Showing papers by "Griffith University published in 2011"
Stephen Sawcer1, Garrett Hellenthal2, Matti Pirinen2, Chris C. A. Spencer2 +262 more•Institutions (67)
TL;DR: In this article, a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, they have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci.
Abstract: Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis.
2,511 citations
TL;DR: In this paper, the authors explored the role of four key factors that influence perceptions of trust and consumer choice within a hotel context, and found that consumers tend to rely on easy-to-process information, when evaluating a hotel based upon reviews.
1,250 citations
TL;DR: The dust cycle is an integral part of the Earth system as discussed by the authors, it carries organic material, contributes directly to the carbon cycle and carries iron which is vital to ocean productivity and the ocean-atmosphere CO2 exchange.
768 citations
University of Copenhagen1, University of California, Berkeley2, Technical University of Denmark3, Estonian Biocentre4, Imperial College London5, University of Cambridge6, Chinese Academy of Sciences7, Stanford University8, Murdoch University9, National Autonomous University of Mexico10, University of Western Australia11, Kitasato University12, University of Bern13, University of Chicago14, University of Toulouse15, Leiden University16, University College London17, Griffith University18, Max Planck Society19, University of British Columbia20, Estonian Academy of Sciences21
TL;DR: It is shown that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago, which is separate from the one that gave rise to modern Asians 25, thousands of years ago.
Abstract: We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.
656 citations
TL;DR: An experiment determined the trajectories of single photons through a two-slit interferometer and reconstructed these trajectories by performing a weak measurement of the photon momentum, postselected according to the result of a strong measurement of photon position in a series of planes.
Abstract: A consequence of the quantum mechanical uncertainty principle is that one may not discuss the path or "trajectory" that a quantum particle takes, because any measurement of position irrevocably disturbs the momentum, and vice versa. Using weak measurements, however, it is possible to operationally define a set of trajectories for an ensemble of quantum particles. We sent single photons emitted by a quantum dot through a double-slit interferometer and reconstructed these trajectories by performing a weak measurement of the photon momentum, postselected according to the result of a strong measurement of photon position in a series of planes. The results provide an observationally grounded description of the propagation of subensembles of quantum particles in a two-slit interferometer.
624 citations
TL;DR: Strong evidence is provided that BA plateaus 1 to 2 years earlier than BMC, substantiate the importance of the circumpubertal years for accruing bone mineral, and provides strong evidence that peak bone mass occurs by the end of the second or early in the third decade of life.
Abstract: Bone area (BA) and bone mineral content (BMC) were measured from childhood to young adulthood at the total body (TB), lumbar spine (LS), total hip (TH), and femoral neck (FN). BA and BMC values were expressed as a percentage of young-adult values to determine if and when values reached a plateau. Data were aligned on biological ages [years from peak height velocity (PHV)] to control for maturity. TB BA increased significantly from -4 to +4 years from PHV, with TB BMC reaching a plateau, on average, 2 years later at +6 years from PHV (equates to 18 and 20 years of age in girls and boys, respectively). LS BA increased significantly from -4 years from PHV to +3 years from PHV, whereas LS BMC increased until +4 from PHV. FN BA increased between -4 and +1 years from PHV, with FN BMC reaching a plateau, on average, 1 year later at +2 years from PHV. In the circumpubertal years (-2 to +2 years from PHV): 39% of the young-adult BMC was accrued at the TB in both males and females; 43% and 46% was accrued in males and females at the LS and TH, respectively; 33% (males and females) was accrued at the FN. In summary, we provide strong evidence that BA plateaus 1 to 2 years earlier than BMC. Depending on the skeletal site, peak bone mass occurs by the end of the second or early in the third decade of life. The data substantiate the importance of the circumpubertal years for accruing bone mineral.
537 citations
TL;DR: A companion effect of marine climate change is ocean acidification, which may pose a significant threat through its capacity to alter larval behaviour and impair sensory capabilities, which in turn impacts on population replenishment and connectivity patterns of marine fishes.
