T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Prognostic implications of intraventricular conduction delays in a general population: The Health 2000 Survey
Petri Haataja,Ismo Anttila,Kjell Nikus,Markku Eskola,Heini Huhtala,Tuomo Nieminen,Antti Jula,Veikko Salomaa,Antti Reunanen,Markku S. Nieminen,Terho Lehtimäki,Samuel Sclarovsky,Mika Kähönen +12 more
TL;DR: In this paper, the prognostic impact of eight different intraventricular conduction delays (IVCD) in the standard electrocardiogram (ECG) in a community cohort was examined.
Journal ArticleDOI
Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype.
Terho Lehtimäki,Prasun Dastidar,Hannu Jokela,Timo Koivula,Saara Lehtinen,Christian Ehnholm,Reijo Punnonen +6 more
TL;DR: The effects of HRT on atherosclerosis progression in subjects with no apo epsilon4-allele seems to be especially beneficial, compared with controls with same phenotype status but without HRT.
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Louise V. Wain,Ahmad Vaez,Rick Jansen,Roby Joehanes,Peter J. van der Most,A. Mesut Erzurumluoglu,Paul F. O'Reilly,Claudia P. Cabrera,Helen R. Warren,Lynda M. Rose,Germaine C. Verwoert,Jouke-Jan Hottenga,Rona J. Strawbridge,Tõnu Esko,Dan E. Arking,Shih-Jen Hwang,Xiuqing Guo,Zoltán Kutalik,Stella Trompet,Nick Shrine,Alexander Teumer,Janina S. Ried,Joshua C. Bis,Albert V. Smith,Najaf Amin,Ilja M. Nolte,Leo-Pekka Lyytikäinen,Anubha Mahajan,Nicholas J. Wareham,Edith Hofer,Peter K. Joshi,Kati Kristiansson,Michela Traglia,Aki S. Havulinna,Anuj Goel,Mike A. Nalls,Siim Sõber,Dragana Vuckovic,Jian'an Luan,Fabiola Del Greco M,Kristin L. Ayers,Jaume Marrugat,Daniela Ruggiero,Lorna M. Lopez,Teemu J. Niiranen,Stefan Enroth,Anne U. Jackson,Christopher P. Nelson,Jennifer E. Huffman,Weihua Zhang,Jonathan Marten,Ilaria Gandin,Sarah E. Harris,Tatijana Zemunik,Yingchang Lu,Evangelos Evangelou,Nabi Shah,Martin H. de Borst,Massimo Mangino,Bram P. Prins,Archie Campbell,Ruifang Li-Gao,Ganesh Chauhan,Christopher Oldmeadow,Gonçalo R. Abecasis,Maryam Abedi,Caterina Barbieri,Michael R. Barnes,Chiara Batini,John Beilby,Tineka Blake,Michael Boehnke,Erwin P. Bottinger,Peter S. Braund,Morris Brown,Marco Brumat,Harry Campbell,John C. Chambers,Massimiliano Cocca,Francis S. Collins,John M. C. Connell,Heather J. Cordell,Jeffrey Damman,Gail Davies,Eco J. C. de Geus,Renée de Mutsert,Joris Deelen,Yusuf Demirkale,Alex S. F. Doney,Marcus Dörr,Martin Farrall,Teresa Ferreira,Mattias Frånberg,He Gao,Vilmantas Giedraitis,Christian Gieger,Franco Giulianini,Alan J. Gow,Anders Hamsten,Tamara B. Harris,Albert Hofman,Elizabeth G. Holliday,Jennie Hui,Marjo-Riitta Järvelin,Åsa Johansson,Andrew D. Johnson,Pekka Jousilahti,Antti Jula,Mika Kähönen,Sekar Kathiresan,Kay-Tee Khaw,Ivana Kolcic,Seppo Koskinen,Claudia Langenberg,Marty Larson,Lenore J. Launer,Benjamin Lehne,David C. Liewald,Li Lin,Lars Lind,François Mach,Chrysovalanto Mamasoula,Cristina Menni,Borbala Mifsud,Yuri Milaneschi,Anna Morgan,Andrew D. Morris,Alanna C. Morrison,Peter J. Munson,Priyanka Nandakumar,Quang Tri Nguyen,Teresa Nutile,Albertine J. Oldehinkel,Ben A. Oostra,Elin