T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Metabolic profiling of alcohol consumption in 9778 young adults
Peter Würtz,Sarah Cook,Qin Wang,Qin Wang,Mika Tiainen,Mika Tiainen,Tuulia Tynkkynen,Tuulia Tynkkynen,Antti J. Kangas,Pasi Soininen,Pasi Soininen,Jaana Laitinen,J. Viikari,Mika Kähönen,Terho Lehtimäki,Markus Perola,Markus Perola,Markus Perola,Stefan Blankenberg,Tanja Zeller,Satu Männistö,Veikko Salomaa,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Olli T. Raitakari,Olli T. Raitakari,Mika Ala-Korpela,David A. Leon +27 more
TL;DR: In this article, the associations of usual alcohol consumption with a comprehensive systemic metabolite profile in young adults were assessed for 9778 individuals from three population-based cohorts from Finland (age 24-45 years, 52% women).
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Interaction between NOTCH4 and catechol-O-methyltransferase genotypes in schizophrenia patients with poor response to typical neuroleptics.
TL;DR: The results suggest that an interaction between COMT and NOTCH4 genotypes may predict the treatment response to typical neuroleptics in patients with schizophrenia.
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New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders
Evangelos Evangelou,Evangelos Evangelou,He Gao,Congying Chu,Georgios Ntritsos,Paul Blakeley,Andrew R. Butts,Raha Pazoki,Hideaki Suzuki,Hideaki Suzuki,Fotios Koskeridis,Andrianos M. Yiorkas,Andrianos M. Yiorkas,Ibrahim Karaman,Joshua Elliott,Qiang Luo,Qiang Luo,Stefanie Aeschbacher,Traci M. Bartz,Sebastian E. Baumeister,Sebastian E. Baumeister,Peter S. Braund,Peter S. Braund,Michael R. Brown,Jennifer A. Brody,Toni-Kim Clarke,Niki Dimou,Jessica D. Faul,Georg Homuth,Anne U. Jackson,Katherine A. Kentistou,Peter K. Joshi,Rozenn N. Lemaitre,Penelope A. Lind,Leo-Pekka Lyytikäinen,Massimo Mangino,Massimo Mangino,Yuri Milaneschi,Christopher P. Nelson,Christopher P. Nelson,Ilja M. Nolte,Mia-Maria Perälä,Ozren Polasek,David J. Porteous,Scott M. Ratliff,Jennifer A. Smith,Alena Stančáková,Alexander Teumer,Samuli Tuominen,Sébastien Thériault,Sébastien Thériault,Jagadish Vangipurapu,John Whitfield,Alexis C. Wood,Jie Yao,Bing Yu,Wei Zhao,Dan E. Arking,Juha Auvinen,Chunyu Liu,Minna Männikkö,Lorenz Risch,Jerome I. Rotter,Harold Snieder,Juha Veijola,Alexandra I. F. Blakemore,Alexandra I. F. Blakemore,Michael Boehnke,Harry Campbell,David Conen,Johan G. Eriksson,Johan G. Eriksson,Hans J. Grabe,Hans J. Grabe,Xiuqing Guo,Pim van der Harst,Catharina A. Hartman,Caroline Hayward,Andrew C. Heath,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Mika Kähönen,Sharon L.R. Kardia,Michael Kühne,Johanna Kuusisto,Markku Laakso,Jari Lahti,Terho Lehtimäki,Andrew M. McIntosh,Karen L. Mohlke,Alanna C. Morrison,Nicholas G. Martin,Albertine J. Oldehinkel,Brenda W.J.H. Penninx,Bruce M. Psaty,Bruce M. Psaty,Olli T. Raitakari,Igor Rudan,Nilesh J. Samani,Nilesh J. Samani,Laura J. Scott,Tim D. Spector,Niek Verweij,David R. Weir,James F. Wilson,Daniel Levy,Ioanna Tzoulaki,Jimmy D. Bell,Paul M. Matthews,Adrian Rothenfluh,Sylvane Desrivières,Gunter Schumann,Gunter Schumann,Paul Elliott +114 more
TL;DR: This article conducted a meta-analysis of genome-wide association studies of alcohol consumption from the UK Biobank, the Alcohol Genome Wide Consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology Plus consortia, collecting data from 480,842 people of European descent to decipher the genetic architecture of alcohol intake.