Abstract: Seasonal change in temperature has a profound effect on reproduction in fish. Increasing temperatures cue reproductive development in spring-spawning species, and falling temperatures stimulate reproduction in autumn-spawners. Elevated temperatures truncate spring spawning, and delay autumn spawning. Temperature increases will affect reproduction, but the nature of these effects will depend on the period and amplitude of the increase and range from phase-shifting of spawning to complete inhibition of reproduction. This latter effect will be most marked in species that are constrained in their capacity to shift geographic range. Studies from a range of taxa, habitats and temperature ranges all show inhibitory effects of elevated temperature albeit about different environmental set points. The effects are generated through the endocrine system, particularly through the inhibition of ovarian oestrogen production. Larval fishes are usually more sensitive than adults to environmental fluctuations, and might be especially vulnerable to climate change. In addition to direct effects on embryonic duration and egg survival, temperature also influences size at hatching, developmental rate, pelagic larval duration and survival. A companion effect of marine climate change is ocean acidification, which may pose a significant threat through its capacity to alter larval behaviour and impair sensory capabilities. This in turn impacts on population replenishment and connectivity patterns of marine fishes.
514 citations
TL;DR: Despite consensus that development shapes every aspect of coping, studies of age differences in coping have proven difficult to integrate, primarily because they examine largely unselected age grou... as discussed by the authors, 2015
Abstract: Despite consensus that development shapes every aspect of coping, studies of age differences in coping have proven difficult to integrate, primarily because they examine largely unselected age grou...
498 citations
TL;DR: Owing to the high risk of overweight adolescents becoming obese adults, the engagement of children and adolescents in physical activity and sport is a fundamental goal of obesity prevention.
Abstract: Globally, obesity is affecting an increasing proportion of children. Physical activity plays an important role in the prevention of becoming overweight and obese in childhood and adolescence, and reducing the risk of obesity in adulthood. Puberty and the following adolescent period are acknowledged as particularly vulnerable times for the development of obesity due to sexual maturation and, in many individuals, a concomitant reduction in physical activity. In many Western settings, a large proportion of children and adolescents do not meet recommended physical activity guidelines and, typically, those who are more physically active have lower levels of body fat than those who are less active. Active behaviours have been displaced by more sedentary pursuits which have contributed to reductions in physical activity energy expenditure. Without appropriate activity engagement there is an increased likelihood that children will live less healthy lives than their parents. Owing to the high risk of overweight adolescents becoming obese adults, the engagement of children and adolescents in physical activity and sport is a fundamental goal of obesity prevention.
448 citations
TL;DR: The authors argue that being intimately inside one's field does offer significant advantages, however, there remain elements of insider research still underdeveloped, such as how one goes about negotiating previously established friendships and intimate relationships.
Abstract: Favoured by ethnographers with some degree of closeness to the culture they wish to examine, the cultural participant as insider researcher has become relatively commonplace across the humanities. A large body of methodological literature now exists on this, highlighting the advantages and some of the dilemmas of conducting insider research. This literature is not exhaustive, as there remain elements of insider research still underdeveloped, such as how one goes about negotiating previously established friendships and intimate relationships in this context. Indeed, what are the benefits and dilemmas engendered by such negotiations? Drawing on existing scholarly accounts of field-based friendship and the author’s experiences of researching queer culture as an insider, this article addresses these questions in relation to the author’s field of inquiry and to social research paradigms more broadly. Subsequently, it argues that while being intimately inside one’s field does offer significant advantages, it al...
430 citations
TL;DR: Osteomacs are established as participants in intramembranous bone healing and as targets for primary anabolic bone therapies in a mouse tibial injury model.