Org,Sandosh Padmanabhan,Aarno Palotie,Guillaume Paré,Alison Pattie,Brenda W.J.H. Penninx,Neil Poulter,Peter P. Pramstaller,Olli T. Raitakari,Meixia Ren,Kenneth Rice,Paul M. Ridker,Harriëtte Riese,Samuli Ripatti,Antonietta Robino,Jerome I. Rotter,Igor Rudan,Yasaman Saba,Aude Saint Pierre,Cinzia Sala,Antti-Pekka Sarin,Reinhold Schmidt,Rodney J. Scott,Marc A. Seelen,Denis C. Shields,David S. Siscovick,Rossella Sorice,Alice Stanton,David J. Stott,Johan Sundström,Morris A. Swertz,Kent D. Taylor,Simon Thom,Ioanna Tzoulaki,Christophe Tzourio,André G. Uitterlinden,Uwe Völker,Peter Vollenweider,Sarah H. Wild,Gonneke Willemsen,Alan F. Wright,Jie Yao,Sébastien Thériault,David Conen,John Attia,Peter S. Sever,Stéphanie Debette,Dennis O. Mook-Kanamori,Eleftheria Zeggini,Tim D. Spector,Pim van der Harst,Colin N. A. Palmer,Anne-Claire Vergnaud,Ruth J. F. Loos,Ozren Polasek,John M. Starr,Giorgia Girotto,Caroline Hayward,Jaspal S. Kooner,C M Lindgren,Veronique Vitart,Nilesh J. Samani,Jaakko Tuomilehto,Ulf Gyllensten,Paul Knekt,Ian J. Deary,Marina Ciullo,Roberto Elosua,Bernard Keavney,Andrew A. Hicks,Robert A. Scott,Paolo Gasparini,Maris Laan,Yongmei Liu,Hugh Watkins,Catharina A. Hartman,Veikko Salomaa,Daniela Toniolo,Markus Perola,James F. Wilson,Helena Schmidt,Jing Hua Zhao,Terho Lehtimäki,Cornelia M. van Duijn,Vilmundur Gudnason,Bruce M. Psaty,Annette Peters,Rainer Rettig,Alan James,J. Wouter Jukema,David P. Strachan,Walter Palmas,Andres Metspalu,Erik Ingelsson,Dorret I. Boomsma,Oscar H. Franco,Murielle Bochud,Christopher Newton-Cheh,Patricia B. Munroe,Paul Elliott,Daniel I. Chasman,Aravinda Chakravarti,Joanne Knight,Andrew P. Morris,Daniel Levy,Martin D. Tobin,Harold Snieder,Mark J. Caulfield,Georg Ehret,T. Y. Alistair,J. P. Betholdson,Limin Xiao +245 more
Posted ContentDOI
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction
Ioanna Ntalla,Lu-Chen Weng,Lu-Chen Weng,James H. Cartwright,Amelia W. Hall,Amelia W. Hall,Gardar Sveinbjornsson,Nathan R. Tucker,Nathan R. Tucker,Seung Hoan Choi,Mark Chaffin,Carolina Roselli,Carolina Roselli,Michael R. Barnes,Borbala Mifsud,Borbala Mifsud,Helen R. Warren,Caroline Hayward,Jonathan Marten,James J. Cranley,Maria Pina Concas,Paolo Gasparini,Thibaud Boutin,Ivana Kolcic,Ozren Polasek,Ozren Polasek,Igor Rudan,Nathalia M. Araujo,Maria Fernanda Lima-Costa,Antonio Luiz Pinho Ribeiro,Renan P. Souza,Eduardo Tarazona-Santos,Vilmantas Giedraitis,Erik Ingelsson,Erik Ingelsson,Anubha Mahajan,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,M. Fabiola Del Greco,Luisa Foco,Martin Gögele,Andrew A. Hicks,James P. Cook,Lars Lind,Cecilia M. Lindgren,Cecilia M. Lindgren,Johan Sundström,Christopher P. Nelson,Christopher P. Nelson,Muhammad B. Riaz,Muhammad B. Riaz,Nilesh J. Samani,Nilesh J. Samani,Gianfranco Sinagra,Sheila Ulivi,Mika Kähönen,Pashupati P. Mishra,Nina Mononen,Kjell Nikus,Mark J. Caulfield,Anna F. Dominiczak,Sandosh Padmanabhan,May E. Montasser,Jeffrey R. O'Connell,Kathleen A. Ryan,Alan R. Shuldiner,Stefanie Aeschbacher,David Conen,David Conen,Lorenz Risch,Sébastien Thériault,Sébastien Thériault,Nina Hutri-Kähönen,Terho