T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
No Association Between Risk of Anterior Cruciate Ligament Rupture and Selected Candidate Collagen Gene Variants in Female Elite Athletes From High-Risk Team Sports:
Einar Andreas Sivertsen,Kari Bente Foss Haug,Eirik Kristianslund,Anne-Marie Siebke Trøseid,Jari Parkkari,Terho Lehtimäki,Nina Mononen,Kati Pasanen,Kati Pasanen,Roald Bahr +9 more
TL;DR: The study does not support a role of the 6 selected SNVs in genes encoding for collagen proteins as risk factors for ACL injury, and genetic profiling to identify athletes at high risk for ACL rupture is not yet feasible.
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Upstream Transcription Factor 1 (USF1) Polymorphisms Associate with Alzheimer's Disease-related Neuropathological Lesions: Tampere Autopsy Study
Karita Isotalo,Eloise Helena Kok,Teemu M. Luoto,Satu Haikonen,Hannu Haapasalo,Terho Lehtimäki,Pekka J. Karhunen +6 more
TL;DR: USF1 has an independent but gender‐ and age‐associated effect on AD‐related brain lesion development, and younger USF1 CCGCAC carriers were more likely to have non‐neuritic and diffuse SP and had lower NFT prevalence among 65+ year‐olds.
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Angiotensin-converting enzyme gene polymorphism is associated with coronary heart disease in non—insulin-dependent diabetic patients evaluated for 9 years
Xiao-Hong Huang,Vappu Rantalaiho,Ole Wirta,Amos Pasternack,Timo Koivula,Timo P. Hiltunen,Tapio Nikkari,Terho Lehtimäki +7 more
TL;DR: The hypothesis that the ACE I/D polymorphism is an important and independent risk factor for CHD in patients with non-insulin-dependent diabetes mellitus (NIDs) is supported.
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Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results.
TL;DR: The suppression of expression of genes associated with T-cell differentiation and antigen-specific T- cell activation detected in this study may contribute to the beneficial effect of MP in relapses of MS.
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High serum n6 fatty acid proportion is associated with lowered LDL oxidation and inflammation: The Cardiovascular Risk in Young Finns Study
Jari Kaikkonen,Petri Kresanov,Markku Ahotupa,Antti Jula,Vera Mikkilä,Jorma Viikari,Mika Kähönen,Terho Lehtimäki,Olli T. Raitakari +8 more
TL;DR: Findings at the population level suggest that PUFAs are negatively and SFAs and MUFAs positively related with LDL oxidation and inflammation; these conclusions are in line with previous observations linking PUF as, particularly n6PUFAs, with lower CVD risk, andSFAs with increased risk.