T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.
Suzanne Vogelezang,Suzanne Vogelezang,Jonathan P. Bradfield,Tarunveer S. Ahluwalia,John A. Curtin,Timo A. Lakka,Niels Grarup,Markus Scholz,Peter J. van der Most,Claire Monnereau,Claire Monnereau,Evie Stergiakouli,Anni Heiskala,Momoko Horikoshi,Iryna O. Fedko,Natalia Vilor-Tejedor,Diana L. Cousminer,Diana L. Cousminer,Marie Standl,Carol A. Wang,Jorma Viikari,Jorma Viikari,Frank Geller,Carmen Iñiguez,Niina Pitkänen,Niina Pitkänen,Alessandra Chesi,Jonas Bacelis,Jonas Bacelis,Loic Yengo,Loic Yengo,Maties Torrent,Ioanna Ntalla,Øyvind Helgeland,Øyvind Helgeland,Saskia Selzam,Judith M. Vonk,Mohammed H Zafarmand,Mohammed H Zafarmand,Barbara Heude,I. S. Farooqi,Akram Alyass,Robin N Beaumont,Christian Theil Have,Peter Rzehak,Jose Ramon Bilbao,Theresia M. Schnurr,Inês Barroso,Inês Barroso,Klaus Bønnelykke,Lawrence J. Beilin,Lisbeth Carstensen,Marie-Aline Charles,Bo L. Chawes,Karine Clément,Ricardo Closa-Monasterolo,Adnan Custovic,Johan G. Eriksson,Johan G. Eriksson,Joaquin Escribano,Maria M. Groen-Blokhuis,Veit Grote,Dariusz Gruszfeld,Hakon Hakonarson,Hakon Hakonarson,Torben Hansen,Andrew T. Hattersley,Mette Hollensted,Jouke-Jan Hottenga,Elina Hyppönen,Elina Hyppönen,Stefan Johansson,Stefan Johansson,Raimo Joro,Mika Kähönen,Ville Karhunen,Wieland Kiess,Bridget A. Knight,Berthold Koletzko,Andreas Kühnapfel,Kathrin Landgraf,Jean-Paul Langhendries,Terho Lehtimäki,Jaakko T. Leinonen,Aihuali Li,Virpi Lindi,Estelle Lowry,Estelle Lowry,Mariona Bustamante,Carolina Medina-Gomez,Carolina Medina-Gomez,Mads Melbye,Mads Melbye,Kim F. Michaelsen,Camilla Schmidt Morgen,Camilla Schmidt Morgen,Trevor A. Mori,Tenna Ruest Haarmark Nielsen,Tenna Ruest Haarmark Nielsen,Harri Niinikoski,Albertine J. Oldehinkel,Katja Pahkala,Katja Pahkala,Kalliope Panoutsopoulou,Oluf Pedersen,Craig E. Pennell,Christine Power,Sijmen A. Reijneveld,Fernando Rivadeneira,Fernando Rivadeneira,Angela Simpson,Peter D. Sly,Peter D. Sly,Jakob Stokholm,Kook K Teo,Elisabeth Thiering,Nicholas J. Timpson,André G. Uitterlinden,André G. Uitterlinden,Catharina E. M. van Beijsterveldt,Barbera D. C. van Schaik,Marc Vaudel,Marc Vaudel,Elvira Verduci,Rebecca K. Vinding,Mandy Vogel,Eleftheria Zeggini,Eleftheria Zeggini,Sylvain Sebert,Sylvain Sebert,Sylvain Sebert,Mads Vendelbo Lind,Christopher D. Brown,Loreto Santa-Marina,Eva Reischl,Christine Frithioff-Bøjsøe,Christine Frithioff-Bøjsøe,David Meyre,Eleanor Wheeler,Eleanor Wheeler,Ken K. Ong,Ellen A. Nohr,Tanja G. M. Vrijkotte,Gerard H. Koppelman,Robert Plomin,Pål R. Njølstad,Pål R. Njølstad,Pål R. Njølstad,George Dedoussis,Philippe Froguel,Philippe Froguel,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Bo Jacobsson,Bo Jacobsson,Bo Jacobsson,Rachel M. Freathy,Rachel M. Freathy,Babette S. Zemel,Babette S. Zemel,Olli T. Raitakari,Olli T. Raitakari,Martine Vrijheid,Bjarke Feenstra,Leo-Pekka Lyytikäinen,Harold Snieder,Holger Kirsten,Patrick G. Holt,Joachim Heinrich,Joachim Heinrich,Elisabeth Widen,Jordi Sunyer,Dorret I. Boomsma,Dorret I. Boomsma,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Antje Körner,George Davey Smith,Jens-Christian Holm,Jens-Christian Holm,Mustafa Atalay,Clare S. Murray,Hans Bisgaard,Mark I. McCarthy,Mark I. McCarthy,Vincent W. V. Jaddoe,Struan F.A. Grant,Janine F. Felix +187 more
TL;DR: The results suggest that the biological processes underlying childhood BMI largely, but not completely, overlap with those underlying adult BMI.
