R
Richard K. Wilson
Researcher at Nationwide Children's Hospital
Publications - 501
Citations - 294778
Richard K. Wilson is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 173, co-authored 463 publications receiving 260000 citations. Previous affiliations of Richard K. Wilson include University of Washington & St. Jude Children's Research Hospital.
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Journal ArticleDOI
Whole-genome analysis informs breast cancer response to aromatase inhibition
Matthew J. Ellis,Li Ding,Dong Shen,Jingqin Luo,Vera J. Suman,John W. Wallis,Brian A. Van Tine,Jeremy Hoog,Reece J. Goiffon,Theodore C. Goldstein,Sam Ng,Li Lin,Robert J. Crowder,Jacqueline E. Snider,Karla V. Ballman,Jason D. Weber,Ken Chen,Daniel C. Koboldt,Cyriac Kandoth,William Schierding,Joshua F. McMichael,Christopher A. Miller,Charles Lu,Chris Harris,Michael D. McLellan,Michael C. Wendl,Katherine DeSchryver,D. Craig Allred,Laura J. Esserman,Gary Unzeitig,Julie A. Margenthaler,Gildy Babiera,P. Kelly Marcom,J. M. Guenther,Marilyn Leitch,Kelly K. Hunt,John A. Olson,Yu Tao,Christopher G. Maher,Lucinda Fulton,Robert S. Fulton,Michelle Harrison,Ben Oberkfell,Feiyu Du,Ryan Demeter,Tammi L. Vickery,Adnan Elhammali,Helen Piwnica-Worms,Helen Piwnica-Worms,Sandra McDonald,Mark A. Watson,David J. Dooling,David M. Ota,Li-Wei Chang,Ron Bose,Timothy J. Ley,David Piwnica-Worms,Joshua M. Stuart,Richard K. Wilson,Elaine R. Mardis +59 more
TL;DR: To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy are studied by massively parallel sequencing and analysis.
Journal ArticleDOI
The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics
Lincoln Stein,Zhirong Bao,Zhirong Bao,Darin Blasiar,Thomas Blumenthal,Michael R. Brent,Nansheng Chen,Asif T. Chinwalla,Laura Clarke,Chris Clee,Avril Coghlan,Alan Coulson,Alan Coulson,Peter D'Eustachio,Peter D'Eustachio,David H. A. Fitch,Lucinda Fulton,Robert E Fulton,Sam Griffiths-Jones,Todd W. Harris,LaDeana W. Hillier,LaDeana W. Hillier,Ravi Kamath,Patricia E. Kuwabara,Elaine R. Mardis,Marco A. Marra,Marco A. Marra,Tracie L. Miner,Patrick Minx,James C. Mullikin,James C. Mullikin,Robert W. Plumb,Jane Rogers,Jacqueline E. Schein,Jacqueline E. Schein,Marc Sohrmann,John Spieth,Jason E. Stajich,Chaochun Wei,David Willey,Richard K. Wilson,Richard Durbin,Robert H. Waterston,Robert H. Waterston +43 more
TL;DR: Comparisons of the two genomes exhibit extensive colinearity, and the rate of divergence appears to be higher in the chromosomal arms than in the centers, which will help to understand the evolutionary forces that mold nematode genomes.
Journal ArticleDOI
Germline Mutations in Predisposition Genes in Pediatric Cancer
Jinghui Zhang,Michael Walsh,Gang Wu,Michael N. Edmonson,Tanja A. Gruber,John Easton,Dale J. Hedges,Xiaotu Ma,Xin Zhou,Donald Yergeau,Mark R. Wilkinson,Bhavin Vadodaria,Xiang Chen,Rose B. McGee,Stacy Hines-Dowell,Regina Nuccio,Emily Quinn,Sheila A. Shurtleff,Michael Rusch,Aman Patel,Jared Becksfort,Shuoguo Wang,Meaghann S. Weaver,Li Ding,Elaine R. Mardis,Richard K. Wilson,Amar Gajjar,David W. Ellison,Alberto S. Pappo,Ching-Hon Pui,Kim E. Nichols,James R. Downing +31 more
TL;DR: Germline mutations in cancer-predisposing genes were identified in 8.5% of the children and adolescents with cancer, and family history did not predict the presence of an underlying predisposition syndrome in most patients.
Journal ArticleDOI
A physical map of the human genome.
