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Institution

Technion – Israel Institute of Technology

EducationHaifa, Israel
About: Technion – Israel Institute of Technology is a education organization based out in Haifa, Israel. It is known for research contribution in the topics: Population & Nonlinear system. The organization has 31714 authors who have published 79377 publications receiving 2603976 citations. The organization is also known as: Technion Israel Institute of Technology & Ṭekhniyon, Makhon ṭekhnologi le-Yiśraʼel.


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Journal ArticleDOI
TL;DR: It is shown that different management decisions may result when uncertainty in utilities and probabilities are considered in decision-making problems and the importance of a full assessment of uncertainty in conservation management decisions is highlighted.
Abstract: In conservation biology it is necessary to make management decisions for endangered and threatened species under severe uncertainty. Failure to acknowledge and treat uncertainty can lead to poor decisions. To illustrate the importance of considering uncertainty, we reanalyze a decision problem for the Sumatran rhino, Dicerorhinus sumatrensis, using information-gap theory to propagate uncertainties and to rank management options. Rather than requiring information about the extent of parameter uncertainty at the outset, information-gap theory addresses the question of how much uncertainty can be tolerated before our decision would change. It assesses the robustness of decisions in the face of severe uncertainty. We show that different management decisions may result when uncertainty in utilities and probabilities are considered in decision-making problems. We highlight the importance of a full assessment of uncertainty in conservation management decisions to avoid, as much as possible, undesirable outcomes.

399 citations

Journal ArticleDOI
TL;DR: In this article, a review of solid-catalyzed oxidation and reduction processes for the treatment of wastewater that contains small concentrations of toxic compounds and for which separation is not economical while biological treatment is not feasible.
Abstract: The paper reviews solid-catalyzed oxidation and reduction processes for the treatment of wastewater that contains small concentrations of toxic compounds and for which separation is not economical while biological treatment is not feasible. Specifically, the objectives are (1) to understand the interactions between catalytic materials and various pollutants, (2) to provide a database for catalyst selection, and (3) to assess the potential of these processes for commercialization. The review suggests the following well-investigated solutions: (1) Supported metal (Ru/CeO2, Pt/CeO2, and Ru/C) and metal oxides (CuO−ZnO−CoO, MnO2/CeO2, CoO/Bi2O3, and V2O5/Al2O3) are the most promising catalysts for the destruction of refractory organic compounds with nearly 100% selectivity to CO2; (2) CoO/CeO2 and MnO2/CeO2 are the most active catalysts for ammonia oxidation at temperatures of 263−400 °C; (3) activated carbon, preferably in the presence of copper ions, is an active catalyst for the oxidation of cyanides and ...

399 citations

Journal ArticleDOI
TL;DR: Several potentially significant differences exist between porcine and human hearts, and it is important that these differences are considered as the arguments continue concerning the use of transgenic pig hearts for xenotransplantation.
Abstract: Transgenic technology has potentially solved many of the immunological difficulties of using pig organs to support life in the human recipient. Nevertheless, other problems still remain. Knowledge of cardiac anatomy of the pig (Sus scrofa) is limited despite the general acceptance in the literature that it is similar to that of man. A qualitative analysis of porcine and human cardiac anatomy was achieved by gross examination and dissection of hearts with macrophotography. The porcine organ had a classic ‘Valentine heart’ shape, reflecting its location within the thorax and to the orientation of the pig's body (unguligrade stance). The human heart, in contrast, was trapezoidal in silhouette, reflecting man's orthograde posture. The morphologically right atrium of the pig was characterised by the tubular shape of its appendage (a feature observed on the left in the human heart). The porcine superior and inferior caval veins opened into the atrium at right angles to one another, whereas in man the orifices were directly in line. A prominent left azygous vein (comparable to the much reduced left superior caval or oblique vein in man) entered on the left side of the pig heart and drained via the coronary sinus. The porcine left atrium received only 2 pulmonary veins, whereas 4 orifices were generally observed in man. The sweep between the inlet and outlet components of the porcine right ventricle was less marked than in man, and a prominent muscular moderator band was situated in a much higher position within the porcine right ventricle compared with that of man. The apical components of both porcine ventricles possessed very coarse trabeculations, much broader than those observed in the human ventricles. In general, aortic-mitral fibrous continuity was reduced in the outlet component of the porcine left ventricle, with approximately two-thirds of the aortic valve being supported by left ventricular musculature. Several potentially significant differences exist between porcine and human hearts. It is important that these differences are considered as the arguments continue concerning the use of transgenic pig hearts for xenotransplantation.

399 citations

Journal ArticleDOI
TL;DR: In this article, the authors characterized the cardiomyocyte differentiation potential of human induced pluripotent stem (hiPS) cells and studied the molecular, structural, and functional properties of the generated hiPS-derived Cardiomyocytes.
Abstract: Background— The ability to derive human induced pluripotent stem (hiPS) cell lines by reprogramming of adult fibroblasts with a set of transcription factors offers unique opportunities for basic and translational cardiovascular research. In the present study, we aimed to characterize the cardiomyocyte differentiation potential of hiPS cells and to study the molecular, structural, and functional properties of the generated hiPS-derived cardiomyocytes. Methods and Results— Cardiomyocyte differentiation of the hiPS cells was induced with the embryoid body differentiation system. Gene expression studies demonstrated that the cardiomyocyte differentiation process of the hiPS cells was characterized by an initial increase in mesoderm and cardiomesoderm markers, followed by expression of cardiac-specific transcription factors and finally by cardiac-specific structural genes. Cells in the contracting embryoid bodies were stained positively for cardiac troponin-I, sarcomeric α-actinin, and connexin-43. Reverse-tra...

399 citations

Journal ArticleDOI
TL;DR: A characterization of learnability in the probabilistic concept model, solving an open problem posed by Kearns and Schapire, and shows that the accuracy parameter plays a crucial role in determining the effective complexity of the learner's hypothesis class.
Abstract: Learnability in Valiant's PAC learning model has been shown to be strongly related to the existence of uniform laws of large numbers These laws define a distribution-free convergence property of means to expectations uniformly over classes of random variables Classes of real-valued functions enjoying such a property are also known as uniform Glivenko-Cantelli classes In this paper, we prove, through a generalization of Sauer's lemma that may be interesting in its own right, a new characterization of uniform Glivenko-Cantelli classes Our characterization yields Dudley, Gine´, and Zinn's previous characterization as a corollary Furthermore, it is the first based on a Gine´, and Zinn's previous characterization as a corollary Furthermore, it is the first based on a simple combinatorial quantity generalizing the Vapnik-Chervonenkis dimension We apply this result to obtain the weakest combinatorial condition known to imply PAC learnability in the statistical regression (or “agnostic”) framework Furthermore, we find a characterization of learnability in the probabilistic concept model, solving an open problem posed by Kearns and Schapire These results show that the accuracy parameter plays a crucial role in determining the effective complexity of the learner's hypothesis class

398 citations


Authors

Showing all 31937 results

NameH-indexPapersCitations
Robert Langer2812324326306
Nicholas G. Martin1921770161952
Tobin J. Marks1591621111604
Grant W. Montgomery157926108118
David Eisenberg156697112460
David J. Mooney15669594172
Dirk Inzé14964774468
Jerrold M. Olefsky14359577356
Joseph J.Y. Sung142124092035
Deborah Estrin135562106177
Bruce Yabsley133119184889
Jerry W. Shay13363974774
Richard N. Bergman13047791718
Shlomit Tarem129130686919
Allen Mincer129104080059
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023147
2022390
20213,397
20203,526
20193,273
20183,131