T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal Article
High dose statins and skeletal muscle metabolism in man: A randomized controlled trial.
Rudy Van Coster,Joél Smet,Boel De Paepe,Hannu Päivä,Karin M. Thelen,Kari M. Mattila,Juha Laakso,Terho Lehtimäki,K Von Bergmann,Dieter Lütjohann,Reijo Laaksonen +10 more
Journal ArticleDOI
New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus
Janne S. Leinonen,Terho Lehtimäki,Shinya Toyokuni,Kunihiko Okada,Tomoyuki Tanaka,Hiroshi Hiai,Hirotomo Ochi,Pekka Laippala,Vappu Rantalaiho,Ole Wirta,Amos Pasternack,Hannu Alho +11 more
TL;DR: The increased excretion of urinary 8‐OHdG is seen as indicating an increased systemic level of oxidative DNA damage in NIDDM patients.
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The prevalence of peripheral arterial disease and medial arterial calcification in patients with chronic renal failure: requirements for diagnostics.
TL;DR: Both asymptomatic PAD and MAC are common in patients with CRF and are recommend the use of both ABI and TBI measurements in the evaluation of PAD in patientswith CRF.
Journal ArticleDOI
Genome-wide Association Study in 79,366 European-ancestry Individuals Informs the Genetic Architecture of 25-Hydroxyvitamin D Levels
Xia Jiang,Xia Jiang,Paul F. O'Reilly,Hugues Aschard,Hugues Aschard,Yi-Hsiang Hsu,Yi-Hsiang Hsu,J. Brent Richards,Josée Dupuis,Josée Dupuis,Erik Ingelsson,Erik Ingelsson,David Karasik,Stefan Pilz,Diane J. Berry,Bryan Kestenbaum,Ju-Sheng Zheng,Jian'an Luan,Eleni Sofianopoulou,Elizabeth A. Streeten,Demetrius Albanes,Pamela L. Lutsey,Lu Yao,Weihong Tang,Michael J. Econs,Henri Wallaschofski,Henry Völzke,Ang Zhou,Chris Power,Mark I. McCarthy,Erin D. Michos,Eric Boerwinkle,Stephanie J. Weinstein,Neal D. Freedman,Wen-Yi Huang,Natasja M. van Schoor,Nathalie van der Velde,Nathalie van der Velde,Lisette C. P. G. M. de Groot,Anke W. Enneman,L. Adrienne Cupples,L. Adrienne Cupples,Sarah L. Booth,Ramachandran S. Vasan,Ching-Ti Liu,Yanhua Zhou,Samuli Ripatti,Claes Ohlsson,Liesbeth Vandenput,Mattias Lorentzon,Johan G. Eriksson,M. Kyla Shea,Denise K. Houston,Stephen B. Kritchevsky,Yongmei Liu,Kurt Lohman,Luigi Ferrucci,Munro Peacock,Christian Gieger,Marian Beekman,Eline Slagboom,Joris Deelen,Joris Deelen,Diana van Heemst,Marcus E. Kleber,Winfried März,Winfried März,Winfried März,Ian H. de Boer,Alexis C. Wood,Jerome I. Rotter,Stephen S. Rich,Cassianne Robinson-Cohen,Martin den Heijer,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Alana Cavadino,Alana Cavadino,Peter K. Joshi,James F. Wilson,Caroline Hayward,Lars Lind,Karl Michaëlsson,Stella Trompet,M. Carola Zillikens,André G. Uitterlinden,Fernando Rivadeneira,Linda Broer,Lina Zgaga,Harry Campbell,Evropi Theodoratou,Susan M. Farrington,Maria Timofeeva,Malcolm G. Dunlop,Ana M. Valdes,Ana M. Valdes,Emmi Tikkanen,Terho Lehtimäki,Leo-Pekka Lyytikäinen,Mika Kähönen,Olli T. Raitakari,Vera Mikkilä,M. Arfan Ikram,Naveed Sattar,J. Wouter Jukema,Nicholas J. Wareham,Claudia Langenberg,Nita G. Forouhi,Thomas E. Gundersen,Kay-Tee Khaw,Adam S. Butterworth,John Danesh,John Danesh,Tim D. Spector,Thomas J. Wang,Elina Hyppönen,Elina Hyppönen,Peter Kraft,Douglas P. Kiel,Douglas P. Kiel +119 more
TL;DR: In a genome-wide association study of 79,366 individuals, Jiang et al. replicate four and identify two new genetic loci for serum levels of 25-hydroxyvitamin D and find evidence for a shared genetic basis with autoimmune diseases.
Journal ArticleDOI
Coronary Flow Reserve Is Reduced in Young Men With IDDM
Olli-Pekka Pitkänen,Pirjo Nuutila,Olli T. Raitakari,Tapani Rönnemaa,Pertti J Koskinen,Hidehiro Iida,Terho Lehtimäki,Hanna Laine,Teemu Takala,Jorma Viikari,Juhani Knuuti +10 more
TL;DR: Coronary flow reserve is impaired in young adult males with IDDM and no or minimal microvascular complications and without any evidence of coronary heart disease, which implies early impairment of coronary vascular reactivity in IDDM patients, which may represent an early precursor of future coronary heart diseases or contribute to the pathogenesis of diabetic cardiomyopathy.