John Douglas Mcpherson,Marco A. Marra,Marco A. Marra,LaDeana W. Hillier,Robert H. Waterston,Asif T. Chinwalla,John W. Wallis,Mandeep Sekhon,Kristine M. Wylie,Elaine R. Mardis,Richard K. Wilson,Robert S. Fulton,Tamara A. Kucaba,Caryn Wagner-McPherson,William B. Barbazuk,Simon G. Gregory,Sean Humphray,Lisa French,R Evans,Graeme Bethel,Adam Whittaker,Jane L. Holden,Owen T. McCann,Andrew Dunham,Carol Soderlund,Carol Scott,David R. Bentley,Gregory D. Schuler,Hsiu Chuan Chen,Wonhee Jang,Eric D. Green,Jacquelyn R. Idol,Valerie Maduro,Kate Montgomery,Eunice Lee,Ashley Miller,Suzanne Emerling,Raju Kucherlapati,Richard A. Gibbs,Steve Scherer,J. Harley Gorrell,Erica Sodergren,Kerstin P. Clerc-Blankenburg,Paul E. Tabor,S. Naylor,Dawn Garcia,J. de Jong,J. de Jong,J. de Jong,Joseph J. Catanese,Joseph J. Catanese,Joseph J. Catanese,Norma J. Nowak,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Kazutoyo Osoegawa,Shizhen Qin,Lee Rowen,Anuradha Madan,Monica Dors,Leroy Hood,Barbara J. Trask,Cynthia Friedman,Hillary Massa,Vivian G. Cheung,Ilan R. Kirsch,Thomas Reid,Raluca Yonescu,Jean Weissenbach,Thomas Brüls,Roland Heilig,Elbert Branscomb,Anne S. Olsen,Norman A. Doggett,Jan Fang Cheng,Trevor Hawkins,Richard M. Myers,Jin Shang,Lucía Ramírez,Jeremy Schmutz,Olivia Velasquez,Kami Dixon,Nancy E. Stone,David R. Cox,David Haussler,W. James Kent,Terrence S. Furey,Sanja Rogic,Scot Kennedy,Steven J.M. Jones,André Rosenthal,Gaiping Wen,Markus Schilhabel,Gernot Gloeckner,Gerald Nyakatura,Reiner Siebert,Brigitte Schlegelberger,Julie R. Korenberg,Xiao Ning Chen,Asao Fujiyama,Masahira Hattori,Atsushi Toyoda,Tetsushi Yada,Hong Seok Park,Yoshiyuki Sakaki,Nobuyoshi Shimizu,Shuichi Asakawa,Kazuhiko Kawasaki,Takashi Sasaki,Ai Shintani,Atsushi Shimizu,Kazunori Shibuya,Jun Kudoh,Shinsei Minoshima,Juliane Ramser,Peter Seranski,Céline Hoff,Annemarie Poustka,Richard Reinhardt,Hans Lehrach +119 more
TL;DR: The construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions are reported.
Journal ArticleDOI
Comparative genomics reveals insights into avian genome evolution and adaptation.
Guojie Zhang,Guojie Zhang,Cai Li,Qiye Li,Bo Li,Denis M. Larkin,Chul Hee Lee,Jay F. Storz,Agostinho Antunes,Matthew J. Greenwold,Robert W. Meredith,Anders Ödeen,Jie Cui,Qi Zhou,Luohao Xu,Hailin Pan,Zongji Wang,Lijun Jin,Pei Zhang,Haofu Hu,Wei Yang,Jiang Hu,Jin Xiao,Zhikai Yang,Yang Liu,Qiaolin Xie,Hao Yu,Jinmin Lian,Ping Wen,Fang Zhang,Hui Li,Yongli Zeng,Zijun Xiong,Shiping Liu,Long Zhou,Zhiyong Huang,Na An,Jie Wang,Qiumei Zheng,Yingqi Xiong,Guangbiao Wang,Bo Wang,Jingjing Wang,Yu Fan,Rute R. da Fonseca,Alonzo Alfaro-Núñez,Mikkel Schubert,Ludovic Orlando,Tobias Mourier,Jason T. Howard,Ganeshkumar Ganapathy,Andreas R. Pfenning,Osceola Whitney,Miriam V. Rivas,Erina Hara,Julia Smith,Marta Farré,Jitendra Narayan,Gancho T. Slavov,Michael N Romanov,Rui Borges,João Paulo Machado,Imran Khan,Mark S. Springer,John Gatesy,Federico G. Hoffmann,Juan C. Opazo,Olle Håstad,Roger H. Sawyer,Heebal Kim,Kyu-Won Kim,Hyeon Jeong Kim,Seoae Cho,Ning Li,Yinhua Huang,Michael William Bruford,Xiangjiang Zhan,Andrew Dixon,Mads F. Bertelsen,Elizabeth P. Derryberry,Wesley C. Warren,Richard K. Wilson,Shengbin Li,David A. Ray,Richard E. Green,Stephen J. O'Brien,Darren K. Griffin,Warren E. Johnson,David Haussler,Oliver A. Ryder,Eske Willerslev,Gary R. Graves,Per Alström,Jon Fjeldså,David P. Mindell,Scott V. Edwards,Edward L. Braun,Carsten Rahbek,David W. Burt,Peter Houde,Yong Zhang,Huanming Yang,Jian Wang,Erich D. Jarvis,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Jun Wang +106 more
TL;DR: This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.