T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Association of Neuropeptide Y Polymorphism With the Occurrence of Type 1 and Type 2 Alcoholism
Erkki Ilveskoski,Olli A. Kajander,Terho Lehtimäki,Tarja Kunnas,Pekka J. Karhunen,Pekka Heinälä,Matti Virkkunen,Hannu Alho +7 more
TL;DR: It is speculated that the genetic polymorphism producing the proline(7) substitution of NPY might not predispose to alcoholism, but indeed retard the transition to alcoholism.
Journal ArticleDOI
Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults
Mari Sandell,Ulla Hoppu,Vera Mikkilä,Vera Mikkilä,Nina Mononen,Mika Kähönen,Satu Männistö,Tapani Rönnemaa,Tapani Rönnemaa,Jorma S. A. Viikari,Jorma S. A. Viikari,Terho Lehtimäki,Olli T. Raitakari,Olli T. Raitakari +13 more
TL;DR: This study showed that the hTAS2R38 taste receptor gene variation was associated with vegetable and sweet food consumption among adults in a Finnish population.
Journal ArticleDOI
Metabolic syndrome in childhood and increased arterial stiffness in adulthood: the Cardiovascular Risk In Young Finns Study.
Teemu Koivistoinen,Nina Hutri-Kähönen,Markus Juonala,Heikki Aatola,Tiit Kööbi,Terho Lehtimäki,Jorma Viikari,Olli T. Raitakari,Mika Kähönen +8 more
TL;DR: Examination of the associations of two different paediatric metabolic syndrome definitions and recovery from childhood MetS with arterial pulse wave velocity (PWV), an index of arterial stiffness, measured in adulthood found that MetS in childhood predicted increased arterIAL stiffness in adulthood, and recovery in adulthood was associated with decreased arterial PWV.
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Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.
Nina Mononen,Leo-Pekka Lyytikäinen,Ilkka Seppälä,Pashupati P. Mishra,Markus Juonala,Melanie Waldenberger,Norman Klopp,Thomas Illig,Jaana Leiviskä,Britt-Marie Loo,Reijo Laaksonen,Niku Oksala,Mika Kähönen,Nina Hutri-Kähönen,Olli T. Raitakari,Olli T. Raitakari,Terho Lehtimäki,Emma Raitoharju +17 more
TL;DR: There were significant differences in the microRNA profiles associated with glucose, insulin, or HOMA-IR compared to those associated with HbA1c.
Journal ArticleDOI
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.
Salman M. Tajuddin,Ursula M. Schick,John D. Eicher,Nathalie Chami,Ayush Giri,Jennifer A. Brody,W. David Hill,Tim Kacprowski,Jin Li,Leo-Pekka Lyytikäinen,Ani Manichaikul,Evelin Mihailov,Michelle L. O'Donoghue,Nathan Pankratz,Raha Pazoki,Linda M. Polfus,Albert V. Smith,Claudia Schurmann,Caterina Vacchi-Suzzi,Dawn M. Waterworth,Evangelos Evangelou,Evangelos Evangelou,Lisa R. Yanek,Amber A. Burt,Ming-Huei Chen,Frank J. A. van Rooij,James S. Floyd,Andreas Greinacher,Tamara B. Harris,Heather M. Highland,Heather M. Highland,Leslie A. Lange,Yongmei Liu,Reedik Mägi,Mike A. Nalls,Rasika A. Mathias,Deborah A. Nickerson,Kjell Nikus,John M. Starr,Jean-Claude Tardif,Ioanna Tzoulaki,Ioanna Tzoulaki,Digna R. Velez Edwards,Lars Wallentin,Traci M. Bartz,Lewis C. Becker,Joshua C. Denny,Laura M. Raffield,John D. Rioux,Nele Friedrich,Myriam Fornage,He Gao,Joel N. Hirschhorn,Joel N. Hirschhorn,David C. Liewald,Stephen S. Rich,André G. Uitterlinden,Lisa Bastarache,Diane M. Becker,Eric Boerwinkle,Eric Boerwinkle,Simon de Denus,Erwin P. Bottinger,Caroline Hayward,Albert Hofman,Albert Hofman,Georg Homuth,Ethan M. Lange,Lenore J. Launer,Terho Lehtimäki,Yingchang Lu,Andres Metspalu,Christopher J. O'Donnell,Rakale C. Quarells,Melissa A. Richard,Eric S. Torstenson,Kent D. Taylor,Anne-Claire Vergnaud,Alan B. Zonderman,David R. Crosslin,Ian J. Deary,Marcus Dörr,Paul Elliott,Michele K. Evans,Vilmundur Gudnason,Mika Kähönen,Bruce M. Psaty,Bruce M. Psaty,Jerome I. Rotter,Andrew J. Slater,Abbas Dehghan,Harvey D. White,Santhi K. Ganesh,Ruth J. F. Loos,Tõnu Esko,Tõnu Esko,Nauder Faraday,James G. Wilson,Mary Cushman,Andrew D. Johnson,Todd L. Edwards,Neil A. Zakai,Guillaume Lettre,Alexander P. Reiner,Alexander P. Reiner,Paul L. Auer +105 more
TL;DR: An exome array-based meta-analysis of total WBC and subtype counts in a multi-ancestry discovery and replication sample of ∼157,622 individuals suggests a prominent shared genetic architecture with inflammatory and autoimmune diseases.