T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Indoleamine 2,3-dioxygenase activation and depressive symptoms: results from the Young Finns Study.
Marko Elovainio,Mikko Hurme,Markus Jokela,Laura Pulkki-Råback,Mika Kivimäki,Mirka Hintsanen,Taina Hintsa,Terho Lehtimäki,Jorma Viikari,Olli T. Raitakari,Liisa Keltikangas-Järvinen +10 more
TL;DR: Data suggest that IDO activity may be a risk factor for future depression especially in women, and IDO-induced alterations in serotonergic function may offer one biologic explanation to the well-established associations between inflammation and depression.
Journal ArticleDOI
Variability gene effects of DNA polymorphisms at the apo B, apo A I/C III and apo E loci on serum lipids: the Cardiovascular Risk in Young Finns Study.
K.V.K. Porkka,Simo Taimela,Kimmo Kontula,Terho Lehtimäki,Katriina Aalto-Setälä,Hans K. Åkerblom,Jorma Viikari +6 more
TL;DR: Many of the presently known DNA polymorphisms of the coronary heart disease candidate gene loci also influence intraindividual variability of serum lipid or lipoprotein levels, and can be used to further refine the ability to predict the risk of a cardiovascular event.
Journal ArticleDOI
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function
Man Li,Man Li,Yong Li,Olivia Weeks,Vladan Mijatovic,Alexander Teumer,Jennifer E. Huffman,Jennifer E. Huffman,Gerard Tromp,Gerard Tromp,Christian Fuchsberger,Mathias Gorski,Leo Pekka Lyytikäinen,Leo Pekka Lyytikäinen,Teresa Nutile,Sanaz Sedaghat,Rossella Sorice,Adrienne Tin,Qiong Yang,Tarunveer S. Ahluwalia,Dan E. Arking,Nathan A. Bihlmeyer,Carsten A. Böger,Robert J. Carroll,Daniel I. Chasman,Marilyn C. Cornelis,Abbas Dehghan,Jessica D. Faul,Mary F. Feitosa,Giovanni Gambaro,Paolo Gasparini,Franco Giulianini,Iris M. Heid,Jinyan Huang,Jinyan Huang,Medea Imboden,Anne U. Jackson,Janina M. Jeff,Min A. Jhun,Ronit Katz,Annette Kifley,Tuomas O. Kilpeläinen,Ashok Kumar,Markku Laakso,Ruifang Li-Gao,Kurt Lohman,Yingchang Lu,Reedik Mägi,Giovanni Malerba,Evelin Mihailov,Karen L. Mohlke,Dennis O. Mook-Kanamori,Antonietta Robino,Douglas Ruderfer,Erika Salvi,Ursula M. Schick,Christina-Alexandra Schulz,Albert V. Smith,Jennifer A. Smith,Michela Traglia,Laura M. Yerges-Armstrong,Wei Zhao,Mark O. Goodarzi,Aldi T. Kraja,Chunyu Liu,Jennifer Wessel,Eric Boerwinkle,Ingrid B. Borecki,Jette Bork-Jensen,Erwin P. Bottinger,Daniele Braga,Ivan Brandslund,Jennifer A. Brody,Archie Campbell,David J. Carey,Cramer Christensen,Josef Coresh,Errol D. Crook,Gary C. Curhan,D. Cusi,D. Cusi,Ian H. De Boer,Aiko P. J. de Vries,Joshua C. Denny,Olivier Devuyst,Albert W. Dreisbach,Karlhans Endlich,Tõnu Esko,Oscar H. Franco,Tibor Fülöp,Glenn S. Gerhard,Charlotte Glümer,Omri Gottesman,Niels Grarup,Vilmundur Gudnason,Torben Hansen,Tamara B. Harris,Caroline Hayward,Lynne J. Hocking,Albert Hofman,Frank B. Hu,Lise Lotte N. Husemoen,Rebecca D. Jackson,Torben Jørgensen,Marit E. Jørgensen,Mika Kähönen,Sharon L.R. Kardia,Wolfgang König,Charles Kooperberg,Jennifer Kriebel,Lenore J. Launer,Torsten Lauritzen,Terho Lehtimäki,Daniel Levy,Pamela Linksted,Allan Linneberg,Yongmei Liu,Ruth J. F. Loos,Antonio Lupo,Christine Meisinger,Olle Melander,Andres Metspalu,Paul Mitchell,Matthias Nauck,Peter Nürnberg,Marju Orho-Melander,Afshin Parsa,Oluf Pedersen,Annette Peters,Ulrike Peters,Ozren Polasek,David J. Porteous,Nicole Probst-Hensch,Bruce M. Psaty,Lu Qi,Olli T. Raitakari,Alexander P. Reiner,Rainer Rettig,Paul M. Ridker,Fernando Rivadeneira,Jacques E. Rossouw,Frank Schmidt,David S. Siscovick,Nicole Soranzo,Konstantin Strauch,Daniela Toniolo,Stephen T. Turner,André G. Uitterlinden,Sheila Ulivi,Dinesh Velayutham,Uwe Völker,Henry Völzke,Melanie Waldenberger,Jie Jin Wang,David R. Weir,Daniel R. Witte,Helena Kuivaniemi,Caroline S. Fox,Nora Franceschini,Wolfram Goessling,Anna Köttgen,Anna Köttgen,Audrey Y. Chu,Audrey Y. Chu +163 more
TL;DR: A two-stage meta-analysis of associations between genotypes from the Illumina exome array and eGFR on the basis of serum creatinine among participants of European ancestry from the CKDGen Consortium identifies novel genes with potential roles in kidney formation.
Journal ArticleDOI
Model selection for metabolomics: predicting diagnosis of coronary artery disease using automated machine learning.
Alena Orlenko,Daniel Kofink,Leo-Pekka Lyytikäinen,Kjell Nikus,Pashupati P. Mishra,Pekka Kuukasjärvi,Pekka J. Karhunen,Mika Kähönen,Jari Laurikka,Terho Lehtimäki,Folkert W. Asselbergs,Jason H. Moore +11 more
TL;DR: It is demonstrated that the phenotypic profile that distinguishes non-obstructive CAD patients from no CAD patients is associated with higher precision, suggesting a discrepancy in the underlying processes between these phenotypes.
Journal ArticleDOI
The Effect of Weight on Labor Market Outcomes: an Application of Genetic Instrumental Variables
Petri Böckerman,John Cawley,Jutta Viinikainen,Terho Lehtimäki,Suvi P. Rovio,Ilkka Seppälä,Jaakko Pehkonen,Olli T. Raitakari,Olli T. Raitakari +8 more
TL;DR: In this article, the authors used genetic risk score, which reflects the predisposition to higher body mass index across many genetic loci, to estimate IV models of the effect of BMI on labor market outcomes.