R
Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Integrated analysis of germline and somatic variants in ovarian cancer
Krishna L. Kanchi,Kimberly J. Johnson,Kimberly J. Johnson,Charles Lu,Michael D. McLellan,Mark D.M. Leiserson,Michael C. Wendl,Qunyuan Zhang,Daniel C. Koboldt,Mingchao Xie,Cyriac Kandoth,Joshua F. McMichael,Matthew A. Wyczalkowski,David E. Larson,Heather Schmidt,Christopher A. Miller,Robert S. Fulton,Paul T. Spellman,Elaine R. Mardis,Todd E. Druley,Timothy A. Graubert,Paul J. Goodfellow,Benjamin J. Raphael,Richard K. Wilson,Li Ding +24 more
TL;DR: Germline-somatic interaction analysis combined with extensive bioinformatics annotation identifies 237 candidate functional germline truncation and missense variants, including 2 pathogenic BRCA1 and 1 TP53 deleterious variants.
Journal ArticleDOI
The genome of the platyfish, Xiphophorus maculatus , provides insights into evolutionary adaptation and several complex traits
Manfred Schartl,Ronald B. Walter,Yingjia Shen,Tzintzuni Garcia,Julian M. Catchen,Angel Amores,Ingo Braasch,Ingo Braasch,Domitille Chalopin,Jean-Nicolas Volff,Klaus-Peter Lesch,Angelo Bisazza,Patrick Minx,LaDeana W. Hillier,Richard K. Wilson,Susan I. Fuerstenberg,Jeffrey L. Boore,Steve Searle,John H. Postlethwait,Wesley C. Warren +19 more
TL;DR: It is found that genes implicated in cognition show an unexpectedly high rate of duplicate gene retention after the teleost genome duplication event, suggesting a hypothesis for the evolution of the behavioral complexity in fish, which exceeds that found in amphibians and reptiles.
Journal ArticleDOI
Reconstructing complex regions of genomes using long-read sequencing technology
John Huddleston,Swati Ranade,Maika Malig,Francesca Antonacci,Mark Chaisson,Lawrence Hon,Peter H. Sudmant,Tina Graves,Can Alkan,Megan Y. Dennis,Richard K. Wilson,Stephen Turner,Jonas Korlach,Evan E. Eichler +13 more
TL;DR: It is shown that it is possible to resolve regions that are complex in a genome-wide context but simple in isolation for a fraction of the time and cost of traditional methods using long-read single molecule, real-time (SMRT) sequencing and assembly technology from Pacific Biosciences.
Journal ArticleDOI
The DNA sequence of human chromosome 7
LaDeana W. Hillier,Robert S. Fulton,Lucinda Fulton,Tina Graves,Kymberlie H. Pepin,Caryn Wagner-McPherson,Dan Layman,Jason Maas,Sara Jaeger,Rebecca S. Walker,Kristine M. Wylie,Mandeep Sekhon,Michael C. Becker,Michelle O'Laughlin,Mark E. Schaller,Ginger A. Fewell,Kimberly D. Delehaunty,Tracie L. Miner,William E. Nash,Matt Cordes,Hui Du,Hui Sun,Jennifer Edwards,Holland Bradshaw-Cordum,Johar Ali,Stephanie Andrews,Amber Isak,Andrew Vanbrunt,Christine Nguyen,Feiyu Du,Betty Lamar,Laura Courtney,Joelle Kalicki,Philip Ozersky,Lauren Bielicki,Kelsi Scott,Andrea Holmes,Richard Harkins,Anthony R. Harris,Cindy Strong,Shunfang Hou,Chad Tomlinson,Sara Dauphin-Kohlberg,Amy Kozlowicz-Reilly,Shawn Leonard,Theresa Rohlfing,Susan M. Rock,Aye-Mon Tin-Wollam,Amanda Abbott,Patrick Minx,Rachel Maupin,Catrina Strowmatt,Phil Latreille,Nancy Miller,Doug Johnson,Jennifer Murray,Jeffrey Woessner,Michael C. Wendl,Shiaw-Pyng Yang,Brian Schultz,John W. Wallis,John Spieth,Tamberlyn Bieri,Joanne O. Nelson,Nicolas Berkowicz,Patricia Wohldmann,Lisa Cook,Matthew T. Hickenbotham,James M. Eldred,Donald Williams,Joseph A. Bedell,Elaine R. Mardis,Sandra W. Clifton,Stephanie L. Chissoe,Marco A. Marra,Marco A. Marra,Christopher K. Raymond,Eric Haugen,Will Gillett,Yang Zhou,R. James,Karen A. Phelps,Shawn Iadanoto,Kerry L. Bubb,Elizabeth Simms,Ruth Levy,James B. Clendenning,Rajinder Kaul,W. James Kent,Terrence S. Furey,Robert Baertsch,Michael R. Brent,Evan Keibler,Paul Flicek,Peer Bork,Mikita Suyama,Jeffrey A. Bailey,Matthew E. Portnoy,David Torrents,Asif T. Chinwalla,Warren Gish,Sean R. Eddy,John Douglas Mcpherson,John Douglas Mcpherson,Maynard V. Olson,Evan E. Eichler,Eric D. Green,Robert H. Waterston,Robert H. Waterston,Richard K. Wilson +109 more
TL;DR: The euchromatic sequence of chromosome 7, the first metacentric chromosome completed so far, has excellent concordance with previously established physical and genetic maps, and it exhibits an unusual amount of segmentally duplicated sequence.