Abstract: The FANTOM5 consortium used cap analysis of gene expression (CAGE) to analyze the time course of gene expression over development from 11 days postcoitum (dpc) to adult in 16 developing organs and the whole body of the mouse. Every tissue in the body contains a large number of resident macrophages that initially infiltrate the embryo from the yolk sac. These cells contribute to organogenesis, and their functions diversify during development as they acquire tissue-specific adaptations. In each of the FANTOM5 time courses, the expression of known macrophage-specific genes, including CSF1 receptor (Csf1r), epidermal growth factor-like module-containing mucin-like hormone receptor-like 1 (Emr1), and mer receptor tyrosine kinase (Mertk), was readily detectable and increased with time. We reasoned that genes expressed by macrophages would be strongly correlated in their expression with these known markers and might vary between tissues. We used the network analysis tool, Miru, to extract the sets of coexpressed genes from the time course and identified a core set of coexpressed genes attributable to embryonic macrophages, including some, such as dehydrogenase/reductase 3 (Dhrs3), that may have unique functions in development. The FANTOM5 data also detected the appearance of tissue-specific macrophage-expressed genes, such as T cell Ig and mucin domain-containing 4 (Timd4) and V-set and Ig domain-containing 4 (Vsig4) in liver and sialic acid-binding Ig-like lectin 5 (Siglec5) in lung, and confirmed that macrophage content increases with time in each organ as the proliferative phases end, and tissue-specific gene-expression increases. The FANTOM5 data are available on a comprehensive browser (http://fantom.gsc.riken.jp/zenbu/), which provides a resource for the study of macrophage transcriptional regulation and roles in mouse development.
TL;DR: The rationale for the design and use of gold compounds that have specific and selective targets in cells to alleviate the symptoms of a range of human diseases is discussed and discoveries to show that gold compounds can be developed to become versatile and powerful drugs for diseases caused by dysfunction of selenol and thiol containing proteins are summarised.
Abstract: The application of gold in medicine is traceable for several thousand years and Au(I) compounds have been used clinically to treat rheumatoid arthritis since the last century. Recently research into gold-based drugs for a range of human diseases has seen a renaissance. Old as well as new Au(I) and Au(III) compounds have been used and designed with an aim of targeting cellular components that are implicated in the onset or progression of cancers, rheumatoid arthiritis, viral and parasitic diseases. In addition, new disease targets have been found for gold compounds that have given insight into the mechanism of action of these compounds, as well as in the molecular pathophysiology of human diseases. Here we discuss the rationale for the design and use of gold compounds that have specific and selective targets in cells to alleviate the symptoms of a range of human diseases. We summarise the most recent findings in this research and our own discoveries to show that gold compounds can be developed to become versatile and powerful drugs for diseases caused by dysfunction of selenol and thiol containing proteins.
TL;DR: Characteristics of psychology that cross content domains and that make the field well suited for providing an understanding of climate change and addressing its challenges are highlighted and ethical imperatives for psychologists' involvement are considered.
Abstract: Global climate change poses one of the greatest challenges facing humanity in this century. This article, which introduces the American Psychologist special issue on global climate change, follows from the report of the American Psychological Association Task Force on the Interface Between Psychology and Global Climate Change. In this article, we place psychological dimensions of climate change within the broader context of human dimensions of climate change by addressing (a) human causes of, consequences of, and responses (adaptation and mitigation) to climate change and (b) the links between these aspects of climate change and cognitive, affective, motivational, interpersonal, and organizational responses and processes. Characteristics of psychology that cross content domains and that make the field well suited for providing an understanding of climate change and addressing its challenges are highlighted. We also consider ethical imperatives for psychologists' involvement and provide suggestions for ways to increase psychologists' contribution to the science of climate change.
TL;DR: While healing showed similar characteristics with bone resorptive and appositional events for both SLActive and SLA surfaces between 7 and 42 days, the degree of osseointegration after 2 and 4 weeks was superior for the SLActive compared with the SLA surface.
Abstract: To evaluate the rate and degree of osseointegration at chemically modified moderately rough, hydrophilic (SLActive) and moderately rough, hydrophobic (SLA) implant surfaces during early phases of healing in a human model.
TL;DR: The results of the oracle experiments show that accurate phase spectrum estimates can considerably contribute towards speech quality, as well as that the use of mismatched analysis windows in the computation of the magnitude and phase spectra provides significant improvements in both objective and subjective speech quality.
TL;DR: In this article, a meta-analysis was performed to quantify the association between antisocial behavior (ASB) and performance on neuropsychological executive functioning (EF) measures, which indicated that a robust association exists between ASB and poor EF that held across studies with varied methodological approaches.
