Institution
Griffith University
Education•Brisbane, Queensland, Australia•
About: Griffith University is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Context (language use). The organization has 13830 authors who have published 49318 publications receiving 1420865 citations.
Topics: Population, Context (language use), Poison control, Health care, Tourism
Papers published on a yearly basis
Papers
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TL;DR: The Australian monsoon is a component of a single global climate system, characterized by a dominant equator-spanning Hadley cell, and future palaeoecological and phylogenetic investigations will illuminate the evolution of the AMT biome.
Abstract: Aim This paper reviews the biogeography of the Australian monsoon tropical
biome to highlight general patterns in the distribution of a range of organisms
and their environmental correlates and evolutionary history, as well as to identify
knowledge gaps.
Location Northern Australia, Australian Monsoon Tropics (AMT). The AMT
is defined by areas that receive more than 85% of rainfall between November
and April.
Methods Literature is summarized, including the origin of the monsoon
climate, present-day environment, biota and habitat types, and phylogenetic and
geographical relationships of selected organisms.
Results Some species are widespread throughout the AMT while others are
narrow-range endemics. Such contrasting distributions correspond to presentday
climates, hydrologies (particularly floodplains), geological features (such as
sandstone plateaux), fire regimes, and vegetation types (ranging from rain forest
to savanna). Biogeographical and phylogenetic studies of terrestrial plants
(e.g. eucalypts) and animals (vertebrates and invertebrates) suggest that distinct
bioregions within the AMT reflect the aggregated effects of landscape and
environmental history, although more research is required to determine and
refine the boundaries of biogeographical zones within the AMT. Phylogenetic
analyses of aquatic organisms (fishes and prawns) suggest histories of associations
with drainage systems, dispersal barriers, links to New Guinea, and the existence
of Lake Carpentaria, now submerged by the Gulf of Carpentaria. Complex
adaptations to the landscape and climate in the AMT are illustrated by a number
of species.
Main conclusions The Australian monsoon is a component of a single global
climate system, characterized by a dominant equator-spanning Hadley cell.
Evidence of hot, seasonally moist climates dates back to the Late Eocene, implying
that certain endemic elements of the AMT biota have a long history. Vicariant
differentiation is inferred to have separated the Kimberley and Arnhem Land
bioregions from Cape York Peninsula/northern Queensland. Such older patterns
are overlaid by younger events, including dispersal from Southeast Asia, and
range expansions and contractions. Future palaeoecological and phylogenetic
investigations will illuminate the evolution of the AMT biome. Understanding the
biogeography of the AMT is essential to provide a framework for ecological
studies and the sustainable development of the region.
286 citations
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TL;DR: In this article, the authors examined corporate social disclosure practices in Malaysian and Singapore companies and found that a positive correlation existed between corporate size and CSD (Trotman, 1979), as well as the relationship between CSD and industry groupings (Guthrie, 1983).
Abstract: Most studies on corporate social disclosure (CSD) have focused on the industrialised countries of Europe, United States and Australia (for example, Dierkes & Preston, 1977; Beresford & Cowen, 1979; Brockhoff, 1979). Even international comparative studies of CSD concentrated on analyses of the similarities and differences of CSD practices in these countries (for example, Schoenfeld, 1978; Ernst & Ernst, 1979; Guthrie & Parker, 1988). There is however, a paucity of CSD literature on practices in the developing countries. The purpose of this paper is to address this imbalance by examining CSD practices in Malaysian and Singapore companies. Within the CSD literature on developed countries, there is evidence that a positive correlation existed between corporate size and CSD (Trotman, 1979). More recently additional evidence was found concerning the themes, methods, extent of CSD in the annual reports, as well as the relationship between CSD and industry groupings (Guthrie, 1983). In the few studies available on developing countries, Teoh & Thong (1984) and Singh & Ahuja (1983) f ound broadly similar evidence. The data reported in this paper is intended to be purely descriptive. The paper explored the CSD characteristics mentioned above and assessed the
286 citations
Victor Chang Cardiac Research Institute1, University of New South Wales2, Boston Children's Hospital3, Federal University of Rio de Janeiro4, University of Cincinnati5, Children's Hospital at Westmead6, University of Sydney7, Kangwon National University8, St. Vincent's Health System9, Griffith University10
TL;DR: These findings are the first to link TBX20 mutations to human pathology and provide insights into how mutation of different genes in an interactive regulatory circuit lead to diverse clinical phenotypes, with implications for diagnosis, genetic screening, and patient follow-up.
