T
Terho Lehtimäki
Researcher at University of Tampere
Publications - 1375
Citations - 129159
Terho Lehtimäki is an academic researcher from University of Tampere. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 142, co-authored 1304 publications receiving 106981 citations. Previous affiliations of Terho Lehtimäki include Boston University & National Institutes of Health.
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Journal ArticleDOI
Childhood Socioeconomic Disadvantage and Risk of Fatty Liver in Adulthood: The Cardiovascular Risk in Young Finns Study.
Tomi T. Laitinen,Tomi T. Laitinen,Jussi Vahtera,Katja Pahkala,Katja Pahkala,Costan G. Magnussen,Costan G. Magnussen,Costan G. Magnussen,Joel Nuotio,Joel Nuotio,Nina Hutri-Kähönen,Mika Kivimäki,Mika Kivimäki,Terho Lehtimäki,Eero Jokinen,Tomi Laitinen,Päivi Tossavainen,Jaana Pentti,Jaana Pentti,Jorma Viikari,Markus Juonala,Markus Juonala,Olli T. Raitakari,Olli T. Raitakari +23 more
TL;DR: Adulthood risk factors linking childhood socioeconomic disadvantage with fatty liver included waist circumference, body mass index, systolic blood pressure, insulin, physical activity, triglycerides, and red meat consumption.
Journal ArticleDOI
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
William J Young,Najim Lahrouchi,Aaron Isaacs,ThuyVy Duong,Luisa Foco,Farah Abdirahman Ahmed,Jennifer A. Brody,Reem T. Salman,Raymond Noordam,J W Benjamins,Jeffrey Haessler,Leo-Pekka Lyytikäinen,Linda Repetto,Maria Pina Concas,Marten E. van den Berg,Stefan Weiss,Antoine R Baldassari,Traci M. Bartz,James P. Cook,Daniel S. Evans,Rebecca Freudling,Oliver Hines,Jonas L. Isaksen,Honghuang Lin,Hao Mei,Arden Moscati,Martina Müller-Nurasyid,Casia Nursyifa,Yong-chao Qian,Anne Richmond,Carolina Roselli,Kathleen A. Ryan,Eduardo Tarazona-Santos,Sébastien Thériault,Stefan van Duijvenboden,Helen R. Warren,Jie Yao,Dania Raza,Stefanie Aeschbacher,Gustav Ahlberg,Alvaro Alonso,Laura Andreasen,Joshua C. Bis,Eric Boerwinkle,Archie Campbell,Eulalia Catamo,Massimiliano Cocca,Michael J. Cutler,Dawood Darbar,Alessandro De Grandi,A. De Luca,Jun Ding,Christina Ellervik,Patrick T. Ellinor,Stephan B. Felix,Philippe Froguel,Christian Fuchsberger,Martin Gögele,Claus Graff,Mariaelisa Graff,Xiuqing Guo,Torben Hansen,Susan R. Heckbert,Paul L. Huang,Heikki V. Huikuri,Nina Hutri-Kähönen,M. Arfan Ikram,Rebecca D. Jackson,M. Juhani Junttila,Maryam Kavousi,Jan A. Kors,Thiago P. Leal,Rozenn N. Lemaitre,Henry J. Lin,Lars Lind,Allan Linneberg,Simin Liu,Peter W. Macfarlane,Massimo Mangino,Thomas Meitinger,Massimo Mezzavilla,Pashupati P. Mishra,Rebecca N. Mitchell,Nina Mononen,May E. Montasser,Alanna C. Morrison,Matthias Nauck,Victor Nauffal,Pau Navarro,Kjell Nikus,Guillaume Paré,Kristen K. Patton,Giulia Pelliccione,Alan