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Institution

University of Würzburg

EducationWurzburg, Bayern, Germany
About: University of Würzburg is a education organization based out in Wurzburg, Bayern, Germany. It is known for research contribution in the topics: Population & Gene. The organization has 31437 authors who have published 62203 publications receiving 2337033 citations. The organization is also known as: Julius-Maximilians-Universität Würzburg & Würzburg University.


Papers
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Journal ArticleDOI
TL;DR: The data indicate that PAMPs significantly contribute to SAR initiation in Arabidopsis and that tissue necroses at inoculation sites are dispensable for SAR activation, and that the magnitude of defence reactions such as SA accumulation, PR gene expression or camalexin accumulation induced at sites of virulent or avirulent P. syringae inoculation determines the extent of SAR in distant leaves.
Abstract: Systemic acquired resistance (SAR) is usually described as a phenomenon whereby localized inoculation with a necrotizing pathogen renders a plant more resistant to subsequent pathogen infection Here we show that Pseudomonas syringae strains for which Arabidopsis thaliana represents a non-host plant systemically elevate resistance although the underlying interactions neither trigger a hypersensitive response nor cause necrotic disease symptoms A similar enhancement of systemic resistance was observed when elicitor-active preparations of two typical bacterial pathogen-associated molecular patterns (PAMPs), flagellin and lipopolysaccharides (LPS), were applied in a localized manner Several lines of evidence indicate that the observed systemic resistance responses are identical to SAR Localized applications of non-adapted bacteria, flagellin or LPS elevate levels of the SAR regulatory metabolite salicylic acid (SA) and pathogenesis-related (PR) gene expression not only in treated but also in distant leaves All treatments also systemically increase expression of the SAR marker gene FLAVIN-DEPENDENT MONOOXYGENASE 1 Further, a whole set of SAR-deficient Arabidopsis lines, including mutants in SA biosynthesis and signalling, are impaired in establishing the systemic resistance response triggered by non-host bacteria or PAMPs We also show that the magnitude of defence reactions such as SA accumulation, PR gene expression or camalexin accumulation induced at sites of virulent or avirulent P syringae inoculation but not the extent of tissue necrosis during these interactions determines the extent of SAR in distant leaves Our data indicate that PAMPs significantly contribute to SAR initiation in Arabidopsis and that tissue necroses at inoculation sites are dispensable for SAR activation

417 citations

Journal ArticleDOI
TL;DR: The goal of the present document is to review the most recent achievements in the field and to analyze future directions in research and development.

416 citations

Journal ArticleDOI
TL;DR: Vav is a crucial regulator of TCR-mediated Ca2+ flux, cytoskeletal reorganization and TCR clustering, and these are required for T-cell maturation, interleukin-2 production and cell cycle progression.

415 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek4  +2815 moreInstitutions (169)
TL;DR: In this article, a search for new phenomena in final states with an energetic jet and large missing transverse momentum was performed using 20.3 fb(-1) of root s = 8 TeV data collected in 2012.
Abstract: Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb(-1) of root s = 8 TeV data collected in 2012 ...

414 citations


Authors

Showing all 31653 results

NameH-indexPapersCitations
Peer Bork206697245427
Cyrus Cooper2041869206782
D. M. Strom1763167194314
George P. Chrousos1691612120752
David A. Bennett1671142109844
Marc W. Kirschner162457102145
Josef M. Penninger154700107295
William A. Catterall15453683561
Rui Zhang1512625107917
Niels Birbaumer14283577853
Kim Nasmyth14229459231
James J. Gross139529100206
Michael Schmitt1342007114667
Jean-Luc Brédas134102685803
Alexander Schmidt134118583879
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023111
2022398
20212,960
20202,899
20192,714
20182,447