Abstract: The T-box family transcription factor gene TBX20 acts in a conserved regulatory network, guiding heart formation and patterning in diverse species. Mouse Tbx20 is expressed in cardiac progenitor cells, differentiating cardiomyocytes, and developing valvular tissue, and its deletion or RNA interference-mediated knockdown is catastrophic for heart development. TBX20 interacts physically, functionally, and genetically with other cardiac transcription factors, including NKX2-5, GATA4, and TBX5, mutations of which cause congenital heart disease (CHD). Here, we report nonsense (Q195X) and missense (I152M) germline mutations within the T-box DNA-binding domain of human TBX20 that were associated with a family history of CHD and a complex spectrum of developmental anomalies, including defects in septation, chamber growth, and valvulogenesis. Biophysical characterization of wild-type and mutant proteins indicated how the missense mutation disrupts the structure and function of the TBX20 T-box. Dilated cardiomyopathy was a feature of the TBX20 mutant phenotype in humans and mice, suggesting that mutations in developmental transcription factors can provide a sensitized template for adult-onset heart disease. Our findings are the first to link TBX20 mutations to human pathology. They provide insights into how mutation of different genes in an interactive regulatory circuit lead to diverse clinical phenotypes, with implications for diagnosis, genetic screening, and patient follow-up.
286 citations
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TL;DR: The findings show that endometriosis impacts negatively on different aspects of women’s lives, and a better understanding of these findings could help to decrease the negative impact of endometRIosis by guiding service delivery and future research to meet more effectively the needs of women and teenagers with this condition.
Abstract: Background: This study aimed to explore women’s experiences of the impact of endometriosis and whether there are differences across three age groups. Methods: A qualitative descriptive design was conducted using semi-structured focus group discussions with 35 Australian women with endometriosis, in three age groups. All tape-recorded discussions were transcribed verbatim and read line by line to extract meaningful codes and categories using NVivo 9 software through a thematic analysis approach. Categories were then clustered into meaningful themes. Results: Participants’ ages ranged from 17 to 53 years and had a history of 2 to 40 years living with endometriosis, with an average delay time to diagnosis of 8.1 years. Two main themes emerged: (1) experiences of living with endometriosis, and (2) impact of endometriosis on women’s lives, with 14 discrete categories. The results showed similarities and differences of the impact between the three age groups. The most highlighted impacts were on marital/sexual relationships, social life, and on physical and psychological aspects in all three age groups, but with different orders of priority. Education was the second most highlighted for the 16–24 years, life opportunities and employment for the 25–34 years; and financial impact for those 35 years and above. Conclusions: Our findings show that endometriosis impacts negatively on different aspects of women’s lives. A better understanding of these findings could help to decrease the negative impact of endometriosis by guiding service delivery and future research to meet more effectively the needs of women and teenagers with this condition.
286 citations
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TL;DR: Recent data regarding mechanisms of bacterial translocation from the nasal mucosa to the brain are focused on, which represents a little explored pathway of bacterial invasion but has been proposed as being particularly important in explaining how infection with Burkholderia pseudomallei can result in melioidosis encephalomyelitis.
Abstract: The brain is well protected against microbial invasion by cellular barriers, such as the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells within the central nervous system (CNS) are capable of producing an immune response against invading pathogens. Nonetheless, a range of pathogenic microbes make their way to the CNS, and the resulting infections can cause significant morbidity and mortality. Bacteria, amoebae, fungi, and viruses are capable of CNS invasion, with the latter using axonal transport as a common route of infection. In this review, we compare the mechanisms by which bacterial pathogens reach the CNS and infect the brain. In particular, we focus on recent data regarding mechanisms of bacterial translocation from the nasal mucosa to the brain, which represents a little explored pathway of bacterial invasion but has been proposed as being particularly important in explaining how infection with Burkholderia pseudomallei can result in melioidosis encephalomyelitis.
285 citations
Authors
Showing all 14162 results
Name | H-index | Papers | Citations |
---|---|---|---|
Rasmus Nielsen | 135 | 556 | 84898 |
Claudiu T. Supuran | 134 | 1973 | 86850 |
Jeffrey D. Sachs | 130 | 692 | 86589 |
David Smith | 129 | 2184 | 100917 |
Michael R. Green | 126 | 537 | 57447 |
John J. McGrath | 120 | 791 | 124804 |
E. K. U. Gross | 119 | 1154 | 75970 |
David M. Evans | 116 | 632 | 74420 |
Mike Clarke | 113 | 1037 | 164328 |
Wayne Hall | 111 | 1260 | 75606 |
Patrick J. McGrath | 107 | 681 | 51940 |
Peter K. Smith | 107 | 855 | 49174 |
Erko Stackebrandt | 106 | 633 | 68201 |
Phyllis Butow | 102 | 731 | 37752 |
John Quackenbush | 99 | 427 | 67029 |