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
Cornelius A. Rietveld,Sarah E. Medland,Jaime Derringer,Jian Yang,Tõnu Esko,Nicolas W. Martin,Harm-Jan Westra,Konstantin Shakhbazov,Abdel Abdellaoui,Arpana Agrawal,Eva Albrecht,Behrooz Z. Alizadeh,Najaf Amin,John Barnard,Sebastian E. Baumeister,P.J. Benke,L.F. Bielak,Jeffrey A. Boatman,Patricia A. Boyle,Gail Davies,C. deLeeuw,Niina Eklund,Daniel S. Evans,Rudolf Ferhmann,Krista Fischer,Christian Gieger,Håkon K. Gjessing,Sara Hägg,Jennifer R. Harris,Caroline Hayward,Christina Holzapfel,Carla A. Ibrahim-Verbaas,Erik Ingelsson,Bo Jacobsson,Peter K. Joshi,A. Juqessur,Marika Kaakinen,Stavroula Kanoni,Juha Karjalainen,Ivana Kolcic,K. Kristiansson,Zoltán Kutalik,Jari Lahti,Sang Hong Lee,Peng Lin,Penelope A. Lind,Yongmei Liu,Kurt Lohman,Marisa Loitfelder,Gearoid M. McMahon,Pedro Marques-Vidal,Osorio Meirelles,Lili Milani,Ronny Myhre,Marja-Liisa Nuotio,Christopher Oldmeadow,K. Petrovic,Wouter J. Peyrot,Ozren Polasek,Lydia Quaye,Eva Reinmaa,John P. Rice,Thais S. Rizzi,H. Schmidt,Reinhold Schmidt,Albert V. Smith,Jennifer A. Smith,Toshiko Tanaka,Antonio Terracciano,M.J.H.M. van deLoos,Veronique Vitart,Henry Völzke,Jürgen Wellmann,Lei Yu,Wei Zhao,Jüri Allik,John Attia,Stefania Bandinelli,François Bastardot,Jonathan P. Beauchamp,David A. Bennett,Klaus Berger,Laura J. Bierut,Dorret I. Boomsma,Ute Bültmann,Harry Campbell,Christopher F. Chabris,Lynn Cherkas,Mina K. Chung,Francesco Cucca,Mariza deAndrade,Philip L. DeJager,J.E. deNeve,Ian J. Deary,George Dedoussis,Panagiotis Deloukas,Maria Dimitriou,G. Eiriksdottir,Martin F. Elderson,Johan G. Eriksson,David M. Evans,Jessica D. Faul,Luigi Ferrucci,Melissa E. Garcia,Henrik Grönberg,Vilmundur Guonason,Per Hall,Jade Harris,Tamara B. Harris,Nicholas D. Hastie,Andrew C. Heath,Dena G. Hernandez,W. Hoffmann,Rolf Holle,Elizabeth G. Holliday,Jouke-Jan Hottenga,William G. Iacono,Thomas Illig,Marjo-Riitta Järvelin,Mika Kähönen,Jaakko Kaprio,Robert M. Kirkpatrick,Matthew Kowgier,Antti Latvala,L. J. Launer,Debbie A Lawlor,Terho Lehtimäki,Jingmei Li,Paul Lichtenstein,Peter Lichtner,D C Liewald,P. A. F. Madden,Patrik K. E. Magnusson,Tomi E. Mäkinen,G. Masala,Matt McGue,Andres Metspalu,Andreas Mielck,Michael B. Miller,Grant W. Montgomery,Sutapa Mukherjee,Dale R. Nyholt,B.A. Oostra,C. N. A. Palmer,Aarno Palotie,B.W.J.H. Penninx,Markus Perola,Patricia A Peyser,Martin Preisig,Katri Räikkönen,Olli T. Raitakari,Anu Realo,S.M. Ring,Samuli Ripatti,F. Rivadeneira Ramirez,Igor Rudan,Aldo Rustichini,Veikko Salomaa,Antti-Pekka Sarin,David Schlessinger,Rodney J. Scott,Harold Snieder,B. St Pourcain,John M. Starr,Jae Hoon Sul,Ida Surakka,Rauli Svento,Alexander Teumer,Henning Tiemeier,F.J.A. vanRooij,D.R. vanWagoner,Erkki Vartiainen,Jorma Viikari,Peter Vollenweider,J. M. Vonk,G. Waeber,David R. Weir,H. E. Wichmann,E. Widen,Gonneke Willemsen,James F. Wilson,Alan F. Wright,Dalton Conley,George Davey-Smith,Lude Franke,Patrick J. F. Groenen,Albert Hofman,Magnus Johannesson,Sharon L.R. Kardia,Robert F. Krueger,David Laibson,Nicholas G. Martin,Michelle N. Meyer,Danielle Posthuma,A.R. Thurik,Nicholas J. Timpson,A.G. Uitterlinden,C.M. vanDuijn,Peter M. Visscher,Daniel J. Benjamin,David Cesarini,Koellinger +201 more
TL;DR: Three genetic loci are found to explain variation associated with educational achievement and provide promising candidate SNPs for follow-up work, and effect size estimates can anchor power analyses in social-science genetics.
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Antibodies against copper-oxidised and malondialdehyde-modified low density lipoproteins in pre-eclamptic pregnancies
TL;DR: The objective is to measure auto‐antibodies against oxidatively modified low density lipoprotein (LDL) in pre‐eclamptic pregnancies using two different techniques.