachel A. Myers,Maartje A.E. Nieuwenhuis,Emiko Noguchi,George T. O'Connor,Ludmila M. Ogorodova,Cameron D. Palmer,Aarno Palotie,Julie E. Park,Craig E. Pennell,Göran Pershagen,Alexey Polonikov,Dirkje S. Postma,Nicole Probst-Hensch,V. P. Puzyrev,Benjamin A. Raby,Olli T. Raitakari,Adaikalavan Ramasamy,Stephen S. Rich,Colin F. Robertson,Isabelle Romieu,Muhammad T. Salam,Veikko Salomaa,Vivi Schlünssen,Robert A. Scott,P. A. Selivanova,Torben Sigsgaard,Angela Simpson,Valérie Siroux,Lewis J. Smith,Maria Solodilova,Marie Standl,Kari Stefansson,David P. Strachan,Bruno H. Stricker,Atsushi Takahashi,Philip J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Carla M. T. Tiesler,Dara G. Torgerson,Tatsuhiko Tsunoda,André G. Uitterlinden,Ralf J. P. van der Valk,Amaury Vaysse,Sailaja Vedantam,Andrea von Berg,Erika von Mutius,Judith M. Vonk,Johannes Waage,Nicholas J. Wareham,Scott T. Weiss,Wendy B. White,Magnus Wickman,Elisabeth Widen,Gonneke Willemsen,L. Keoki Williams,Inge M. Wouters,James J. Yang,Jing Hua Zhao,Miriam F. Moffatt,Carole Ober,Dan L. Nicolae +174 more
Journal ArticleDOI
NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly
Metodi D. Metodiev,Henrik Spåhr,Paola Loguercio Polosa,Caroline Meharg,Christian Becker,Janine Altmueller,Bianca Habermann,Nils-Goeran Larsson,Benedetta Ruzzenente +8 more
TL;DR: It is demonstrated that the m5C methyltransferase NSUN4, which forms a complex with MTERF4, is essential in mitochondrial ribosomal biogenesis as mitochondrial translation is abolished in conditional Nsun4 mouse knockouts.
Journal ArticleDOI
A sequence variant on 17q21 is associated with age at onset and severity of asthma
Eva Halapi,Daniel F. Gudbjartsson,Gudrun M. Jonsdottir,Unnur S. Bjornsdottir,Unnur S. Bjornsdottir,Gudmar Thorleifsson,Hafdis T. Helgadottir,Carolyn Williams,Gerard H. Koppelman,Andrea Heinzmann,H. Marike Boezen,Aslaug Jonasdottir,Thorarinn Blondal,Sigurjon A. Gudjonsson,Adalbjorg Jonasdottir,Theodora Thorlacius,Amanda P. Henry,Janine Altmueller,Marcus Krueger,Hyoung Doo Shin,Soo-Taek Uh,Hyun Sub Cheong,Brynja Jonsdottir,Bjorn R. Ludviksson,Dora Ludviksdottir,David Gislason,Choon-Sik Park,Klaus A. Deichmann,Philip J. Thompson,Matthias Wjst,Ian P. Hall,Dirkje S. Postma,Thorarinn Gislason,Augustine Kong,Ingileif Jonsdottir,Ingileif Jonsdottir,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson +39 more
TL;DR: The contribution of rs7216389-T to the development of asthma is unlikely to operate only through an impact on the expression of ORMDL3 or GSDMB genes, as other sequence variants showing a weaker association with asthma compared with that of rs 7216389 were more strongly associated with the expression with both genes.