Terho Lehtimäki

TL;DR: This work investigated which factors explain the variation in SAA and analysed whether SAA could be associated with preclinical atherosclerosis.

TL;DR: Hippocampal VFC appears to be a form of vascular pathology with a unique predilection for the middle hippocampal artery and corresponding capillary network, which results in patchy neurons loss in moderately affected subjects and in almost total neuronal loss in the area of impaired blood supply in severely affected subjects.

TL;DR: The results suggest that the lack of CCR5 does not protect from multiple sclerosis, but rather it may predispose to the chronic course of the disease.

TL;DR: A meta-analysis of genome-wide association studies of alcohol consumption from the UK Biobank, the Alcohol Genome-Wide Consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology Plus consortia identifies 46 new common loci associated with alcohol consumption and suggests genetic mechanisms that are shared with neuropsychiatric disorders such as schizophrenia.

TL;DR: Reducing childhood infections, especially in socioeconomic disadvantaged children, may reduce the cardiometabolic disease burden in adults, and this findings suggest childhood infection may contribute to social gradients observed in adult cardiometric disease risk factors.