R
Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
The genome of the western clawed frog xenopus tropicalis
Uffe Hellsten,Richard M. Harland,Michael J. Gilchrist,David A. Hendrix,Jerzy Jurka,Vladimir V. Kapitonov,Ivan Ovcharenko,Nicholas H. Putnam,Shengqiang Shu,Leila Taher,Ira L. Blitz,Bruce Blumberg,Darwin S. Dichmann,Inna Dubchak,Enrique Amaya,John C. Detter,Russell B. Fletcher,Daniela S. Gerhard,David Goodstein,Tina Graves,Igor V. Grigoriev,Jane Grimwood,Takeshi Kawashima,Takeshi Kawashima,Erika Lindquist,Susan Lucas,Paul E. Mead,Therese Mitros,Hajime Ogino,Yuko Ohta,Alexander Poliakov,Nicolas Pollet,Jacques Robert,Asaf Salamov,Amy K. Sater,Jeremy Schmutz,Astrid Terry,Peter D. Vize,Wesley C. Warren,Dan E. Wells,Andrea E. Wills,Richard K. Wilson,Lyle B. Zimmerman,Aaron M. Zorn,Robert M. Grainger,Timothy C. Grammer,Mustafa K. Khokha,Paul G. Richardson,Daniel S. Rokhsar,Daniel S. Rokhsar +49 more
TL;DR: The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frogs Xenopus laevis with more tractable genetics.
Journal ArticleDOI
Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
Michael A. Mahowald,Federico E. Rey,Henning Seedorf,Peter J. Turnbaugh,Robert S. Fulton,Aye Wollam,Neha Shah,Chunyan Wang,Vincent Magrini,Richard K. Wilson,Brandi L. Cantarel,Brandi L. Cantarel,Pedro M. Coutinho,Bernard Henrissat,Bernard Henrissat,Lara W. Crock,Alison L Russell,Nathan C Verberkmoes,Robert L. Hettich,Jeffrey I. Gordon +19 more
TL;DR: A simplified model of the human gut microbiota illustrates niche specialization and functional redundancy within members of its major bacterial phyla, and the importance of host glycans as a nutrient foundation that ensures ecosystem stability.
Journal ArticleDOI
Landscape of Somatic Retrotransposition in Human Cancers
Eunjung Lee,Eunjung Lee,Rebecca C. Iskow,Lixing Yang,Omer Gokcumen,Psalm Haseley,Psalm Haseley,Lovelace J. Luquette,Jens G. Lohr,Jens G. Lohr,Chris Harris,Li Ding,Richard K. Wilson,David A. Wheeler,Richard A. Gibbs,Raju Kucherlapati,Raju Kucherlapati,Charles Lee,Peter V. Kharchenko,Peter V. Kharchenko,Peter J. Park,Peter J. Park,Peter J. Park +22 more
TL;DR: Analyzing five cancer types occurring among several individuals found that three types of epithelial tumors exhibited high rates of element movement relative to brain and blood cancers, and Whole-genome sequencing provides evidence for somatic insertions in colorectal, prostate, and ovarian cancers.
