T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study.
Niina Pitkänen,Markus Juonala,Tapani Rönnemaa,Matthew A. Sabin,Nina Hutri-Kähönen,Mika Kähönen,Terho Lehtimäki,Jorma Viikari,Olli T. Raitakari +8 more
TL;DR: A multifactorial approach combining genetic and clinical risk factors may be useful in identifying children at high risk for adult IFG and type 2 diabetes.
Journal ArticleDOI
Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study
J. Raiko,Costan G. Magnussen,Mika Kivimäki,Mika Kivimäki,Leena Taittonen,Tomi Laitinen,Mika Kähönen,Nina Hutri-Kähönen,Antti Jula,Britt-Marie Loo,Russell Thomson,Terho Lehtimäki,Jorma Viikari,Olli T. Raitakari,Markus Juonala +14 more
TL;DR: Cardiovascular disease risk scores had equal value in predicting subclinical atherosclerosis measured by IMT and CDist in young adults and SCORE was more accurate in predicting low FMD than Framingham risk score.
Journal ArticleDOI
Higher Maternal Body Mass Index Is Associated with an Increased Risk for Later Type 2 Diabetes in Offspring
Markus Juonala,Paula Jääskeläinen,Matthew A. Sabin,Jorma Viikari,Mika Kähönen,Terho Lehtimäki,Ilkka Seppälä,Nina Hutri-Kähönen,Leena Taittonen,Eero Jokinen,Tomi Laitinen,Costan G. Magnussen,Costan G. Magnussen,Olli T. Raitakari +13 more
TL;DR: Maternal BMI is a useful variable in determining offspring risk of developing type 2 diabetes, in a multivariable analysis adjusted for age, sex, type 1 diabetes genetic risk score, childhood BMI, insulin, lipids, dietary factors, socioeconomic status, and mother's age.
Journal ArticleDOI
The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study.
Meng Fan,Mika Kähönen,Riikka Rontu,Rami Lehtinen,Jari Viik,Mari Niemi,Tuomo Nieminen,Kari Niemelä,Ilkka Pörsti,Tiit Kööbi,Väinö Turjanmaa,Terho Lehtimäki +11 more
TL;DR: The T allele in the C242Tpolymorphism of the p22phox gene had a protective effect against the development of CAD despite the exposure of study subjects to risk factors related to excessive NADPH-dependent superoxide production.
Journal ArticleDOI
Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk.
Olli T. Raitakari,Olli T. Raitakari,Ville-Petteri Mäkinen,Matthew J. McQueen,Jaakko Niemi,Markus Juonala,Matti Jauhiainen,Veikko Salomaa,Minna L. Hannuksela,Markku J. Savolainen,Y. Antero Kesäniemi,Petri T. Kovanen,Jouko Sundvall,Tiina Solakivi,Britt Marie Loo,Jukka Marniemi,Jussi Hernesniemi,Terho Lehtimäki,Mika Kähönen,Markku Peltonen,Jaana Leiviskä,Antti Jula,Sonia S. Anand,Ruby Miller,Salim Yusuf,Jorma Viikari,Mika Ala-Korpela +26 more
TL;DR: Estimated apoB/apoA1-ratio calculated from non-fasting lipids in over 20,000 individuals in the INTERHEART study was better than any of the cholesterol measures for estimation of the myocardial risk.