Institution
Bulgarian Academy of Sciences
Government•Sofia, Bulgaria•
About: Bulgarian Academy of Sciences is a government organization based out in Sofia, Bulgaria. It is known for research contribution in the topics: Catalysis & Coupling constant. The organization has 17989 authors who have published 36276 publications receiving 642820 citations. The organization is also known as: Bulgarian Academy of Sciences,簡稱:BAS & Balgarska Akademiya na Naukite.
Papers published on a yearly basis
Papers
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TL;DR: Plant and animal assays are differentially responsive to some pesticides, and these differences may be due to metabolism and their responses to mitotic spindle disruption, as indicated by data on chromosomal aberrations and micronuclei.
Abstract: The genotoxicities of the herbicides Roundup (glyphosate), Stomp (pendimethaline) and Reglone (diquat), were compared in plant (Crepis capillaris L.) and mouse bone marrow test systems using chromosomal aberrations and micronuclei. Roundup did not induce chromosomal aberrations or micronuclei in either test system. Reglone also did not induce chromosomal aberrations in either test system; however, it increased micronucleus frequency in both plant cells and mouse bone marrow polychromatic erythrocytes (PCEs). The responses of the two test systems to Stomp were quite different. Stomp did not induce chromosomal aberrations in the plant cells, but increased their incidence in mouse cells; Stomp increased the frequency of micronuclei in both test systems. The induction of micronuclei in plant cells may have been due to the spindle-destroying effect of the herbicide, since all concentrations of Stomp produced C-mitoses. The increased chromosomal aberration frequency in mouse bone marrow cells observed at later sampling times after administration of Stomp into animals suggests that the induction of aberrations may be due to biosynthesis of genotoxic metabolites. This conclusion was supported by the coincidence between the frequencies of chromosomal aberrations and of micronucleated PCEs in mouse cells. These data indicate that plant and animal assays are differentially responsive to some pesticides, and these differences may be due to metabolism and their responses to mitotic spindle disruption.
109 citations
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TL;DR: The inherent stability and the stabilisation of these nutritionally valuable polyunsaturated fatty acids are reviewed.
Abstract: Currently there is great interest in dietary n-3 fatty acids to promote health. The food industry aims to produce food products enriched in α-linolenic acid (Ln), eicosapentaenoic acid (EPA) and/or docosahexaenoic acid (DHA) to reduce some of the physiological effects of linoleic acid (L), the major polyunsaturated fatty acid in our diet. However, the goal is hampered by the susceptibility of the n-3 fatty acids to oxidation. As a result the sensory and nutritional quality of such foods deteriorates. Lipid scientists therefore have to find a way to stabilise these fatty acids. Innovative technologies to protect n-3 polyunsaturates using antioxidants, adequate preparation, refining and packaging of the oil are needed. In this paper we review the inherent stability and the stabilisation of these nutritionally valuable polyunsaturated fatty acids.
109 citations
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TL;DR: The growth and carotenoid biosynthesis of the yeast Rhodotorula glutinis was studied by cocultivation with Lactobacillus helveticus in cheese ultrafiltrate containing 3.9% and 7.1% lactose, and a maximum production was reached at an early stationary phase.
Abstract: The growth and carotenoid biosynthesis of the yeast Rhodotorula glutinis was studied by cocultivation with Lactobacillus helveticus in cheese ultrafiltrate containing 3.9% and 7.1% lactose. By growing this mixed culture in a 15-L fermentor MBR AG (Switzerland) at an air flow rate of 0.5 L/L min and agitation at 220 rpm for 6 days, a total yield of carotenoids of 268 μg/g dry cells wasobtained. Carotenoids were formed almost parallel with the cell growth, anda maximum production was reached at an early stationary phase. A high-performance liquid chromatographic system (HPLC) permitting simultaneous determination of major carotenoid pigments was used. The three main pigments (torularhodin, β-carotene, and torulene) were formed in Rhodotorula glutinis, and reached a maximum concentration as follows: 182.0, 43.9, 23.0 μg,g dry cells. © 1994 John Wiley & Sons, Inc.