Journal ArticleDOI
Genome analysis of the platypus reveals unique signatures of evolution
Wesley C. Warren,LaDeana W. Hillier,Jennifer A. Marshall Graves,Ewan Birney,Chris P. Ponting,Frank Grützner,Katherine Belov,Webb Miller,Laura Clarke,Asif T. Chinwalla,Shiaw Pyng Yang,Andreas Heger,Devin P. Locke,Pat Miethke,Paul D. Waters,Frédéric Veyrunes,Frédéric Veyrunes,Lucinda Fulton,Bob Fulton,Tina Graves,John W. Wallis,Xose S. Puente,Carlos López-Otín,Gonzalo R. Ordóñez,Evan E. Eichler,Lin Chen,Ze Cheng,Janine E. Deakin,Amber E. Alsop,Katherine Thompson,Patrick J. Kirby,Anthony T. Papenfuss,Matthew Wakefield,Tsviya Olender,Doron Lancet,Gavin A. Huttley,Arian F.A. Smit,Andrew J Pask,Peter Temple-Smith,Peter Temple-Smith,Mark A. Batzer,Jerilyn A. Walker,Miriam K. Konkel,Robert S. Harris,Camilla M. Whittington,Emily S. W. Wong,Neil J. Gemmell,Emmanuel Buschiazzo,Iris M. Vargas Jentzsch,Angelika Merkel,Juergen Schmitz,Anja Zemann,Gennady Churakov,Jan Ole Kriegs,Juergen Brosius,Elizabeth P. Murchison,Ravi Sachidanandam,Carly Smith,Gregory J. Hannon,Enkhjargal Tsend-Ayush,Daniel McMillan,Rosalind Attenborough,Willem Rens,Malcolm A. Ferguson-Smith,Christophe Lefevre,Christophe Lefevre,Julie A. Sharp,Kevin R. Nicholas,David A. Ray,Michael Kube,Richard Reinhardt,Thomas H. Pringle,James Taylor,Russell C. Jones,Brett Nixon,Jean Louis Dacheux,Hitoshi Niwa,Yoko Sekita,Xiaoqiu Huang,Alexander Stark,Pouya Kheradpour,Manolis Kellis,Paul Flicek,Yuan Chen,Caleb Webber,Ross C. Hardison,Joanne O. Nelson,Kym Hallsworth-Pepin,Kim D. Delehaunty,Chris Markovic,Patrick Minx,Yucheng Feng,Colin Kremitzki,Makedonka Mitreva,Jarret Glasscock,Todd Wylie,Patricia Wohldmann,Prathapan Thiru,Michael N. Nhan,Craig Pohl,Scott M. Smith,Shunfeng Hou,Marilyn B. Renfree,Elaine R. Mardis,Richard K. Wilson +104 more
TL;DR: It is found that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypUS biology.
Journal ArticleDOI
A Catalog of Reference Genomes from the Human Microbiome
Karen E. Nelson,George M. Weinstock,Sarah K. Highlander,Kim C. Worley,Heather Huot Creasy,Jennifer R. Wortman,Douglas B. Rusch,Makedonka Mitreva,Erica Sodergren,Asif T. Chinwalla,Michael Feldgarden,Dirk Gevers,Brian J. Haas,Ramana Madupu,Doyle V. Ward,Bruce W. Birren,Richard A. Gibbs,Barbara A. Methé,Joseph F. Petrosino,Robert L. Strausberg,Granger G. Sutton,Owen White,Richard K. Wilson,Scott Durkin,Michelle G. Giglio,Sharvari Gujja,Clint Howarth,Chinnappa D. Kodira,Nikos C. Kyrpides,Teena Mehta,Donna M. Muzny,Matthew D. Pearson,Kymberlie H. Pepin,Amrita Pati,Xiang Qin,Chandri N. Yandava,Qiandong Zeng,Lan Zhang,Aaron M. Berlin,Lei Chen,Theresa A. Hepburn,Justin Johnson,Jamison McCorrison,Jason R. Miller,Patrick Minx,Chad Nusbaum,Carsten Russ,Sean M. Sykes,Chad Tomlinson,Sarah Young,Wesley C. Warren,Jonathan H. Badger,Jonathan Crabtree,Victor Markowitz,Joshua Orvis,Andrew Cree,Steve Ferriera,Lucinda Fulton,Robert S. Fulton,Marcus Gillis,Lisa Hemphill,Vandita Joshi,Christie Kovar,Manolito Torralba,Kris A. Wetterstrand,Amr Abouellleil,Aye Wollam,Christian J. Buhay,Yan Ding,Shannon Dugan,Michael Fitzgerald,Mike Holder,Jessica B. Hostetler,Sandra W. Clifton,Emma Allen-Vercoe,Ashlee M. Earl,Candace N. Farmer,Konstantinos Liolios,Michael G. Surette,Qiang Xu,Craig Pohl,Katarzyna Wilczek-Boney,Dianhui Zhu +82 more
TL;DR: Results from an initial reference genome sequencing of 178 microbial genomes allow for ~40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used, suggesting that the authors are still far from saturating microbial species genetic data sets.