M. Pittman,David J. Porteous,Peter P. Pramstaller,Michael Preuss,Olli T. Raitakari,Alexander P. Reiner,Antonio Luiz Pinho Ribeiro,Kenneth Rice,Lorenz Risch,David Schlessinger,Ulrich Schotten,Claudia Schurmann,Xia Shen,M. Benjamin Shoemaker,Gianfranco Sinagra,Moritz F. Sinner,Elsayed Z. Soliman,Monika Stoll,Konstantin Strauch,Kirill V. Tarasov,Kent D. Taylor,Andrew Tinker,Stella Trompet,André G. Uitterlinden,Uwe Völker,Henry Völzke,Melanie Waldenberger,Lu-Chen Weng,Eric A. Whitsel,James F. Wilson,Christy L. Avery,David Cohen,Adolfo Correa,Francesco Cucca,Marcus Dörr,Sina A. Gharib,Giorgia Girotto,Niels Grarup,Caroline Hayward,Yalda Jamshidi,Marjo-Riitta Järvelin,J. Wouter Jukema,Stefan Kääb,Mika Kähönen,Jørgen K. Kanters,Charles Kooperberg,Terho Lehtimäki,M. Fernanda Lima-Costa,Yongmei Liu,Ruth J. F. Loos,Steven A. Lubitz,Dennis O. Mook-Kanamori,Andrew P. Morris,Jeffrey R. O'Connell,Morten S. Olesen,Michele Orini,Sandosh Padmanabhan,Cristian Pattaro,Annette Peters,Bruce M. Psaty,Jerome I. Rotter,Bruno H. Stricker,P. Van der Harst,Cornelia M. van Duijn,Niek Verweij,Dan E. Arking,Julia Ramirez,Pier D. Lambiase,Nona Sotoodehnia,Borbala Mifsud,Christopher Newton-Cheh,Patricia B. Munroe +164 more
TL;DR: In this paper , the authors identify 177, 156 and 121 independent loci for QT, JT and QRS, including a male-specific X-chromosome locus.
Journal ArticleDOI
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Valérie Turcot,Yingchang Lu,Yingchang Lu,Heather M. Highland,Heather M. Highland,Claudia Schurmann,Anne E. Justice,Rebecca S. Fine,Rebecca S. Fine,Rebecca S. Fine,Jonathan P. Bradfield,Tõnu Esko,Tõnu Esko,Tõnu Esko,Ayush Giri,Mariaelisa Graff,Xiuqing Guo,Audrey E. Hendricks,Audrey E. Hendricks,Tugce Karaderi,Tugce Karaderi,Adelheid Lempradl,Adam E. Locke,Adam E. Locke,Anubha Mahajan,Eirini Marouli,Suthesh Sivapalaratnam,Suthesh Sivapalaratnam,Kristin L. Young,Tamuno Alfred,Mary F. Feitosa,Nicholas G. D. Masca,Nicholas G. D. Masca,Alisa K. Manning,Carolina Medina-Gomez,Poorva Mudgal,Maggie C.Y. Ng,Alexander P. Reiner,Alexander P. Reiner,Sailaja Vedantam,Sailaja Vedantam,Sailaja Vedantam,Sara M. Willems,Thomas W. Winkler,Gonçalo R. Abecasis,Katja K.H. Aben,Dewan S. Alam,Sameer E. Al-Harthi,Sameer E. Al-Harthi,Matthew A. Allison,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Folkert W. Asselbergs,Folkert W. Asselbergs,Paul L. Auer,Beverley Balkau,Lia E. Bang,Inês Barroso,Inês Barroso,Inês Barroso,Lisa Bastarache,Marianne Benn,Marianne Benn,Sven Bergmann,Sven Bergmann,Lawrence F. Bielak,Matthias Blüher,Michael Boehnke,Heiner Boeing,Eric Boerwinkle,Eric Boerwinkle,Carsten A. Böger,Jette Bork-Jensen,Michiel L. Bots,Erwin P. Bottinger,Donald W. Bowden,Ivan Brandslund,Gerome Breen,Gerome Breen,Murray H. Brilliant,Linda