Lehtimäki,Leo-Pekka Lyytikäinen,Olli T. Raitakari,Catriona L. K. Barnes,Harry Campbell,Peter K. Joshi,James F. Wilson,Aaron Isaacs,Jan A. Kors,Cornelia M. van Duijn,Paul L. Huang,Vilmundur Gudnason,Tamara B. Harris,Lenore J. Launer,Albert V. Smith,Erwin P. Bottinger,Ruth J. F. Loos,Girish N. Nadkarni,Michael Preuss,Adolfo Correa,Hao Mei,James G. Wilson,Thomas Meitinger,Martina Müller-Nurasyid,Annette Peters,Melanie Waldenberger,Massimo Mangino,Massimo Mangino,Tim D. Spector,Michiel Rienstra,Yordi J. van de Vegte,Pim van der Harst,Niek Verweij,Stefan Kääb,Katharina Schramm,Moritz F. Sinner,Konstantin Strauch,Michael J. Cutler,Diane Fatkin,Diane Fatkin,Diane Fatkin,Barry London,Morten S. Olesen,Dan M. Roden,M. Benjamin Shoemaker,J. Gustav Smith,Mary L. Biggs,Joshua C. Bis,Jennifer A. Brody,Bruce M. Psaty,Bruce M. Psaty,Kenneth Rice,Nona Sotoodehnia,Alessandro De Grandi,Christian Fuchsberger,Cristian Pattaro,Peter P. Pramstaller,Ian Ford,J. Wouter Jukema,Peter W. Macfarlane,Stella Trompet,Marcus Dörr,Stephan B. Felix,Uwe Völker,Stefan Weiss,Aki S. Havulinna,Aki S. Havulinna,Antti Jula,Katri Sääksjärvi,Veikko Salomaa,Xiuqing Guo,Susan R. Heckbert,Henry J. Lin,Jerome I. Rotter,Kent D. Taylor,Jie Yao,Renée de Mutsert,Arie C. Maan,Dennis O. Mook-Kanamori,Raymond Noordam,Francesco Cucca,Jun Ding,Edward G. Lakatta,Yong Qian,Kirill V. Tarasov,Daniel Levy,Honghuang Lin,Honghuang Lin,Christopher Newton-Cheh,Christopher Newton-Cheh,Kathryn L. Lunetta,Kathryn L. Lunetta,Alison D. Murray,David J. Porteous,Blair H. Smith,Bruno H. Stricker,André G. Uitterlinden,Marten E. van den Berg,Jeffrey Haessler,Rebecca D. Jackson,Charles Kooperberg,Ulrike Peters,Alexander P. Reiner,Alexander P. Reiner,Eric A. Whitsel,Alvaro Alonso,Dan E. Arking,Eric Boerwinkle,Georg Ehret,Elsayed Z. Soliman,Christy L. Avery,Stephanie M. Gogarten,Kathleen F. Kerr,Cathy C. Laurie,Amanda A. Seyerle,Adrienne M. Stilp,Solmaz Assa,M. Abdullah Said,M. Yldau van der Ende,Pier D. Lambiase,Pier D. Lambiase,Michele Orini,Michele Orini,Julia Ramirez,Julia Ramirez,Stefan van Duijvenboden,Stefan van Duijvenboden,David O. Arnar,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Hilma Holm,Patrick Sulem,Gudmar Thorleifsson,Rosa B. Thorolfsdottir,Rosa B. Thorolfsdottir,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Emelia J. Benjamin,Emelia J. Benjamin,Andrew Tinker,Kari Stefansson,Kari Stefansson,Patrick T. Ellinor,Patrick T. Ellinor,Yalda Jamshidi,Steven A. Lubitz,Steven A. Lubitz,Patricia B. Munroe +221 more
TL;DR: It is shown that polygenic predisposition to PR interval duration is an endophenotype for cardiovascular disease risk, including distal conduction disease, AF, atrioventricular pre-excitation, non-ischemic cardiomyopathy, and coronary heart disease.
Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey
Terhi Kettunen,Carita Eklund,Mika Kähönen,Antti Jula,Hannu Päivä,Leo-Pekka Lyytikäinen,Mikko Hurme,Terho Lehtimäki +7 more
TL;DR: CRP gene allelic variation is associated with CRP levels in both sexes and with one CAE parameter (SI) in men in a population-based Finnish cohort of middle-aged subjects.