Pierre-and-Marie-Curie University

About: Pierre-and-Marie-Curie University is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Raman spectroscopy. The organization has 34448 authors who have published 56139 publications receiving 2392398 citations.

Avoiding traceroute anomalies with Paris traceroute

Abstract: Traceroute is widely used, from the diagnosis of network problems to the assemblage of internet maps. However, there are a few serious problems with this tool, in particular due to the presence of load balancing routers in the network. This paper describes a number of anomalies that arise in nearly all traceroute-based measurements. We categorize them as "loops", "cycles", and "diamonds". We provide a new publicly-available traceroute, called Paris traceroute, which controls packet header contents to obtain a more precise picture of the actual routes that packets follow. This new tool allows us to find conclusive explanations for some of the anomalies, and to suggest possible causes for others.

The Aegean Sea

Abstract: We summarize briefly the main features of a kinematic model of evolution of the Aegean area since 13 Ma. The formation of the Aegean Sea by extensional tectonics is related to the subduction of the Mediterranean floor below the Hellenic arc. We then make a quantitative estimate of vertical movements in the Aegean area, on the basis of geological data, and demonstrate that the outer arc was built since the beginning of this episode of subduction by vertical uplift. The easiest way to explain the uplift is by underplating. Finally, we discuss briefly the dynamics of the subduction - marginal sea formation processes in this continental collision framework.

The upgraded DØ detector

Abstract: The D0 experiment enjoyed a very successful data-collection run at the Fermilab Tevatron collider between 1992 and 1996. Since then, the detector has been upgraded to take advantage of improvements to the Tevatron and to enhance its physics capabilities. We describe the new elements of the detector, including the silicon microstrip tracker, central fiber tracker, solenoidal magnet, preshower detectors, forward muon detector, and forward proton detector. The uranium/liquid-argon calorimeters and central muon detector, remaining from Run I, are discussed briefly. We also present the associated electronics, triggering, and data acquisition systems, along with the design and implementation of software specific to D0.

Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission

Abstract: In sexual reproduction of most animals, the spermatozoon provides DNA and centrioles, together with some cytoplasm and organelles, to the oocyte that is being fertilized. Paternal mitochondria and their genomes are generally eliminated in the embryo by an unknown degradation mechanism. We show that, upon fertilization, a Caenorhabditis elegans spermatozoon triggers the recruitment of autophagosomes within minutes and subsequent paternal mitochondria degradation. Whereas the nematode-specific sperm membranous organelles are ubiquitinated before autophagosome formation, the mitochondria are not. The degradation of both paternal structures and mitochondrial DNA requires an LC3-dependent autophagy. Analysis of fertilized mouse embryos shows the localization of autophagy markers, which suggests that this autophagy event is evolutionarily conserved to prevent both the transmission of paternal mitochondrial DNA to the offspring and the establishment of heteroplasmy.