Broer,Marco Brumat,Amber A. Burt,Adam S. Butterworth,Peter T. Campbell,Stefania Cappellani,David J. Carey,Eulalia Catamo,Mark J. Caulfield,John C. Chambers,John C. Chambers,John C. Chambers,Daniel I. Chasman,Yii-Der Ida Chen,Rajiv Chowdhury,Cramer Christensen,Audrey Y. Chu,Audrey Y. Chu,Massimiliano Cocca,Francis S. Collins,James P. Cook,Janie Corley,Jordi Corominas Galbany,Amanda J. Cox,Amanda J. Cox,David S. Crosslin,Gabriel Cuellar-Partida,Gabriel Cuellar-Partida,Angela D'Eustacchio,John Danesh,Gail Davies,Gail Davies,Paul I. W. de Bakker,Mark C. H. Groot,Renée de Mutsert,Ian J. Deary,Ian J. Deary,George Dedoussis,Ellen W. Demerath,Martin den Heijer,Anneke I den Hollander,Hester M. den Ruijter,Joe Dennis,Josh C. Denny,Emanuele Di Angelantonio,Fotios Drenos,Fotios Drenos,Mengmeng Du,Mengmeng Du,Marie-Pierre Dubé,Marie-Pierre Dubé,Alison M. Dunning,Douglas F. Easton,Todd L. Edwards,David Ellinghaus,Patrick T. Ellinor,Patrick T. Ellinor,Paul Elliott,Evangelos Evangelou,Evangelos Evangelou,Aliki-Eleni Farmaki,Aliki-Eleni Farmaki,I. Sadaf Farooqi,I. Sadaf Farooqi,Jessica D. Faul,Sascha Fauser,Shuang Feng,Ele Ferrannini,Jean Ferrières,Jose C. Florez,Ian Ford,Myriam Fornage,Oscar H. Franco,Andre Franke,Paul W. Franks,Paul W. Franks,Paul W. Franks,Nele Friedrich,Ruth Frikke-Schmidt,Ruth Frikke-Schmidt,Tessel E. Galesloot,Wei Gan,Ilaria Gandin,Paolo Gasparini,Jane Gibson,Vilmantas Giedraitis,Anette P. Gjesing,Penny Gordon-Larsen,Mathias Gorski,Mathias Gorski,Hans-Jörgen Grabe,Hans-Jörgen Grabe,Struan F.A. Grant,Struan F.A. Grant,Niels Grarup,Helen Griffiths,Megan L. Grove,Vilmundur Gudnason,Stefan Gustafsson,Jeffrey Haessler,Hakon Hakonarson,Hakon Hakonarson,Anke R. Hammerschlag,Torben Hansen,Kathleen Mullan Harris,Tamara B. Harris,Andrew T. Hattersley,Christian Theil Have,Caroline Hayward,Liang He,Liang He,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Andrew C. Heath,Iris M. Heid,Øyvind Helgeland,Øyvind Helgeland,Jussi Hernesniemi,Alex W. Hewitt,Alex W. Hewitt,Alex W. Hewitt,Oddgeir L. Holmen,G. Kees Hovingh,Joanna M. M. Howson,Yao Hu,Paul L. Huang,Jennifer E. Huffman,M. Arfan Ikram,Erik Ingelsson,Erik Ingelsson,Anne U. Jackson,Jan-Håkan Jansson,Gail P. Jarvik,Gorm B. Jensen,Yucheng Jia,Stefan Johansson,Stefan Johansson,Marit E. Jørgensen,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,J. Wouter Jukema,Bratati Kahali,René S. Kahn,Mika Kähönen,Pia R. Kamstrup,Stavroula Kanoni,Jaakko Kaprio,Jaakko Kaprio,Maria Karaleftheri,Sharon L.R. Kardia,Fredrik Karpe,Sekar Kathiresan,Sekar Kathiresan,Frank Kee,Lambertus A. Kiemeney,Eric Kim,Hidetoshi Kitajima,Pirjo Komulainen,Jaspal S. Kooner,Charles Kooperberg,Tellervo Korhonen,Tellervo Korhonen,Tellervo Korhonen,Peter Kovacs,Helena Kuivaniemi,Helena Kuivaniemi,Zoltán Kutalik,Zoltán