Abstract: A meta-analysis was performed to quantify the association between antisocial behavior (ASB) and performance on neuropsychological executive functioning (EF) measures. This meta-analysis built on Morgan and Lilienfeld's (2000) meta-analysis of the same topic by including recently published studies and by examining a wider range of EF measures. A total of 126 studies involving 14,786 participants were included in the analyses. Antisocial groups performed significantly worse on measures of EF compared with controls, with a grand mean effect size of d= .44. Significant variation occurred in the magnitude of effect sizes calculated across studies. The largest effect sizes were found for criminality (d= .61) and externalizing behavior disorder (d= .54) ASB groups, whereas the smallest effect sizes were found for antisocial personality disorder (d= .19) groups. Larger differences in EF performance were observed across studies involving participants from correctional settings and with comorbid attention deficit and hyperactivity problems. Overall, the results indicated that a robust association exists between ASB and poor EF that held across studies with varied methodological approaches. The methodological issues in the research literature and the implications of the meta-analysis results are discussed, and the directions for future research are proposed.
TL;DR: Results indicated that residents with very positive environmental and water conservation attitudes consumed significantly less water in total and across the behaviourally influenced end uses of shower, clothes washer, irrigation and tap, than those with moderately positive attitudinal concern.
Brigham and Women's Hospital1, University Hospital Bonn2, Wellcome Trust Sanger Institute3, University of Helsinki4, Leiden University5, National Institutes of Health6, Griffith University7, Helsinki University Central Hospital8, Ludwig Maximilian University of Munich9, University of Ulm10, French Institute of Health and Medical Research11
TL;DR: In a population-based genome-wide analysis including 5,122 migraineurs and 18,108 non-migraineurs, rs2651899, rs10166942 and rs11172113 were among the top seven associations with migraine, plausibly linking both genes to migraine pathophysiology.
Abstract: Migraine is a common, heterogeneous and heritable neurological disorder. Its pathophysiology is incompletely understood, and its genetic influences at the population level are unknown. In a population-based genome-wide analysis including 5,122 migraineurs and 18,108 non-migraineurs, rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8) and rs11172113 (12q13.3, LRP1) were among the top seven associations (P < 5 × 10(-6)) with migraine. These SNPs were significant in a meta-analysis among three replication cohorts and met genome-wide significance in a meta-analysis combining the discovery and replication cohorts (rs2651899, odds ratio (OR) = 1.11, P = 3.8 × 10(-9); rs10166942, OR = 0.85, P = 5.5 × 10(-12); and rs11172113, OR = 0.90, P = 4.3 × 10(-9)). The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache. None of the three SNP associations was preferential for migraine with aura or without aura, nor were any associations specific for migraine features. TRPM8 has been the focus of neuropathic pain models, whereas LRP1 modulates neuronal glutamate signaling, plausibly linking both genes to migraine pathophysiology.
TL;DR: The authors’ studies on schistosomiasis have received financial support from various sources including: the UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases.
Abstract: The authors’ studies on schistosomiasis have received financial support from various sources including: the UNICEF/UNDP/World Bank/WHO Special Program for Research and Training in Tropical Diseases; the National Health and Medical Research Council of Australia; the Wellcome Trust (UK); the Sandler Foundation (USA); the Dana Foundation (USA); and the National Institute of Allergy and Infectious Diseases.
TL;DR: There is scope for use of stress responses to be used as a measure of environmental quality but only if the basic response to environmental stress is well understood first.
TL;DR: In this article, the UN Security Council authorized the use of force to protect civilians in Libya and this was the first time that the Council has ever authorized the invasion of a functioning state for such purposes International society's relatively decisive responses to recent crises in Cote d'Ivoire and Libya has provoked significant commentary, suggesting that something has changed about the way the world responds to violence against civilians.
