Richard K. Wilson

TL;DR: The genome sequence of the free-living nematode Caenorhabditis elegans is nearly complete, with resolution of the final difficult regions expected over the next few months, and will represent the first genome of a multicellular organism to be sequenced to completion.

TL;DR: In this article, the authors used a mouse model of APL, whereby PML-RARA expressed in myeloid cells leads to a myeloproliferative disease that ultimately evolves into APL.

TL;DR: It is discovered that alveolar RMS occurs further along the developmental program than embryonal RMS, and comprehensive preclinical testing revealed that targeting the WEE1 kinase in the G2/M pathway is the most effective approach in vivo for high-risk RMS.

TL;DR: It is reported that 5 of 15 patients with genetic clearance of their founding AML clone after induction chemotherapy had a concomitant expansion of a hematopoietic population unrelated to the initial AML, suggesting that nonleukemic hematopolietic stem and progenitor cells, harboring specific aging-acquired mutations, may have a competitive fitness advantage after inductionotherapy, expand, and persist long after the completion of chemotherapy.

TL;DR: Nematode.net currently provides NemaGene EST cluster consensus sequence, enhanced online BLAST search tools, functional classifications of cluster sequences and comprehensive information concerning the ongoing generation of nematode genome data.