Kutalik,Kari Kuulasmaa,Johanna Kuusisto,Markku Laakso,Timo A. Lakka,David Lamparter,David Lamparter,Ethan M. Lange,Leslie A. Lange,Claudia Langenberg,Eric B. Larson,Eric B. Larson,Nanette R. Lee,Terho Lehtimäki,Cora E. Lewis,Huaixing Li,Jin Li,Ruifang Li-Gao,Honghuang Lin,Keng-Hung Lin,Li-An Lin,Xu Lin,Lars Lind,Jaana Lindström,Allan Linneberg,Ching-Ti Liu,Dajiang J. Liu,Yongmei Liu,Ken S. Lo,Artitaya Lophatananon,Andrew J. Lotery,Anu Loukola,Jian'an Luan,Steven A. Lubitz,Steven A. Lubitz,Leo-Pekka Lyytikäinen,Satu Männistö,Gaëlle Marenne,Angela L. Mazul,Mark I. McCarthy,Mark I. McCarthy,Roberta McKean-Cowdin,Sarah E. Medland,Karina Meidtner,Lili Milani,Vanisha Mistry,Vanisha Mistry,Paul Mitchell,Karen L. Mohlke,Leena Moilanen,Marie Moitry,Grant W. Montgomery,Grant W. Montgomery,Dennis O. Mook-Kanamori,Carmel Moore,Trevor A. Mori,Andrew D. Morris,Andrew P. Morris,Andrew P. Morris,Martina Müller-Nurasyid,Patricia B. Munroe,Mike A. Nalls,Narisu Narisu,Christopher P. Nelson,Christopher P. Nelson,Matt J. Neville,Sune F. Nielsen,Sune F. Nielsen,Kjell Nikus,Pål R. Njølstad,Pål R. Njølstad,Børge G. Nordestgaard,Børge G. Nordestgaard,Dale R. Nyholt,Dale R. Nyholt,Jeffrey R. O'Connel,Michelle L. O'Donoghue,Loes M. Olde Loohuis,Roel A. Ophoff,Roel A. Ophoff,Katharine R. Owen,Chris J. Packard,Sandosh Padmanabhan,Colin N. A. Palmer,Nicholette D. Palmer,Gerard Pasterkamp,Aniruddh P. Patel,Aniruddh P. Patel,Alison Pattie,Oluf Pedersen,Peggy L. Peissig,Gina M. Peloso,Craig E. Pennell,Markus Perola,James A. Perry,John R. B. Perry,Tune H. Pers,Tune H. Pers,Thomas N. Person,Annette Peters,Eva Rabing Brix Petersen,Patricia A. Peyser,Ailith Pirie,Ozren Polasek,Ozren Polasek,Tinca J. C. Polderman,Hannu Puolijoki,Olli T. Raitakari,Olli T. Raitakari,Asif Rasheed,Rainer Rauramaa,Dermot F. Reilly,Frida Renström,Frida Renström,Myriam Rheinberger,Paul M. Ridker,Paul M. Ridker,John D. Rioux,John D. Rioux,Manuel A. Rivas,Manuel A. Rivas,David J. Roberts,David J. Roberts,David J. Roberts,Neil R. Robertson,Neil R. Robertson,Antonietta Robino,Olov Rolandsson,Igor Rudan,Katherine S. Ruth,Danish Saleheen,Veikko Salomaa,Nilesh J. Samani,Nilesh J. Samani,Yadav Sapkota,Naveed Sattar,Robert E. Schoen,Pamela J. Schreiner,Matthias B. Schulze,Robert A. Scott,Marcelo P. Segura-Lepe,Svati H. Shah,Wayne Huey-Herng Sheu,Wayne Huey-Herng Sheu,Xueling Sim,Xueling Sim,Andrew J. Slater,Kerrin S. Small,Albert V. Smith,Lorraine Southam,Lorraine Southam,Tim D. Spector,Elizabeth K. Speliotes,John M. Starr,Kari Stefansson,Kari Stefansson,Valgerdur Steinthorsdottir,Kathleen Stirrups,Kathleen Stirrups,Konstantin Strauch,Heather M. Stringham,Michael Stumvoll,Liang Sun,Liang Sun,Praveen Surendran,Amy J. Swift,Hayato Tada,Hayato Tada,Katherine E. Tansey,Katherine