T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Evolution of genetic networks for human creativity.
Igor Zwir,Igor Zwir,Coral Del-Val,Mirka Hintsanen,Kevin M. Cloninger,Rocío Romero-Zaliz,Alberto Mesa,Javier Arnedo,Ramiro Salas,G. F. Poblete,G. F. Poblete,Emma Raitoharju,Olli T. Raitakari,Liisa Keltikangas-Järvinen,G. A. de Erausquin,I. Tattersall,Terho Lehtimäki,Claude Robert Cloninger +17 more
TL;DR: The authors found that modern humans have more than 200 unique non-protein coding genes regulating co-expression of many more protein-coding genes in coordinated networks that underlie their capacities for self-awareness, creativity, prosocial behavior, and healthy longevity, which are not found in chimpanzees or Neanderthals.
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Susceptibility of LDL to oxidation is not associated with the presence of coronary heart disease or renal dysfunction in NIDDM patients
Janne S. Leinonen,Vappu Rantalaiho,Tiina Solakivi,Timo Koivula,Ole Wirta,Amos Pasternack,Hannu Alho,Terho Lehtimäki +7 more
TL;DR: Data suggest that diabetes and hyperglycemia per se do not affect the susceptibility of LDL to oxidation, and the presence of CHD or renal dysfunction were not associated with LDL susceptibility to oxidation.
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Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey.
Terhi Kettunen,Carita Eklund,Mika Kähönen,Antti Jula,Hannu Päivä,Leo-Pekka Lyytikäinen,Mikko Hurme,Terho Lehtimäki +7 more
TL;DR: In this paper, the authors assessed whether C-reactive protein (CRP) genotypes or their haplotypes associate with plasma CRP levels or carotid artery intima-media thickness (IMT) or carotorid artery elasticity (CAE) in a Finnish middle-aged study population.
Journal Article
Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study.
Jenni Hällfors,Anu Loukola,Janne Pitkäniemi,Ulla Broms,Satu Männistö,Veikko Salomaa,Markku Heliövaara,Terho Lehtimäki,Olli T. Raitakari,Pamela A. F. Madden,Andrew C. Heath,Grant W. Montgomery,Nicholas G. Martin,Tellervo Korhonen,Jaakko Kaprio +14 more
TL;DR: The results provide further evidence for the nicotine-specific role of rs16969968 (locus 1) and suggest that the effect of rs588765 ( locus 3) may be specific to alcohol use as the effect is seen also in never smokers.
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Presence of apolipoprotein E ϵ4 allele predisposes to early onset of primary Sjögren's syndrome
TL;DR: A clear association prevails between apoE epsilon4 and early onset of pSS, and ApoE polymorphism was not associated with signs of inflammation evaluated by such markers as concentration of plasma CRP, plasma interleukin-6, plasma TNF-alpha, immunoglobulin G and haemoglobin, or leucocyte count or ESR.