Abstract: In March 2011, the UN Security Council authorized the use of force to protect civilians in Libya This was the first time that the Council has ever authorized the invasion of a functioning state for such purposes International society's relatively decisive responses to recent crises in Cote d'Ivoire and Libya has provoked significant commentary, suggesting that something has changed about the way the world responds to violence against civilians Focusing on these two cases, this article examines the changing practice of the UN Security Council It argues that we are seeing the emergence of a new politics of protection, but that this new politics has been developing over the past decade Four things are new about this politics of protection: protecting civilians from harm has become a focus for international engagement; the UN Security Council has proved itself willing to authorize the use of force for protection purposes; regional organizations have begun to play the role of ‘gatekeeper’; and major powers have exhibited a determination to work through the Security Council where possible However, the cases of Cote d'Ivoire and Libya also help to highlight some key challenges that might halt or reverse progress Notably, states differ in the way they interpret mandates; questions are being asked about the UN's authority to act independently of specific Security Council authorizations; the overlap of regional organizations sometimes sends conflicting messages to the Security Council; and there remains a range of difficult operational questions about how to implement protection mandates With these in mind, this article concludes with some suggestions about how the future challenges might be navigated in order to maintain the progress that has been made in the past decade
TL;DR: In this article, the authors analyzed how different combinations of CO2 and fishing pressure on herbivores will affect the ecological resilience of a simplified benthic reef community, as defined by its capacity to maintain and recover to coral-dominated states.
Abstract: Ocean warming and acidification from increasing levels of atmospheric CO2 represent major global threats to coral reefs, and are in many regions exacerbated by local-scale disturbances such as overfishing and nutrient enrichment. Our understanding of global threats and local-scale disturbances on reefs is growing, but their relative contribution to reef resilience and vulnerability in the future is unclear. Here, we analyse quantitatively how different combinations of CO2 and fishing pressure on herbivores will affect the ecological resilience of a simplified benthic reef community, as defined by its capacity to maintain and recover to coral-dominated states. We use a dynamic community model integrated with the growth and mortality responses for branching corals (Acropora) and fleshy macroalgae (Lobophora). We operationalize the resilience framework by parameterizing the response function for coral growth (calcification) by ocean acidification and warming, coral bleaching and mortality by warming, macroalgal mortality by herbivore grazing and macroalgal growth via nutrient loading. The model was run for changes in sea surface temperature and water chemistry predicted by the rise in atmospheric CO2 projected from the IPCC’s fossil-fuel intensive A1FI scenario during this century. Results demonstrated that severe acidification and warming alone can lower reef resilience (via impairment of coral growth and increased coral mortality) even under high grazing intensity and low nutrients. Further, the threshold at which herbivore overfishing (reduced grazing) leads to a coral–algal phase shift was lowered by acidification and warming. These analyses support two important conclusions: Firstly, reefs already subjected to herbivore overfishing and nutrification are likely to be more vulnerable to increasing CO2. Secondly, under CO2 regimes above 450–500 ppm, management of local-scale disturbances will become critical to keeping reefs within an Acropora-rich domain.
TL;DR: In this paper, a Cd1−xZnxS solid solution with nano-twin structures is synthesized and exhibits superior photocatalytic activities for H2 evolution from water under visible light irradiation (λ ≥ 430 nm) without noble metal co-catalysts.
Abstract: Cd1−xZnxS solid solution with nano-twin structures are synthesized and exhibit superior photocatalytic activities for H2 evolution from water under visible light irradiation (λ ≥ 430 nm) without noble metal co-catalysts. Such Cd0.5Zn0.5S nanocrystals show the highest activity for hydrogen evolution with an extremely high apparent quantum yield (AQY = 43%) at 425 nm, achieving a hydrogen evolution rate of 1.79 mmol h−1 without noble metals. The hydrogen evolution rate of 1.70 mmol h−1 was achieved under simulated sunlight conditions (without infrared light). The “back to back” potential formed by parallel nano-twins in the Cd1−xZnxS crystals can significantly improve the separation of the photo-generated electrons/holes (preventing their recombination) thus enhancing the photocatalytic activity. Photodeposition experiments of noble metals strongly support such a mechanism. It is found that noble metals were selectively photo-deposited at central regions between the twin boundaries. The concentration of free electrons at the central region of twins was markedly higher and the twins can effectively separate the H2 evolution sites (electrons) from oxidation reaction sites (holes).