Journal ArticleDOI
In-depth view of structure, activity, and evolution of rice chromosome 10
Yeisoo Yu,Teri Rambo,Jennifer Currie,Christopher A. Saski,H. R. Kim,Kristi Collura,S. Thompson,J. Simmons,Tae-Jin Yang,G. Nah,Ami Patel,S. Thurmond,David C Henry,R. Oates,Michael Palmer,Gina L Pries,J. Gibson,H. Anderson,M. Paradkar,L. Crane,J. Dale,M. B. Carver,Todd C. Wood,David Frisch,F. Engler,F. Engler,Carol Soderlund,Carol Soderlund,Lance E. Palmer,L. Tetylman,Lidia Nascimento,M. de la Bastide,Lori Spiegel,Doreen Ware,A. O'Shaughnessy,Sujit Dike,Neilay Dedhia,R. Preston,E. Huang,K. Ferraro,K. Kuit,B. Miller,Theresa Zutavern,F. Katzenberger,Stephanie Muller,Vivekanand Balija,Robert A. Martienssen,Lincoln Stein,Patrick Minx,David W. Johnson,Holly Cordum,Elaine R. Mardis,Zhukuan Cheng,Jiming Jiang,Richard K. Wilson,W. R. McCombie,Rod A. Wing,Q. Yuan,Q. Yuan,S. Ouyang,S. Ouyang,Jaime Liu,Jaime Liu,K. M. Jones,K. M. Jones,K. Gansberger,K. Gansberger,K. Moffat,K. Moffat,J. Hill,J. Hill,T. Tsitrin,T. Tsitrin,L. Overton,L. Overton,J. Bera,J. Bera,M. Kim,M. Kim,Sheng Chih Jin,Sheng Chih Jin,L. Tallon,L. Tallon,A. Ciecko,A. Ciecko,G. Pai,G. Pai,S. van Aken,S. van Aken,T. Utterback,T. Utterback,S. Reidmuller,S. Reidmuller,J. Bormann,J. Bormann,T. Feldblyum,T. Feldblyum,J. Hsiao,J. Hsiao,V. Zismann,V. Zismann,S. Blunt,S. Blunt,A. de Vazeilles,A. de Vazeilles,T. Shaffer,T. Shaffer,H. Koo,H. Koo,B. Suh,B. Suh,Q. Yang,Q. Yang,B. Haas,B. Haas,J. Peterson,J. Peterson,Mihaela Pertea,Mihaela Pertea,N. Volfovsky,N. Volfovsky,N. Volfovsky,J. Wortman,J. Wortman,O. White,O. White,Steven L. Salzberg,Steven L. Salzberg,Steven L. Salzberg,Claire M. Fraser,Claire M. Fraser,C. Robin Buell,Joachim Messing,Rentao Song,Galina Fuks,Victor Llaca,S. Kovchak,S. Young,John E. Bowers,Andrew H. Paterson,M. A. Johns,L. Mao,H. Pan,Ralph A. Dean +143 more
TL;DR: In this article, the authors report the sequence of chromosome 10, the smallest of the 12 rice chromosomes (22.4 megabases), which contains 3471 genes and multiple insertions from organellar genomes were detected.