University of Seville

About: University of Seville is a education organization based out in Seville, Andalucía, Spain. It is known for research contribution in the topics: Population & Context (language use). The organization has 20098 authors who have published 47317 publications receiving 947007 citations. The organization is also known as: Universidad de Sevilla.

Electric Energy Systems : Analysis and Operation

Abstract: Electric Energy Systems-An Overview I.J. Perez Arriaga, H. Rudnick, and M. Rivier Steady-State Single-Phase Models of Power System Components E. Handschin, A. F. Otero, and J. Cidras Load Flow A. Gomez-Exposito and F. L. Alvarado State Estimation A. Gomez-Exposito and A. Abur Economics of Electricity Generation F. D. Galiana and A. J. Conejo Optimal and Secure Operation of Transmission Systems J. L. Martinez Ramos and V. H. Quintana Three-Phase Linear and Nonlinear Models of Power System Components E. Acha and J. Usaola Fault Analysis and Protection Systems J. Cidras, J. F. Minambres, and F. L. Alvarado Frequency and Voltage Control G. Andersson, C. Alvarez Bel, and C. Canizares Angle, Voltage, and Frequency Stability C. Canizares, L. Rouco, and G. Andersson Three-Phase Power Flow and Harmonic Analysis W. Xu and J. G. Mayordomo Electromagnetic Transients Analysis J. A. Martinez-Velasco and J. Marti Appendix A: Solution of Linear Equation Systems F. L. Alvarado and Antonio Gomez-Exposito Appendix B:Mathematical Programming A. J. Conejo Appendix C:Dynamic Models of Electric Machines L. Rouco Index

Frequency Regulation Contribution Through Variable-Speed Wind Energy Conversion Systems

Abstract: This paper presents a new method to enhance the participation of variable-speed wind energy conversion systems (WECS) in existing frequency regulation mechanisms. The proposed approach, based on a modified inertial control scheme, takes advantage of the fast response capability associated with electronically-controlled WECS, allowing the kinetic energy stored by rotational masses to be partly and transiently released in order to provide earlier frequency support. An additional improvement is achieved by communicating the WECS response to conventional generators so that these can eventually take care of the full load imbalance. Several simulations using a two-area test system are performed to demonstrate the benefits of the proposed scheme.

Treatment of experimental arthritis by inducing immune tolerance with human adipose‐derived mesenchymal stem cells

Abstract: Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease caused by loss of immunologic self tolerance and characterized by chronic joint inflammation. Adult mesenchymal stem cells (MSCs) were recently found to suppress effector T cell responses and to have beneficial effects in various immune disorders. The purpose of this study was to examine a new therapeutic strategy for RA based on the administration of human adipose-derived MSCs (AD-MSCs). Methods DBA/1 mice with collagen-induced arthritis were treated with human AD-MSCs after disease onset, and clinical scores were determined. Inflammatory response was determined by measuring the levels of different mediators of inflammation in the joints and serum. The Th1-mediated autoreactive response was evaluated by determining the proliferative response and cytokine profile of draining lymph node cells stimulated with the autoantigen. The number of Treg cells and the suppressive capacity on self-reactive Th1 cells were also determined. Results Systemic infusion of human AD-MSCs significantly reduced the incidence and severity of experimental arthritis. This therapeutic effect was mediated by down-regulating the 2 deleterious disease components: the Th1-driven autoimmune and inflammatory responses. Human AD-MSCs decreased the production of various inflammatory cytokines and chemokines, decreased antigen-specific Th1/Th17 cell expansion, and induced the production of antiinflammatory interleukin-10 in lymph nodes and joints. Human AD-MSCs also induced de novo generation of antigen-specific CD4+CD25+FoxP3+ Treg cells with the capacity to suppress self-reactive T effector responses. Conclusion Human AD-MSCs emerge as key regulators of immune tolerance by inducing the generation/activation of Treg cells and are thus attractive candidates for a cell-based therapy for RA.

Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008.

Abstract: Olive oil (OO) is the most representative food of the traditional Mediterranean Diet (MedDiet). Increasing evidence suggests that monounsaturated fatty acids (MUFA) as a nutrient, OO as a food, and the MedDiet as a food pattern are associated with a decreased risk of cardiovascular disease, obesity, metabolic syndrome, type 2 diabetes and hypertension. A MedDiet rich in OO and OO per se has been shown to improve cardiovascular risk factors, such as lipid profiles, blood pressure, postprandial hyperlipidemia, endothelial dysfunction, oxidative stress, and antithrombotic profiles. Some of these beneficial effects can be attributed to the OO minor components. Therefore, the definition of the MedDiet should include OO. Phenolic compounds in OO have shown antioxidant and anti-inflammatory properties, prevent lipoperoxidation, induce favorable changes of lipid profile, improve endothelial function, and disclose antithrombotic properties. Observational studies from Mediterranean cohorts have suggested that dietary MUFA may be protective against age-related cognitive decline and Alzheimer's disease. Recent studies consistently support the concept that the OO-rich MedDiet is compatible with healthier aging and increased longevity. In countries where the population adheres to the MedDiet, such as Spain, Greece and Italy, and OO is the principal source of fat, rates of cancer incidence are lower than in northern European countries. Experimental and human cellular studies have provided new evidence on the potential protective effect of OO on cancer. Furthermore, results of case-control and cohort studies suggest that MUFA intake including OO is associated with a reduction in cancer risk (mainly breast, colorectal and prostate cancers).