109 citations
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Max Planck Society1, Heidelberg University2, Katholieke Universiteit Leuven3, CERN4, University of Liverpool5, University of Edinburgh6, University of the West of Scotland7, Sofia University8, Technische Universität Darmstadt9, Bulgarian Academy of Sciences10, Petersburg Nuclear Physics Institute11, University of Manchester12, Technische Universität München13, Spanish National Research Council14, Frankfurt Institute for Advanced Studies15, University of Surrey16, Lund University17, Australian National University18, University of Mainz19, Complutense University of Madrid20, University of Helsinki21, University of Jyväskylä22, Goethe University Frankfurt23, Ludwig Maximilian University of Munich24, Michigan State University25, Chinese Academy of Sciences26, University of York27, Chalmers University of Technology28, University of Groningen29, Daresbury Laboratory30, Beihang University31, University of Warsaw32, University of Cologne33, Aarhus University34, Columbia University35, Lawrence Livermore National Laboratory36, Stockholm University37, Weizmann Institute of Science38, Helmholtz Institute Jena39, University of Jena40, Saitama University41, Dresden University of Technology42
TL;DR: In this article, the authors proposed to install a storage ring at an ISOL-type radioactive beam facility for the first time, which can provide a capability for experiments with stored secondary beams that is unique in the world.
Abstract: We propose to install a storage ring at an ISOL-type radioactive beam facility for the first time. Specifically, we intend to setup the heavy-ion, low-energy ring TSR at the HIE-ISOLDE facility in CERN, Geneva. Such a facility will provide a capability for experiments with stored secondary beams that is unique in the world. The envisaged physics programme is rich and varied, spanning from investigations of nuclear ground-state properties and reaction studies of astrophysical relevance, to investigations with highly-charged ions and pure isomeric beams. The TSR might also be employed for removal of isobaric contaminants from stored ion beams and for systematic studies within the neutrino beam programme. In addition to experiments performed using beams recirculating within the ring, cooled beams can also be extracted and exploited by external spectrometers for high-precision measurements. The existing TSR, which is presently in operation at the Max-Planck Institute for Nuclear Physics in Heidelberg, is well-suited and can be employed for this purpose. The physics cases as well as technical details of the existing ring facility and of the beam and infrastructure requirements at HIE-ISOLDE are discussed in the present technical design report.
109 citations
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TL;DR: The most recent studies on different approaches for preparation of antibacterial fibrous materials from chitosan and its derivatives such as electrosp spinning, coating, and electrospinning-electrospraying, loading of drugs or bioactive nanoparticles are summarized.
Abstract: Chitosan is non-toxic, biocompatible, and biodegradable polysaccharide from renewable resources, known to have inherent antibacterial activity, which is mainly due to its polycationic nature. The combining of all assets of chitosan and its derivatives with the unique properties of electrospun nanofibrous materials is a powerful strategy to prepare new materials that can find variety of biomedical applications. In this article the most recent studies on different approaches for preparation of antibacterial fibrous materials from chitosan and its derivatives such as electrospinning, coating, and electrospinning-electrospraying, loading of drugs or bioactive nanoparticles are summarized.
109 citations
Authors
Showing all 18074 results
Name | H-index | Papers | Citations |
---|---|---|---|
Dimitri Bourilkov | 134 | 1489 | 96884 |
Eduardo De Moraes Gregores | 133 | 1454 | 92464 |
Georgi Sultanov | 132 | 1493 | 93318 |
Plamen Iaydjiev | 131 | 1285 | 87958 |
Pedro G Mercadante | 129 | 1331 | 86378 |
Jordan Damgov | 129 | 1195 | 85490 |
Roumyana Hadjiiska | 126 | 1003 | 73091 |
Mircho Rodozov | 124 | 972 | 70519 |
Cesar Augusto Bernardes | 124 | 965 | 70889 |
Viktor Matveev | 123 | 1212 | 73939 |
Ayda Beddall | 120 | 816 | 67063 |
Andrey Marinov | 119 | 893 | 57183 |
Mariana Vutova | 117 | 606 | 56698 |
Lester Packer | 112 | 751 | 63116 |
Patrick Couvreur | 111 | 678 | 56735 |