T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Elevated plasma fibrinogen caused by inadequate α-linolenic acid intake can be reduced by replacing fat with canola-type rapeseed oil
Tuulikki Seppänen-Laakso,Tuulikki Seppänen-Laakso,Into Laakso,Terho Lehtimäki,Riikka Rontu,Eeva Moilanen,Tiina Solakivi,L. Seppo,H. Vanhanen,K. Kiviranta,Raimo Hiltunen +10 more
TL;DR: The associations and changes in plasma C18 and LC PUFA followed the competitive and metabolic principles of the body, and especially in the case of n-3 PUFA according to the recycling pathway.
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Gene-environment interactions between education and body mass: Evidence from the UK and Finland.
Vikesh Amin,Petri Böckerman,Jutta Viinikainen,Melissa C. Smart,Yanchun Bao,Meena Kumari,Niina Pitkänen,Terho Lehtimäki,Olli T. Raitakari,Jaakko Pehkonen +9 more
TL;DR: The estimates show that education is negatively associated with BMI and overweightness, and genetic risk is positively associated, however, the interactions between education and Genetic risk are small and statistically insignificant.
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Effects of long-term estrogen replacement therapy versus combined hormone replacement therapy on nitric oxide-dependent vasomotor function.
Hannu Jokela,Prasun Dastidar,Riikka Rontu,Anne Salomäki,K. Teisala,Terho Lehtimäki,Reijo Punnonen +6 more
TL;DR: The results suggest that the favorable effects of long-term estrogen treatment on blood flow are at least partly mediated through NO, and the addition of levonorgestrel to the treatment regimen appears to abolish this effect.
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Genome-Wide Meta-Analysis of Sciatica in Finnish Population
Susanna Lemmelä,Svetlana Solovieva,Rahman Shiri,Christian Benner,Markku Heliövaara,Johannes Kettunen,Johannes Kettunen,Johannes Kettunen,Verneri Anttila,Verneri Anttila,Samuli Ripatti,Samuli Ripatti,Markus Perola,Markus Perola,Markus Perola,Ilkka Seppälä,Markus Juonala,Markus Juonala,Mika Kähönen,Veikko Salomaa,Jorma S. A. Viikari,Jorma S. A. Viikari,Olli T. Raitakari,Olli T. Raitakari,Terho Lehtimäki,Aarno Palotie,Eira Viikari-Juntura,Kirsti Husgafvel-Pursiainen +27 more
TL;DR: The first genome-wide association (GWAS) and meta-analysis of sciatica was performed in Finland as discussed by the authors, where the most promising loci (p < 1x10-6) were replicated in 776 Finnish Sciatica patients and 18,489 controls.
Journal ArticleDOI
Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia
J. Willem L. Tideman,Olavi Pärssinen,Annechien E. G. Haarman,Anthony P Khawaja,Juho Wedenoja,Katie M Williams,Katie M Williams,Ginevra Biino,Xiaohu Ding,Mika Kähönen,Terho Lehtimäki,Olli T. Raitakari,Olli T. Raitakari,Ching-Yu Cheng,Jost B. Jonas,Jost B. Jonas,Terri L. Young,Joan E. Bailey-Wilson,Jugnoo S Rahi,Cathy Williams,Mingguang He,Mingguang He,David A. Mackey,Jeremy A. Guggenheim,UK Biobank Eye,Myopia (Cream) +25 more
TL;DR: In this article, the same authors assess whether a common set of genetic variants are associated with susceptibility to low myopia (LM) and high myopia and hyperopia and find that treatment interventions targeting common genetic risk variants associated with refractive error could be effective against both LM and HM and that individuals with HM inherited a higher number of variants from among the same set of myopia-predisposing alleles compared with individuals with LM.