Journal ArticleDOI
Distinct Variants at LIN28B Influence Growth in Height from Birth to Adulthood
Elisabeth Widen,Samuli Ripatti,Samuli Ripatti,Diana L. Cousminer,Ida Surakka,Ida Surakka,Tuuli Lappalainen,Tuuli Lappalainen,Marjo-Riitta Järvelin,Johan G. Eriksson,Olli T. Raitakari,Olli T. Raitakari,Veikko Salomaa,Ulla Sovio,Anna-Liisa Hartikainen,Anneli Pouta,Mark I. McCarthy,Mark I. McCarthy,Clive Osmond,Eero Kajantie,Terho Lehtimäki,Jorma Viikari,Mika Kähönen,Chris Tyler-Smith,Nelson B. Freimer,Nelson B. Freimer,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Leena Peltonen,Aarno Palotie,Aarno Palotie,Aarno Palotie +32 more
TL;DR: Findings imply a critical role for LIN28B in the regulation of human growth, as well as distinctive, complex, and sex-specific height-growth-regulating effects, influencing the entire period of postnatal growth.
Journal ArticleDOI
Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy.
Hannu Päivä,Terho Lehtimäki,Juha Laakso,Inkeri Ruokonen,Vappu Rantalaiho,Ole Wirta,Amos Pasternack,Reijo Laaksonen +7 more
TL;DR: It is concluded that diabetic patients with a normal or slightly increased GFR have lower circulating ADMA concentrations than nondiabetic control subjects and in type 2 diabetic patients high GFR and poor glycemic control were related to low plasmaADMA concentrations.
Journal ArticleDOI
High Intestinal Cholesterol Absorption Is Associated With Cardiovascular Disease and Risk Alleles in ABCG8 and ABO: Evidence From the LURIC and YFS Cohorts and From a Meta-Analysis
Guenther Silbernagel,M. John Chapman,Bernd Genser,Bernd Genser,Marcus E. Kleber,Marcus E. Kleber,Marcus E. Kleber,Guenter Fauler,Hubert Scharnagl,Tanja B. Grammer,Bernhard O. Boehm,Kari-Matti Mäkelä,Mika Kähönen,Rafael Carmena,Ernst Rietzschel,Ernst Rietzschel,Eric Bruckert,John E. Deanfield,Tatu A. Miettinen,Olli T. Raitakari,Olli T. Raitakari,Terho Lehtimäki,Winfried März,Winfried März,Winfried März +24 more
TL;DR: Harm caused by elevated cholesterol absorption rather than by plant sterols may therefore mediate the relationships of ABCG8 and ABO variants with CVD.
Journal ArticleDOI
Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients
Heidi Immonen,Jarna C. Hannukainen,Patricia Iozzo,Minna Soinio,Paulina Salminen,Virva Saunavaara,Ronald Borra,Riitta Parkkola,Andrea Mari,Terho Lehtimäki,Tam Pham,Jukka Laine,Vesa Kärjä,Jussi Pihlajamäki,Lassi Nelimarkka,Pirjo Nuutila +15 more
TL;DR: This study shows that bariatric surgery leads to a significant improvement in hepatic insulin sensitivity: insulin-stimulated hepatic glucose uptake was improved and endogenous glucose production reduced when measured, six-months, after surgery.