TL;DR: Online delivery of CBT, with minimal therapist support, is equally efficacious as clinic-based, face-to-face therapy in the treatment of anxiety disorders among adolescents, with benefits of reduced therapist time and greater accessibility for families who have difficulty accessing clinic- based CBT.
Abstract: The study examined the relative efficacy of online (NET) versus clinic (CLIN) delivery of cognitive behavior therapy (CBT) in the treatment of anxiety disorders in adolescents. Participants included 115 clinically anxious adolescents aged 12 to 18 years and their parent(s). Adolescents were randomly assigned to NET, CLIN, or wait list control (WLC) conditions. The treatment groups received equivalent CBT content. Clinical diagnostic interviews and questionnaire assessments were completed 12 weeks after baseline and at 6- and 12-month follow-ups. Assessment at 12 weeks post-baseline showed significantly greater reductions in anxiety diagnoses and anxiety symptoms for both NET and CLIN conditions compared with the WLC. These improvements were maintained or further enhanced for both conditions, with minimal differences between them, at 6- and 12-month follow-ups. Seventy-eight percent of adolescents in the NET group (completer sample) no longer met criteria for the principal anxiety diagnosis at 12-month follow-up compared with 80.6 in the CLIN group. Ratings of treatment credibility from both parents and adolescents were high for NET and equivalent to CLIN. Satisfaction ratings by adolescents were equivalent for NET and CLIN conditions, whereas parents indicated slightly higher satisfaction ratings for the CLIN format. Online delivery of CBT, with minimal therapist support, is equally efficacious as clinic-based, face-to-face therapy in the treatment of anxiety disorders among adolescents. This approach offers a credible alternative to clinic-based therapy, with benefits of reduced therapist time and greater accessibility for families who have difficulty accessing clinic-based CBT.
TL;DR: An overview of various modeling approaches of skin permeability with respect to their advantages, limitations and future prospects is provided.
TL;DR: In this paper, a case study approach is employed as a research method to improve the understanding of carbon footprint within the context of automobile supply chain management, and a map of product carbon footprint facilitates identification and measurement of carbon emissions across the supply chain.
TL;DR: In this article, a study of 367 SME Australian firms reveals that two key marketing capabilities, namely branding and innovation, have major performance outcomes in the SME B2B context, with innovation capability the strongest determinant of SME performance.
TL;DR: The problem of byproduct precipitation and catalyst blockage at high NaBH4 concentrations must be addressed in order to produce a hydrogen storage system capable of meeting the DOE target of 5.5% H2 (2015).
TL;DR: The work of the ISO/TC 43/SC 1 Working Group 54 as mentioned in this paper has been formed with a remit of standardization for perceptual assessment of human sound preference (in outdoor space) using questionnaires.
TL;DR: In this paper, the authors report on the first phase of a longitudinal study that investigates beginning pre-service teachers' views of what it is to be a teacher, highlighting the similarities and more notable contrasts in individual perceived ratings of teacher self-efficacy.
Abstract: Pre-service teacher education programs play an important role in the development of beginning teacher' self-efficacy and identity. Research suggests that this development is influenced by the 'apprenticeship of learning'. However, there remains limited research about the self-efficacy beliefs and identity construction of beginning pre-service teachers entering teacher training, and the impact of the education programs on the development of these attributes. This paper reports on the first phase of a longitudinal study that investigates beginning pre-service teachers' views of what it is to be a teacher. In 2010, the Teacher Sense of Efficacy Scale (Tschannen- Moran & Woolfolk Hoy, 2001) was administered twice (start and end of the year) to beginning pre-service teachers enrolled in three programs: the Graduate Diploma of Early Childhood Education; the Graduate Diploma of Education - Primary; and the Graduate Diploma of Education - Secondary. Identity data in the form of text and visual representations of the teachers were also collected. This paper focuses on the results from the self-efficacy scale, highlighting the similarities and more notable contrasts in individual perceived ratings of teacher self-efficacy. Implications for further research are shared.