Terho Lehtimäki

TL;DR: In this article, the authors employed proteomics and in vitro functional assays to identify the unique characteristics of intimal smooth muscle cells (SMC) isolated from human carotid endarterectomy specimens and medial SMC from thoracic aortas and carotids.

TL;DR: The statistical significance of the association of serum total cholesterol and low density lipoprotein (LDL) concentration with apoE phenotype increased from the low SAFA-cholesterol group to the high SA FA-ch cholesterol group, and the middle SAFA -cholesterol groups fell between these two groups.

TL;DR: It is shown that polygenic predisposition to PR interval duration is an endophenotype for cardiovascular disease, including distal conduction disease, AF, and atrioventricular pre-excitation, and these findings advance the understanding of the polygenic basis of cardiac conduction, and the genetic relationship betweenPR interval duration and cardiovascular disease.

TL;DR: It was found that the combination of COMT Met allele and DRD2 T allele predicted more severe depression in those already affected but did not predict the risk of depression when compared to normal population.

TL;DR: In this paper, the authors identified a variant (rs12225230) in APOA1 locus that associated with circulating apoA-I concentrations, with the association showing a dose-response relationship.