E. Tansey,Jean-Claude Tardif,Kent D. Taylor,Alexander Teumer,Deborah J. Thompson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Betina H. Thuesen,Anke Tönjes,Gerard Tromp,Gerard Tromp,Stella Trompet,Emmanouil Tsafantakis,Jaakko Tuomilehto,Anne Tybjærg-Hansen,Anne Tybjærg-Hansen,Jonathan Tyrer,Rudolf Uher,André G. Uitterlinden,Matti Uusitupa,Sander W. van der Laan,Cornelia M. van Duijn,Nienke van Leeuwen,Nienke van Leeuwen,Jessica van Setten,Mauno Vanhala,Anette Varbo,Anette Varbo,Tibor V. Varga,Rohit Varma,Digna R. Velez Edwards,Sita H. Vermeulen,Giovanni Veronesi,Henrik Vestergaard,Henrik Vestergaard,Veronique Vitart,Thomas F. Vogt,Uwe Völker,Dragana Vuckovic,Lynne E. Wagenknecht,Mark Walker,Lars Wallentin,Feijie Wang,Carol A. Wang,Shuai Wang,Yiqin Wang,Erin B. Ware,Nicholas J. Wareham,Helen R. Warren,Dawn M. Waterworth,Jennifer Wessel,Harvey D. White,Cristen J. Willer,James G. Wilson,Daniel R. Witte,Andrew R. Wood,Ying Wu,Hanieh Yaghootkar,Jie Yao,Pang Yao,Laura M. Yerges-Armstrong,Laura M. Yerges-Armstrong,Robin Young,Robin Young,Eleftheria Zeggini,Xiaowei Zhan,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Wei Zhao,Wei Zhao,Wei Zhou,Krina T. Zondervan,Krina T. Zondervan,Jerome I. Rotter,John Andrew Pospisilik,Fernando Rivadeneira,Ingrid B. Borecki,Panos Deloukas,Panos Deloukas,Timothy M. Frayling,Guillaume Lettre,Guillaume Lettre,Kari E. North,Cecilia M. Lindgren,Cecilia M. Lindgren,Joel N. Hirschhorn,Ruth J. F. Loos +506 more
TL;DR: In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled and this error has now been corrected in the HTML and PDF versions of the article.
Journal ArticleDOI
Tissue inhibitor of matrix metalloproteinases 4 (TIMP4) in a population of young adults: relations to cardiovascular risk markers and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study.
Mervi Oikonen,Maria Wendelin-Saarenhovi,Niina Siitonen,Annele Sainio,Markus Juonala,Mika Kähönen,Leo-Pekka Lyytikäinen,Ilkka Seppälä,Terho Lehtimäki,Jorma Viikari,Hannu Järveläinen,Olli T. Raitakari +11 more
TL;DR: In young apparently healthy adults, circulating TIMP4 concentration was independently and inversely associated with cIMT, a marker of vascular structure and function, a sign of atherosclerosis and traditional cardiovascular risk factors.
Journal ArticleDOI
Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study
Niku Oksala,Ilkka Seppälä,Jussi Hernesniemi,Leo-Pekka Lyytikäinen,Mika Kähönen,Kari-Matti Mäkelä,Antti Reunanen,Antti Jula,Mika Ala-Korpela,Terho Lehtimäki +9 more
TL;DR: EFW approach-derived HDL2-C, apoA-I, apOB/apoA- I, and VLDL-TG improve prediction of non-fatal cardiovascular events, and apoB of cardiovascular mortality, and can be utilized for risk estimation in a working age population without extra cost.